School of Applied Medical Sciences

Undergraduate Plan of Study for the Bachelor Degree in:

Pharmaceutical-Chemical Engineering

  1. General:

Classification /

Credit Hours

Compulsory /

Contact Hrs.

/

Total

University Requirements / 40 / 81
School Requirements / 28 / 36
Program Requirements / 87 / 109
Technical Electives / 18 / 18
Total =
/ 173 / 244
  1. University Requirements:
  1. Compulsory Courses:

Course No.

/

Course Title

/ Cr. Hr. / Lecture / Lab. / Prerequisite
or *Corequisite
ENGL098 / English I / 0 / 3 / 0
ENGL099 / English II / 0 / 3 / 0 / ENGL098
ENGL101 / English III / 1 / 3 / 0 / ENGL099
ENGL102 / English IV / 1 / 3 / 0 / ENGL101
ENGL201 / English V / 2 / 3 / 0 / ENGL102
ENGL202 / English VI / 2 / 3 / 0 / ENGL201
NE101 / National Education / 3 / 3 / 0
MILS100 / Military Science / 3 / 3 / 0
CS111 / Computing Fundamentals / 4 / 3 / 0
CS1110 / Computing Fundamentals Lab / 0 / 0 / 3
ARB099 / Arabic 99 / 0 / 3 / 0
ARB100 / Arabic / 3 / 3 / 0 / ARB099
GERL101 / German I / 3 / 9 / 0
GERL102 / German II / 3 / 9 / 0 / GERL101
GERL201 / German III / 3 / 6 / 0 / GERL102
GERL202 / German IV / 3 / 6 / 0 / GERL201
GERL301 / German V / 3 / 9 / 0 / GERL202
Total = / 34 / 72 / 3 / Contact Hrs. = 75

Ψ Student's score on the English Placement Test will decide the course level

  1. University Electives: 6 credit hours

Course No. / Course Title / Cr. Hr. / Lecture / Lab. / Prerequisite
or *Corequisite
DES 101 / Arts’ Appreciation / 3 / 3 / 0 / 
IC 101 / Intercultural Communications / 3 / 3 / 0 / 
SFTS 101 / Soft Skills / 3 / 3 / 0 / 
SE 301 / Social Entrepreneurship and Enterprises / 3 / 3 / 0 / 
EI 101 / Leadership and Emotional Intelligence / 3 / 3 / 0 / 
  1. School Requirements:

Course No.

/

Course Title

/ Cr. Hr. / Lecture / Lab. / Prerequisite
or *Corequisite

MATH 101

/

Calculus I

/ 3 / 3 / 0 / 

MATH 102

/ Calculus II / 3 / 3 / 0 /

MATH 101

MATH 201

/ Applied Mathematics for Engineers I / 3 / 3 / 0 /

MATH 102

MATH 231

/ Probability & Statistics for Engineering / 3 / 3 / 0 /

MATH 102

PHYS 101

/ Physics I / 4 / 3 / 3 / 

PHYS 102

/ Physics II / 4 / 3 / 3 /

PHYS 101

CHEM 101 / General Chemistry / 4 / 3 / 3 /

IE 121 / Workshop / 1 / 0 / 3 / 
IE 353 / Engineering Economics / 3 / 3 / 0 /

MATH 201

Total = / 28 / 24 / 12 / Contact Hrs. = 36
  1. Program Requirements

A minimum of 105 program credit hours are required for graduation divided into 87 credit hours as compulsory and 18 credit hours as technical electives.

  1. CompulsoryCourses

A total of 87 credit hours of corechemical-pharmaceutical engineering coursework are required for graduation, as follows.

