1

RESUME

NAME:Sun-Woong KANG

TITLE:Ph.D. candidate/Stem cells and Tissue Engineering Lab.Dept of Chemical Engineering

BIRTH DATE:May9, 1975

MARITAL STATUS:non-married

TELEPHONE:+82-2-2297-0838 (Lab)

FAX:+82-2-2291-0838 (Lab)

ADDRESS:Stem Cells/Tissue Eng. Lab. Department of Chemical Engineering, HanyangUniversity 17 Haengdang-dong, Seongdong-ku, Seoul 133-791, Korea

E-mail:

RESEARCH:Development of tissue engineered organ

(Cartilage and Bone)

SUPERVISOR:Prof. Byung-Soo Kim ()

EDUCATION:1995. 3 - 2002. 2, BS

Dept of Chemical Engineering, Hanyang Univ.KOREA

2002. 3 - 2004. 2, MS

Dept of Chemical Engineering, Hanyang Univ.KOREA

2004.3 - present, Ph.D. candidate

Dept of Chemical Engineering, Hanyang Univ.KOREA

RESEARCH INTERESTS:Tissue engineered Bone and Cartilage, Controlled Drug Delivery using Degradable Polymers, Surface Modification for Biocompatibility, Medical Devices, Cell/Polymer Interactions.

PROFESSIONAL

ACTIVITIES:Member of Tissue Engineering & Regenerative Medicine International Society (TERMIS)

Member of the Society for Biomaterials (SFB)

Member of the Polymer Society of Korea

Member of the Korean Society for Biotechnology and Bioengineering

Member of the Korean Society for Biomaterials

Member of the Korean Tissue Engineering and Regenerative Medicine Society

RESEARCH EXPERIENCE:

Ph.D Student in Stem Cell/Tissue Engineering (from March2004to present)

Affiliation: Department of Chemical Engineering, HanyangUniversity

Thesis: Tissue engineering of bone and cartilage using stem cells

Research focus:

  • Tissue engineering of cartilage and bone using bone marrow-derived cells
  • Angiogenic therapy for treatment of ischemia
  • Regeneration of adipose tissue using adipose-derived stem cells, biodegradable polymer, and drug delivery

M.S. in Tissue Engineering (from March2002 to February 2004)

Affiliation: Department of Chemical Engineering, HanyangUniversity

Thesis: The study on biodegradable and injectable scaffolds for cartilage regeneration and bulking effect

Research focus:

  • In vivo regeneration of cartilage using injectable scaffolds and chondrocytes

PUBLICATION:17 Publications, 7 Presentations

  1. Lee SH, Kim BS, Kim SH, Choi SW, Jeong SI, Kwon IK, Kang SW, Nikolovski J, Mooney DJ, Han YK, Kim YH. Elastic Poly(glycolide-co-caprolactone) Scaffold for Tissue Engineering. Journal of Biomedical Materials Research2003;66A:29-37.
  2. Han SI, Kim BS, Kang SW, Hirofusa S, Im SS. Cellular interactions and Degradation of Aliphatic Poly(ester amide)s Derived from Glycine and/or 4-Amino butyric acid. Biomaterials2003;24:3453-3462.
  3. Cho SW, Kim IK, Lim SH, Kim DI, Kang SW, Kim SH, Kim YH, EY Lee, CY Choi, Kim BS. Smooth muscle-like tissues engineered with bone marrow stromal cells. Biomaterials2004;25:2979-2986.
  4. Jeong SI, Kim BS, Kang SW, Kwon JH, Lee YM, Kim SH, Kim YH. In vivo biocompatibility and degradation behavior of elastic poly(L-lactide-co-caprolactone) scaffolds. Biomaterials2004;25:5939-5946.
  5. Lee SH, Kim BS, Kim SH, Jeong SI, Kang SW, Kim YH. Thermally Produced Biodegradable Polymer Scaffolds for Cartilage Tissue Engineering. Macromolecular Bioscience2004;4:802-810.
  6. Cho ER, Kang SW, Kim BS. Poly(lactic-co-glycolic acid) microspheres as a potential bulking agent for urological injection therapy: preliminary results. Journal of Biomedical Materials Research: Part B-Applied Biomaterials 2005;72B:166-172.
  7. Kang SW, Park JH, Kim BS. Use of neonatal chondrocytes for cartilage tissue engineering. Journal of Microbiology and Biotechnology2005;15:259-264.
  8. Kang SW, Jeon O, Kim BS. Poly(lactic-co-glycolic acid) microspheres as an injectable scaffold for cartilage tissue engineering. Tissue Engineering2005;11:438-447.
  9. Kang SW, Cho ER, Kim BS. PLGA Microspheres in Hyaluronic Acid Gel as a Potential Bulking Agent for Urologic and Dermatologic Injection Therapies. Journal of Microbiology and Biotechnology2005;15:510-518.
  10. Han SI, Kang SW, Kim BS, Im SS. A novel polymeric ionomer as a potential biomaterial : crystalliztion behavior, degradation, and in vitro cellular interactions. Advanced Funtional Materials 2005;15:367-374.
  11. Cho ER, Kang SW, Park HJ, Cho YS, Lee YS, Kim JC, Kim BS. Submucosal Injection of Poly(lactic-co-glycolic acid) Microspheres in Rabbit Bladder as a Potential Treatment for Urinary Incontinence and Vesicoureteral Reflux; Preliminary Results. Journal of Biomaterials Science Polymer Edition2005;16: 1109-1120.
  12. Jeon Oju, Kang SW, Lim HW, Chung JH, Kim BS. Long-term and zero-order release of basic fibroblast growth factor from heparin-conjugated poly(L-lactide-co-glycolide) nanospheres and fibrin gel. Biomaterials2006;27(8):1598-607.
  13. Jeon O, Kang SW, Lim HW, Choi DH, Kim DI, Lee SH, Chung JH, Kim BS. Synergistic effect of sustained delivery of basic fibroblast growth factor and bone marrow mononuclear cell transplantation on angiogenesis in mouse ischemic limbs. Biomaterials2006;27:1617-25.
  14. Kang SW, Son SM, Lee JS, Lee ES, Lee KY, Park SG, Park JH, Kim BS. Regeneration of Whole Meniscus Using Meniscal Cells and Polymer Scaffolds in a Rabbit Total Meniscectomy Model. Journal of Biomedical Materials Research: Part A2006;77(4);659-71.
  15. Cho SW, Gwak SJ, Kang SW, Bhang SH, Song KW, Yang YS, Choi CY, Kim BS. Enhancement of angiogenic efficacy of human cord blood cell transplantation by cell transplantation using matrix and combined therapy with sustained delivery of basic fibroblast growth fact. Tissue Engineering2006;12(6):1651-1661.
  16. Kang SW, Yoon JR, Lee JS, Kim HJ, Lim HC, Lim HW, Park JH, Kim BS. (2006). Poly(lactic-co-glycolic acid) Microsphere as an Injectable Cell Carrier for Cartilage Regeneration in Rabbit Knee. Journal of Biomaterials Science Polymer Edition2006;17(8):925-939.
  17. Kang SW, Cho ER, Jeon O, Kim BS. The effect of microsphere degradation rate on the efficacy of polymeric microspheres as bulking agents: an 18-month follow-up study. Journal of Biomedical Materials Research: Part B-Applied Biomaterials (in press).
  18. Kang SW, Yoo SP, Kim BS. Effect of chondrocyte passage number on histological aspects of tissue-engineered cartilage (Submitted to “Bio-medical mamterials and engineering”).
  19. Kang SW, Yang HS, Han DK, Kim BS. Apatite-coated poly(lactic-co-glycolic acid) microspheres as an injectable scaffold for bone tissue engineering. (Submitted to “Journal of Biomedical Materials Research-part A”).

