CV: Rupesh Chikhale April, 2015
Mr. Rupesh V. Chikhale
Date of Birth: February 25, 1982 Nationality: Indian
Personal Details: Mobile: +91-8983387871
E-mail:
Address: Department of Pharmaceutical Sciences
Rashtrasant Tukadoji Maharaj Nagpur University
Mahatma Jyotiba Fuley Shaikshanik Parisar,
Amravati Road Campus, Nagpur – 440033
Maharashtra, India
Education
Jul, 2001- Apr, 2003 Diploma in Pharmacy
Marks Obtained: 75.90 % (Distinction)
Institute of Diploma in Pharmacy
Maharashtra State Board of Technical Education
Mumbai, Maharashtra, India
Aug, 2003- Apr, 2006 Bachelor of Pharmaceutical Sciences
Marks Obtained: 65 % (First Class)
Sharad Pawar College of Pharmacy
R. T. M. Nagpur University, Nagpur, Maharashtra, India
Jul, 2006 - Jun, 2008 Master of Pharmaceutical Sciences in
Pharmaceutical Chemistry
Marks Obtained: 65 % (First Class)
Sharad Pawar College of Pharmacy
R. T. M. Nagpur University, Nagpur, Maharashtra, India
Research Topic: ‘Synthesis and Pharmacological Evaluation of Some 3, 4 Disubstituted Pyrimidine-5-Carboxylate Derivatives’
Supervisor: Prof. V. V. Parashar and Prof. P. B. Khedekar
March, 2007 Graduate Aptitude Test in Engineering (GATE)-2007 in Pharmaceutical Sciences (PY); conducted by Indian Institute of Technology, Kanpur, India
Aug, 2012 – May, 2013 Post Graduate Diploma in Industrial and Intellectual property law
Marks Obtained: 67% (First Class, University First Merit)
Post Graduate Teaching Department of Law
R. T. M. Nagpur University, Nagpur, Maharashtra, India
Research topic: ‘A Study of Hatch-Waxman Act on Innovation in Drug Research and Its Indian Perspective’
Supervisor: Prof. S. M. Deshpande
Jul, 2009 – Aug, 2014 Ph. D. in Pharmaceutical Science (Faculty of Medicine)
(Thesis submitted) Department of Pharmaceutical Sciences
Rashtrasant Tukadoji Maharaj Nagpur University
Nagpur, Maharashtra, India
Topic: ‘Design, Synthesis and Pharmacological Evaluation of Some New Benzazole Derivatives’
Supervisor: Prof. P. B. Khedekar
Awards/ Grants/ Fellowships
1. Awarded first prize for Best Poster at National seminar on ‘Academia-Industry Collaboration: Hitherto and Challenges’ held on 21st September, 2007 at S. K. B. College of Pharmacy, Kamptee, Nagpur.
2. Junior Research Fellowship by All India Council for Technical Education, New Delhi India from 2006-2008 for pursuing M. Pharma.
3. Senior Research Fellowship by Council for Scientific and Industrial Research (CSIR), New Delhi, India for Ph.D. during 2011-2015.
4. International Travel Grant awarded by Department of Biotechnology to present an Oral Presentation at the 9th AIMEC2013 held at Taipei, Taiwan during 15th to 18th October, 2013.
5. The INSA-CSIR-DAE/BRNS-CICS Travel Fellowship awarded by Centre for International Co-operation in Science(CICS), Chennai to cover the travel related expenses for presentation at 9th Asian Federation for Medicinal Chemistry International symposium, 2013.
Publications
1. R. Chikhale*, A. Pant, S. Menghani, Design, synthesis and pharmacological evaluation of benzothiazolyl pyrimidine derivatives as selective voltage gated L-type calcium channel blockers. Communicated
2. R. Chikhale*, S. Menghani, R Babu, R Bansode, G. Bhargavi, N Karodia, M. V. Rajasekharan, A Paradkar, P Khedekar, Development of selective DprE1 inhibitors: Design, synthesis, crystal structure and antitubercular activity of benzothiazolylpyrimidine-5-carboxamides. European Journal of Medicinal Chemistry, 96 (2015) 30-46. Impact Factor: 3.432
3. R. V. Chikhale*, Amit M. Pant, Sunil S. Menghani, Pramod B. Khedekar, ‘Facile and efficient synthesis of benzoxazole derivatives using novel catalytic activity of PEG-SO3H’, Arabian Journal of Chemistry, Available online. Impact Factor: 2.266
4. R. V. Chikhale*, Amit M. Pant, Sunil S. Menghani, Pramod B. Khedekar, ‘Development of dual inhibitor targeting DprE1 and AHAS for treatment of M. tuberculosis infection’, BMC Infectious Diseases, 14, 2014,24. Impact Factor: 3.02
5. Amit M. Pant, R. V. Chikhale, Sunil S. Menghani, Pramod B. Khedekar, ‘LEDGF/p75 IN interaction inhibitors: in silico studies of an old target with novel appraoch’, BMC Infectious Diseases, 14, 2014,16. Impact Factor: 3.02
6. S. Menghani, R. Chikhale*, A. Raval, P. Wadibhasme, P. Khedekar, ‘Chandipura Virus: An emerging tropical pathogen’ Acta Tropica, 124, 1, October 2012, 1-14. Impact Factor: 2.722
7. R. V. Chikhale*, R. P. Bhole, P. B. Khedekar, K. P. Bhusari, ‘Synthesis and pharmacological investigation of some ethyl [6-methyl-2-methoxy-3-(substituted phenylethanone)-4-(substituted phenyl)]-1, 2, 3, 4-tetrahydropyrimidine-5-carboxylates’ European Journal of Medicinal Chemistry, 44 (2009) 3645–3653. IF=3.509
Books
Title: Alzheimer’s disease: Biomarkers and Drug Therapeutics,
Publisher: LAP Lambert Academic Publishing; ISBN: 978-3-659-21216-1
Authors: Pramod Khedekar, Pankaj Wadibhasme, Rupesh Chikhale.
