DRAFT DOCUMENT
UWA–HMGU-UCL Third Collaborative Research Meeting
Wednesday 25th November – Friday 27th November 2015
UHU Research Symposium
“Healing, Repair and Regeneration: development of novel therapeutic strategies"
Wednesday 25th November
8.30 – 9.00 Registration
Foyer, Harry Perkins Institute of Medical Research
9.00 – 9.15 Welcome
Chair: Professor Geoffrey Laurent
Professor Peter Klinken
Chief Scientist of Western Australia
Office of Science, Department of the Premier and Cabinet
Session 1: Stem cells and tissue regeneration
Chair: Dr Melanie Königshoff
Keynote Presentation
09.15 – 09.35 Associate Professor Julian Heng
Harry Perkins Institute of Medical Research, UWA
Title: Neural stem cells: from embryonic development to cell-based therapies for the treatment of neurological disorder
09.35 – 09.55 Dr Yuval Rinkevich
Comprehensive Pneumology Center (CPC), Helmholtz Zentrum München
Title: Cell lineage perspectives of fibrosis.
09.55 - 10.15 Dr Yuben Moodley
Institute for Respiratory Health and School of Medicine and Pharmacology, UWA
Title: The viability of testing stem cells in lung slices.
ASSCR Student and ECR Presentations – Part I
10.15 - 10.25 Abraham John
Harry Perkins Institute of Medical Research Centre for Medical Research, UWA
Title: A cellular model of dedifferentiation in high glucose environments
10.25– 10.35 Dr Luke Diepeveen
The Centre for Medical Research, Harry Perkins Institute of Medical Research, UWA
Title: Epigenetic modulators enhance constitutive and liver-specific reporter expression in murine liver progenitor cell lines
10.35-10.45 Alex Tang
Experimental and Regenerative Neurosciences, School of Animal Biology, UWA
Title: Repetitive transcranial magnetic stimulation induces collateral reinnervation in the adult mouse cerebellum
10.45 – 10.55 Group Photo
Foyer of Harry Perkins Institute of Medical Research
10.50 – 11.15 Tea and Coffee Break
Sponsored by Admedus
11.15 – 11.30 Professor Robyn Owens
Deputy Vice-Chancellor (Research), UWA.
Session 2: Bioengineering extracellular matrix and scaffolds to support tissue regeneration and repair
Chair: Professor Deirdre Coombe
11.30 – 11.50 Dr Yu Suk Choi
School of Anatomy, Physiology and Human Biology, UWA
Title: Tunable stiffness gradient hydrogels for stem cell mechanobiology
11.50 – 12.10 Associate Professor Rodney Dilley
Ear Science Institute Australia and School of Surgery, UWA
Title: Tissue engineering scaffolds for regenerative surgery in the ear
12.10 – 12.30 Associate Professor Tim Sercombe
School of Mechanical and Chemical Engineering, UWA
Title: 3D Printing and Tissues Engineering
ASSCR Student and ECR Presentations – Part II
12.30 – 12.40 Peijun Gong
Optical+Biomedical Engineering Laboratory, School of Electrical, Electronic & Computer Engineering, UWA
Title: Assessing burn scars treated with ablative laser fractionation using optical coherence tomography
12.40 – 12.50 Andrew Stevenson
Burn Injury Research Unit, School of Surgery, UWA
Title: Epigenetic changes after burn injury: a profile of human scar cells
12.50 – 13.00 Kalina Makowiecki
Experimental and Regenerative Neurosciences, School of Animal Biology, UWA
Title: Low-intensity repetitive transcranial magnetic stimulation modulates visual evoked responses depending on activity during stimulation
13.00 – 13.10 Mansour Alghamdi
Burn Injury Research Unit, School of Surgery, UWA
Title: Epigenetic modification in keloid scars
13.10 -14.10 Lunch
Foyer, Harry Perkins Institute of Medical Research
Sponsored by Orthocell
Session 3: Cellular and molecular mechanisms driving cancer and chronic diseases
Chair: Professor Oliver Eickelberg
14.10 – 14.30 Professor Steve Wilton
Centre for Comparative Genomics, Murdoch University and Western Australian Neuroscience Research Institute
Title: The application of therapeutic alternative splicing to Duchenne muscular dystrophy: a clinical trial update
14.30 – 14.50 Dr Melanie Königshoff,
Institute for Lung Biology and Disease (iLBD) and Comprehensive Pneumology Center (CPC), Helmholtz Zentrum München
Title: Lung epithelial Cell Plasticity: Similarities in lung cancer and fibrosis