Course No. / Course Title / Cr. Hr. / Lecture / Lab. / Prerequisite
or *Corequisite
CPE 212 / Microbiology / 4 / 3 / 3 / BIO 101
CPE 221 / Analytical Chemistry / 4 / 3 / 3 / CHEM101
CPE 226 / Physical Chemistry for Chemical/Pharmaceutical Engineers I / 3 / 3 / 0 / CHEM101 + MATH 102
CPE 228 / Physical Chemistry for Chemical/Pharmaceutical Engineers II / 4 / 3 / 3 / CPE 226
CPE 225 / Organic Chemistry / 4 / 3 / 3 / CHEM 101
CPE 233 / Introduction to Chemical/Pharmaceutical Engineering / 1 / 1 / 0 / CHEM 101
CPE 236 / Principles of Chemical Engineering / 3 / 3 / 0 / CPE 233 + * γCPE 228
CPE 238 / Fluid Mechanics for Chemical and Medical Engineers / 3 / 3 / 0 / MATH 201
CPE 324 / Instrumental Analysis / 4 / 3 / 3 / CPE 221
CPE 326 / Biochemistry / 4 / 3 / 3 / BIO 101+ CPE 225
CPE 331 / Transport Phenomena / 3 / 3 / 0 / CPE 236 + CPE 238
CPE 332 / Chemical Reaction Engineering I / 3 / 3 / - / CPE 236
CPE 334 / Chemical Reaction Engineering and Heat Transfer Lab / 1 / 0 / 3 / CPE 332 + CPE 331
CPE 336 / Separation Processes I / 3 / 3 / - / CPE 331
CPE 391 / Field Training Ψ / 0 / 0 / 160 h
CPE 435 / Pharmaceutical Technology – Liquid Forms / 4 / 3 / 3 / CPE 228 + CPE 238
CPE 436 / Pharmaceutical Technology – Solid Forms / 4 / 3 / 3 / CPE 331
CPE 437 / Separation Processes II / 3 / 3 / - / CPE 336
CPE 439 / Separation Processes Lab / 1 / 0 / 3 / CPE 336
CPE 499 / Practical Training / 12 / 0 / 6 months / DA
CPE 533 / Pharmaceutical Packaging Engineering / 3 / 3 / 0 / CPE 435 + CPE 436
CPE 536 / Pharmaceutical Facility Design / 3 / 3 / 0 / CPE 435 + CPE 436
CPE 595 / Graduation Project I / 3 / 0 / 9 / * γCPE 536
CPE 596 / Graduation Project II / 3 / 0 / 9 / CPE 595
BIO 101 / Biology / 3 / 3 / 0 /

ME 343 / Automatic Control Systems / 4 / 3 / 3 / MATH 201
87 / 58 / 51 / Contact Hrs. = 109

Ψ Students must complete 160 hours of field training in approved industries in Jordan by the end of their third academic year.

DA is Departmental Approval.

γ prerequisite or co-requisite

  1. Technical Electives

A minimum of 18 credit hours of specialized chemical-pharmaceutical engineering coursework are required for graduation. The offered courses are:

Course No. / Course Title / Cr. Hr. / Lecture / Lab. / Prerequisite
or *Corequisite
CPE 441 / Medicinal Chemistry / 3 / 3 / - / CPE 212 + CPE 326
CPE 451 / Biotechnology / 3 / 3 / - / CPE 332 + CPE 212
CPE 511 / Gene Technology / 3 / 3 / - / CPE 326
CPE 512 / Antibiotics / 3 / 3 / - / CPE 212
CPE 513 / Nutrition / 3 / 3 / - / BIO 101
CPE 524 / Introduction to Polymer Science / 3 / 3 /

CPE 225

CPE 527 / Pharmaceutical Organic Chemistry / 3 / 3 / - / CPE 225
CPE 526 / Colloids and Surface Chemistry / 3 / 3 / - / CPE 228 or DA
CPE 528 / Pharmaceutical Physical Chemistry / 3 / 3 / - / CPE 228
CPE 550 / Numerical Methods for Engineers / 3 / 3 / - / MATH 231
CPE 551 / Corrosion Engineering / 3 / 3 / - / CPE 228
CPE 552 / Nanotechnology / 3 / 3 / - / CPE 436
CPE 553 / Particle Technology / 3 / 3 / - / CPE 436
CPE 554 / Fluid Mixing Technology / 3 / 3 / - / CPE 238
CPE 555 / Chemical Process Safety / 3 / 3 / - / *CPE 536