Patents
1. ‘Novel benzazolyl quinazolinones for treatment of cardiovascular and neurological disorders’ Indian provisional patent application no. 502/mum/2013 (filed).
2. ‘Novel benzazolyl pyrimidines for treatment of neoplastic and cardiovascular disorders’ Indian provisional patent application no. 503/mum/2013 (filed).
Presentations (Selected and Oral Presentations)
International:
1. 2nd International Science Symposium on HIV and Infectious Diseases (HIV SCIENCE 2014), an Oral Presentation (Short e-poster) was delivered on ‘Development of dual inhibitors targeting DprE1 and AHAS for treatment of Mycobacterium tuberculosis infection’ organized by YRG Care at Chennai from 30th January – 1st February, 2014.
2. 27th International Carbohydrate Symposium (ICS27), an Oral Presentation was delivered on ‘Synthesis of novel benzazolyl furanose derivatives as potent anti-HIV agents’ held at Indian Institute of Science, Bangalore, India from 12th-17th January, 2014.
3. 9th AFMC International Medicinal Chemistry Symposium (AIMECS Taipei 2013), an Oral Presentation was delivered on ‘Development of pharmacophore and docking based 3D-QSAR models of benzoxazolthizolidinones as PPARγ agonist’ held at Taipei City, Taiwan from 15th – 18th October, 2013.
4. 16th International Symposium on Relations between Homogenous and Heterogeneous Catalysis, Japan (ISHHC-16), an Oral Presentation was delivered on ‘Understanding the distereoslectivity of bicyclic isoxazolidine obtained from DPTMS ether-catalysed reaction’ held at Hokkaido University, Sapporo, Japan from 4th – 9th August, 2013.
5. International symposium on clinical pharmacy education: Sharing the U. S. experiences, research poster on ‘Clinical spectrum of pediatric dermatology and use of topical corticosteroids’was presented Guru Nanak College of Pharmacy, Nagpur during 27th and 28th November, 2009.
6. IBRO sponsored First meeting of the Indian Subcontinent Branch of the International Neuropepetide Society (ISBINPS), presented research paper in poster session on ‘International Structural Neuroscience Conference on Peptides’ held at University Department of Pharmaceutical Sciences, Nagpur on 2nd - 3rd February, 2008.
National:
1. National Symposium on ‘Innovation in TB Diagnostics, Drug Targets and Biomarkers’ held at JB Tropical Disease Research Centre & Department of Biochemistry, Mahatma Gandhi Institute of Medical Sciences, Sevagram (Wardha), India a research paper in form of Poster was presented on ‘In silico studies, synthesis and evaluation of DprE1 and AHAS inhibitors for control of Mycobacterium tuberculosis’ during January 27-28, 2014.
Work Experience
Sep, 2010- Dec, 2013 Contributory Lecturer
Department of Pharmaceutical Sciences
Rashtrasant Tukadoji Maharaj Nagpur University
Nagpur, Maharashtra, India
Taught: Advanced Medicinal Chemistry, Organic Chemistry and Inorganic Chemistry
Aug, 2009- May, 10 Lecturer in Pharmacy
SPSS’s Institute of Pharmacy
Smt. Kishoritai Bhoyar College of Pharmacy
Kamptee, Nagpur, Maharashtra, India
Taught Pharmaceutical Chemistry, Human Anatomy and Physiology
May, 2008–Jul, 09 Lecturer in Pharmacy
BCYRC’s Institute of Pharmacy
KDK Engineering College Campus, Nagpur, Maharashtra, India
Taught Pharmaceutical Chemistry
Membership of Professional Bodies:
1. Young Member of the French Society for Medicinal Chemistry, membership no. 15006.
2. Life Membership as Registered Pharmacist with Maharashtra State Pharmacy Council, registration certificate no. 74866 dated 21st December, 2004.
Trainings:
1. Short term training at the National Institute of Malaria Research (NIMR), New Delhi during 1st – 15th December, 2012 under mentorship of Dr. Aparup Das, Scientist-F.
2. One month training at the University Institute of Pharmaceutical Sciences, Punjab University, Chandigarh under the Centre for Advanced studies during 1st -30th April, 2013 under mentorship of Prof. Ranju Bansal.
3. One month training under UGC-Networking Resource Centre, School of Chemistry, University of Hyderabad during 1st -30th October, 2014 for learning Single Crystal X-ray diffraction studies under Prof. M. V. Rajasekahran.
References:
1) Dr. Pramod B. Khedekar
Professor in Pharmaceutical Chemistry
Commonwealth Academic Fellow
Department of Pharmaceutical Sciences
Rashtrasant Tukadoji Maharaj Nagpur University
Nagpur - 440033, India
Email:
3) Dr. Madhukar R Tajne
Professor in Pharmaceutical Chemistry
Department of Pharmaceutical Sciences
Rashtrasant Tukadoji Maharaj Nagpur University
Nagpur - 440033, India
Email:
Residential Address
Rupesh V. Chikhale
C/o P. S. Dhote
Plot no. 1121 B, Ashirwad Nagar, Nagpur – 440024, India
Page 5 of 5