14.50 – 15.10 Associate Professor Georgios Stathopoulus,
Institute for Lung Biology and Disease (iLBD) and Comprehensive Pneumology Center (CPC), Helmholtz Zentrum München
Title: Oncogene-driven chemokine signaling directs circulating tumor cells to the lungs
15.10 – 15.30 Professor Darryl Knight
School of Biomedical Sciences and Pharmacy, The University of Newcastle, NSW
and Centre for Cell Therapy and Regenerative Medicine, School of Medicine and Pharmacology, UWA
Title: Journey to the Centre of the lung in search of the origins of fibrosis
15.30 – 15.50 Dr Michael Edel,
University of Barcelona and Centre for Cell Therapy and Regenerative Medicine, School of Medicine and Pharmacology, UWA
Title: Direct cell reprogramming towards healing, repair and regeneration
15.50 – 16.20 Tea and Coffee
Foyer, Harry Perkins Institute of Medical Research
Session 4: Commercialisation of novel therapeutic technologies
Chairs: Associate Professor Rodney Dilley and Mrs Renate Schlusen
16.20 – 16.35 Simon Handford
Office of Research Enterprise, University of Western Australia
Title: Research commercialisation – preparing for success
16.35– 16.50 James Williams
Director, Dimerix Bioscience Pty Ltd
Title:
16.50- 17.05 Associate Professor Irmgard Irminger-Finger
Centre for Cell Therapy and Regenerative Medicine, School of Medicine and Pharmacology, UWA
Title: Setting up a biotech spin off company
17.05 – 17.25 Professor Minghao Zheng,
School of Surgery, UWA
Title: A commercial approach to cell therapies
17.25 – 17.35 Professor Geoff Laurent
Centre for Cell Therapy and Regenerative Medicine, School of Medicine and Pharmacology, UWA
ASSCR Awards and One Day Symposium close
17.35 – 18.55 Sundowner
Foyer of Harry Perkins Institute of Medical Research
All welcome
UHU Research Collaboration Workshops
Thursday 26th and Friday 27th November 2015
Thursday 26th November
Session 1: Translational research programmes
Chair: Dr Brendan McQuillan
09.00 - 09.20 Dr Marian Sturm
Cell and Tissue Therapies WA, Royal Perth Hospital and Centre for Cell Therapy and Regenerative Medicine, UWA
Title: Allogeneic mesenchymal stromal cells: proof of concept immune modulation studies
09.20 – 09.40 Professor Wendy Erber
Head of School, Pathology and Laboratory Medicine
Title: Applications of imaging flow cytometry for leukaemia
09.40-10.00 Dr Fred Chen
Lions Eye Institute, UWA Centre for Ophthalmology and Visual Science
Title: Challenges of cell therapy in treatment of retinal diseases
10.00 – 10.20 Associate Professor Lindy Fitzgerald
Experimental and Regenerative Neurosciences, School of Animal Biology, UWA
Title: Strategies to limit damage following injury to the central nervous system
10.30 – 11.00 Tea and Coffee Break
Foyer of the Harry Perkins Institute of Medical Research
11.00 – 11.45 Tour
Guided tour of the Harry Perkins Institute of Medical Research
Perkins Research Seminar
McCusker Auditorium, Harry Perkins Institute of Medical Research
12.00 – 13.00 Professor Oliver Eickelberg
Chairman, Comprehensive Pneumology Center (CPC),
Ludwig-Maximilians-University (LMU) and Helmholtz Zentrum München
Title: Novel biomarkers and therapeutic targets in lung fibrosis
Chair: Professor Geoffrey Laurent
13.00-13.50 Lunch
Foyer of Harry Perkins Institute of Medical Research
Session 2: Update on collaborative research projects
Chair: Dr Cecilia Prêle
13.50-14.10 Associate Professor Irmgard Irminger-Finger
Centre for Cell Therapy and Regenerative Medicine, School of Medicine and Pharmacology, UWA
Title: BARD1, an oncogene or tumour suppressor? Dissecting its roles in lung cancer and fibrosis
14.10-14:30 Dr Andrew Lucas
Institute of Respiratory Health and Centre for Cell Therapy and Regenerative Medicine, School of Medicine and Pharmacology, UWA
Title: Can IGF-1 trigger regenerative lung growth in adult lungs
14.30-14.50 Dr Sam McLenachan
Ocular Tissue Engineering Laboratory, Lions Eye Institute
Title: Development of Autologous Stem Cell Therapies for Retinal Disorders
14.50 – 15.10 Professor Gerard Hoyne
School of Health Sciences, The University of Notre Dame.