CPE 556

/ Chemical Reaction Engineering II / 3 / 3 /

CPE 332

CPE 557 / Chemical & Physical Sensors / 3 / 3 / CPE 324 + CPE 326
CPE 558 / Environmental Engineering / 3 / 3 / CPE 221
CPE 559 / Membrane separation processes / 3 / 3 / CPE 336
CPE 561 / Experimental Design and Data Analysis / 3 / 3 / - / MATH 231
CPE 562 / Validation / 3 / 3 / - / MATH 231
CPE 563 / Pharmacokinetics / 3 / 3 / - / CPE 332 or DA
CPE 564 / Toxicology / 3 / 3 / - / CPE 326 or DA
CPE 565 / Modern Drug Forms & Delivery Systems / 3 / 3 / - / CPE 435
CPE 581 / Special Topics in Chemical /Pharmaceutical Engineering I / 3 / 3 / - / DA
CPE 582 / Special Topics in Chemical /Pharmaceutical Engineering II / 3 / 3 / - / DA
CPE 583 / Special Topics in Chemical /Pharmaceutical Engineering III / 3 / 3 / - / DA
CPE 584 / Special Topics in Chemical /Pharmaceutical Engineering IV / 3 / 3 / - / DA
CPE 585 / Special Topics in Chemical /Pharmaceutical Engineering V / 2 / 2 / - / DA
CPE 586 / Special Topics in Chemical /Pharmaceutical Engineering VI / 1 / 1 / - / DA
CPE 590 / Special Field Projects / 3 / - / 9 / DA
ENRE 431 / Renewable Energy Resources Assessment / 3 / 3 / - / ENRE 331 or DA
ENRE 436 / Energy Management / 3 / 3 / - / IE 531 or DA
IE 531 / Project Management / 3 / 3 / - / IE 353
WEEM 453 / Wastewater Engineering / 3 / 3 / - / WEEM 351 or DA
WEEM 473 / Emission Control / 3 / 3 / - / WEEM 271 or DA
WEEM 522 / Hazardous Waste Management / 3 / 3 / - / WEEM 231 or DA

DA is Departmental Approval.

Number Code: CPE XYZ

X:Course Level: “1” is year 1, “5” is year 5.

Y:Subject of the course; defined as follows:

1Biology

2Chemistry

3Chemical Engineering- Core course

5Chemical Engineering- Elective course

4Pharmaceutical Engineering- Core course

6Pharmaceutical Engineering- Elective course

8Special Topics

9Projects.

Z:“odd #” means first semester; “even #” means second semester.
Guide Plan for Chemical/Pharmaceutical Engineering Program

Year 1 – Semester 1
Course I.D. / Course Title / Credit Hours / Contact Hours / Prerequisite *Co-requisite
Lecture / Practical
GERL 101 / German I / 3 / 9 / 0 / 
ENGL 101 / English III / 1 / 3 / 0 / ENGL 099
CHEM 101 / General Chemistry / 4 / 3 / 3 / 
MATH 101 / Calculus I / 3 / 3 / 0 / 
PHYS 101 / Physics I / 4 / 3 / 3 / 
ARB 100 / Arabic / 3 / 3 / 0 / 
Total / 18 / 24 / 6 / Contact Hrs. = 30
Year 1 – Semester 2
Course I.D. / Course Title / Credit Hours / Contact Hours / Prerequisite *Co-requisite
Lecture / Practical
GERL 102 / German II / 3 / 9 / 0 / GERL 101
ENGL 102 / English IV / 1 / 3 / 0 / ENGL 101
MATH 102 / Calculus II / 3 / 3 / 0 / MATH 101
PHYS 102 / Physics II / 4 / 3 / 3 / PHYS 101
BIO 101 / Biology / 3 / 3 / 0 / 
CS 111 / Computing Fundamentals / 4 / 3 / 0 / *CS 1110
CS 1110 / Computing Fundamentals Lab / 0 / 0 / 3 / *CS 111
Total / 18 / 24 / 6 / Contact Hrs. = 30
Year 2 – Semester 1
Course I.D. / Course Title / Credit Hours / Contact Hours / Prerequisite *Co-requisite
Lecture / Practical
GERL 201 / German III / 3 / 6 / 0 / GERL 102
ENGL 201 / English V / 2 / 3 / 0 / ENGL 102
MATH 201 / Applied Mathematics for Engineers I / 3 / 3 / 0 / MATH 102
CPE 226 / Physical Chemistry for Chemical/Pharmaceutical Engineers I / 3 / 3 / 0 / CHEM 101 + MATH 102
CPE 225 / Organic Chemistry / 4 / 3 / 3 / CHEM 101
CPE 233 / Introduction to Chemical/Pharma Eng / 1 / 1 / 0 / CHEM 101
IE 121 / Workshop / 1 / 0 / 3 / 
Univ. ??? / University Elective I / 3 / 3 / 0 / 
Total / 20 / 22 / 6 / Contact Hrs. = 28
Year 2 – Semester 2
Course I.D. / Course Title / Credit Hours / Contact Hours / Prerequisite /
*Co-requisite
Lecture / Practical
GERL 202 / German IV / 3 / 6 / 0 / GERL201
ENGL 202 / English VI / 2 / 3 / 0 / ENGL 201
CPE 212 / Microbiology / 4 / 3 / 3 / BIO 101
CPE 228 / Physical Chemistry for Chemical/Pharmaceutical Engineers II / 4 / 3 / 3 / CPE 226
CPE 236 / Principles of Chemical Engineering / 3 / 3 / 0 / CPE 233 +*ϒCPE 228
CPE 238 / Fluid Mechanics for Chemical and Medical Engineers / 3 / 3 / 0 / MATH 201
Total / 19 / 21 / 6 / Contact Hrs. = 27
Year 3 – Semester 1
Course I.D. / Course Title / Credit Hours / Contact Hours / Prerequisite /
*Co-requisite
Lecture / Practical
GERL 301 / German V / 3 / 9 / 0 / GERL 202
MATH 231 / Probability & Statistics for Engineers / 3 / 3 / 0 / MATH 102
CPE 221 / Analytical Chemistry / 4 / 3 / 3 / CHEM 101
CPE 331 / Transport Phenomena / 3 / 3 / 0 / CPE 236 + CPE 238
CPE 332 / Chemical Reaction Engineering I / 3 / 3 / 0 / CPE 236
CPE 391 / Field Training / 0 / 0 / - / 
CPE 435 / Pharmaceutical Technology  Liquid Forms / 4 / 3 / 3 / CPE 228 + CPE 238
Total / 20 / 24 / 6 / Contact Hrs. = 30