PRESENTATIONS AT INTERNATIONAL CONFERENCES:

  1. The 5th Annual Meeting of the Tissue Engineering Society International (TESI), Kobe, Japan, December 2002. Poster Presentation: “Biodegradable microspheres as cell culture substrates and cell transplantation matrices”
  2. The 5th World Biomaterials Congress, Sydney, Australia, May, 2004. Oral Presentation: “Tissue-Engineered meniscal cartilage : histological and biomechanical results in a rabbit model”
  3. The 7th Annual Meeting of the Tissue Engineering Society International (TESI), Orlando, December 2003. Poster Presentation: “Synergistic effect of basic fibroblast growth factor, granulocyte-colony stimulating factor, and bone marrow mononuclear cell transplantation on angiogenesis in mouse ischemic limbs”
  4. The 30th Annual Meeting and Exposition New Applications and Technologies of the Society for Biomaterials, Memphis, USA, April 2005. Poster Presentation: “Biodegradable polymer microspheres as a potentioal bulking agent for urologic and dermatologic injection therapies”
  5. The 30th Annual Meeting and Exposition New Applications and Technologies of the Society for Biomaterials, Memphis, USA, April 2005. Poster Presentation: “Enhancement of angiogenic efficacy of cord blood cell transplantation by cell transplantation using matrix and combination with bFGF sustained delivery”
  6. The 8th Annual Meeting of the Tissue Engineering Society International (TESI), Shanghai, China, October 2005. Poster Presentation: “Poly(lactic-co-glycolic acid) microspheres as an injectable scaffold for cartilage tissue engineering”
  7. The 8th Annual Meeting of the Tissue Engineering Society International (TESI), Shanghai, China, October 2005. Poster Presentation: “Enhancement of angiogenic efficacy of human cord blood cell transplantation by cell transplantation using matrix and combined therapy with sustained delivery of basic fibroblast growth factor”

EXPERIMENTAL SKILLS:

  • Animal cell culture: primary culture of various types of cells (e.g., endothelial cells, smooth muscle cells, fibroblasts, chondrocytes, and osteoblasts)
  • Stem cell culture and differentiation: mononuclear cell isolation (bone marrow), bone marrow stem cell culture and differentiation (chondrogenic and osteogenic differentiation), adipose-derived stem cell culture and differentiation (adipocyte differentiation)
  • Cell characterization: immunochemical cell staining, RT-PCR
  • Histology: staining related to vascular, muscular, cardiac and adipose tissue (H&E, collagen, elastin, and lipid staining)
  • Immunohistochemistry: enzyme-linked immunohistochemical staining, immunofluorescent staining, TUNEL (apoptosis) staining
  • Laboratory animal experiments:small animal (mouse, rat, and rabbit) handling, anesthesia, and surgery
  • Molecular biological techniques: RT-PCR, SDS-PAGE, western blot, ELISA, DNA, RNA, protein analysis
  • Scaffold fabrication: synthetic biodegradable polymer scaffold, microsphere, nanosphere
  • Microscopic analyses: confocal microscopy, fluorescent microscopy, SEM, TEM
  • Polymer synthesis and characterization