Centre for Cell Therapy and Regenerative Medicine, School of Medicine and Pharmacology, UWA
Title: The role of CDK4 in regulating beta cell viability and function.
15.10 – 15.45 Tea and Coffee Break
Foyer of the Harry Perkins Institute of Medical Research
Session 3: Cellular and molecular mechanisms in tissue repair and regeneration
Chair: Associate Professor Jennifer Rodger
15.45 – 16.05 Dr Isis Fernandez
Comprehensive Cardiopulmonary Center (CPC), Helmholtz Zentrum München
Title: Peripheral blood myeloid-derived suppressor cells reflect disease status in IPF
16.05 - 16.25 Dr Cecilia Prêle,
Centre for Cell Therapy and Regenerative Medicine, School of Medicine and Pharmacology, UWA and Institute of Respiratory Health
Title: STAT3-mediated cell regulation of lung fibrosis
16.25 - 16.45 Associate Professor Anthony Kicic
School of Paediatrics and Child Health, UWA and Telethon Kids Institute
Title: Airway epithelial repair in asthma: The long and short of it
Friday 27th November
Session 4: Tissue engineering and cellular reprogramming
Chair: Professor George Yeoh
09.00 – 09.20 Professor Stefan Liebau
Institute of Neuroanatomy, Eberhard Karls University, Tuebingen, Germany
Title: Returning a Look from the dish
09.20 – 9.40 Professor Deirdre Coombe
School of Biomedical Sciences, Curtin University
Title: A Xenogeneic-free, fibroblast-derived matrix maintains keratinocytes in a proliferative state.
9.40 – 10.00 Professor Katja Schenke-Layland
Dept. of Women’s Health, Research Institute for Women’s Health, Eberhard Karls University, Tuebingen, Germany
Title: Non-invasive optical tools for cell, tissue and organ monitoring
10.00 – 10.20 Associate Professor Stuart Hodgetts
School of Anatomy, Physiology and Human Biology, UWA
Title: Gene and Stem Cell Therapies for spinal cord Repair
10.20 – 10.40 Dr Fang-Xu Jiang
Harry Perkins Institute of Medical Research, Centre for Medical Research, UWA
Title: Transcriptomics analysis identifies pancreatic islet claudin 4 associated with glucose homeostatsis
10.40 – 11.10 Tea and Coffee Break
Foyer of Harry Perkins Institute of Medical Research
Session 5: Future directions for stem cells and regenerative medicine; key questions and cutting edge technologies
Chair : Dr Fred Chen
11.10 – 11.25 Dr Brendan Kennedy
School of Electrical, Electronic and Computer Engineering, UWA
Title: Optical elastography: imaging tissue stiffness on the micro-scale
11.25 - 11.40 Dr Michael Edel,
University of Barcelona and Centre for Cell Therapy and Regenerative Medicine, School of Medicine and Pharmacology, UWA
Title: A Summary of the Australian Academy of Science funded Think Tank on: The Future of Stem Cell Research in Australia. Sydney, July 2015.
11.40 – 11.55 Professor George Yeoh
Centre for Medical Research, UWA and Centre for Cell Therapy and Regenerative Medicine, School of Medicine and Pharmacology, UWA
Title: Can we make enough stem cells to treat everyone who needs them?
11.55 – 12.25 Open Floor Discussions
Lead by Professor Geoff Laurent and Dr Cecilia Prêle
Discussions on Future funding/directions for UHU Collaborative Research Network
12.25 Meeting close
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