Students must complete 160 hours of field training in approved industries in Jordan by the end of third academic year.

Year 3 – Semester 2
Course I.D. / Course Title / Credit Hours / Contact Hours / Prerequisite /
*Co-requisite
Lecture / Practical
CPE 324 / Instrumental Analysis / 4 / 3 / 3 / CPE 221
CPE 326 / Biochemistry / 4 / 3 / 3 / BIO 101 + CPE 225
CPE 334 / Chemical Reaction Eng. & Heat Transfer Lab / 1 / 0 / 3 / CPE 332 + CPE 331
CPE 336 / Separation Processes I / 3 / 3 / 0 / CPE 331
CPE 436 / Pharmaceutical Technology  Solid Forms / 4 / 3 / 3 / CPE 331
IE 353 / Engineering Economics / 3 / 3 / 0 / MATH 201
Total / 19 / 15 / 12 / Contact Hrs. = 27
Year 4 – Semester 1 & 2
Course I.D. / Course Title / Credit Hours / Contact Hours / Prerequisite /
*Co-requisite
Lecture / Practical
Technical Elective I / 3 / 3 / 
Technical Elective II / 3 / 3 / 
Technical Elective III / 3 / 3 / 
Technical Elective IV / 3 / 3 / 
CPE 499 / Practical Training / 12 /  / 6 months
Total / 24 / 12 / 6 months / Contact Hrs. = 12
Year 5 – Semester 1
Course I.D. / Course Title / Credit Hours / Contact Hours / Prerequisite /
*Co-requisite
Lecture / Practical
CPE 439 / Separation Processes Lab / 1 / 0 / 3 / CPE 336
CPE 437 / Separation Processes II / 3 / 3 / 0 / CPE 336
CPE 533 / Pharmaceutical Packaging Engineering / 3 / 3 / 0 / CPE 435 + CPE 436
CPE 536 / Pharmaceutical Facility Design / 3 / 3 / 0 / CPE 435 + CPE 436
CPE 595 / Graduation Project I / 3 / 0 / 9 / *CPE 536
CPE ??? / Technical Elective V / 3 / 3 / 0
Univ. ??? / University Elective II / 3 / 3 / 0 / 
Total / 19 / 15 / 12 / Contact Hrs. = 27
Year 5 – Semester 2
Course I.D. / Course Title / Credit Hours / Contact Hours / Prerequisite /
*Co-requisite
Lecture / Practical
CPE 596 / Graduation Project II / 3 / 0 / 9 / CPE 595
CPE ??? / Technical Elective VI / 3 / 3 / 0
ME 343 / Automatic Control Systems / 4 / 3 / 3 / MATH 201
NE 101 / National Education / 3 / 3 / 0 / 
MILS 100 / Military Science / 3 / 3 / 0 / 
Total / 16 / 12 / 12 / Contact Hrs. = 24

1

1

Course Description for the Chemical-Pharmaceutical Engineering Program

ARB 100: Arabic (3 Cr. Hrs.)

Grammar and structure. Rectifying weakness in linguistic application; training in sound reading. Dictation; use of language in a manner free from grammatical and linguistic errors; accurate expression of intended meaning. Study and analysis of literary texts through the discussion of linguistic, grammatical and writing skills therein

BIO 101. Biology. (3 Cr. Hrs.) Two lectures per week.

Prerequisites: none

Cell biology (construction, transport through membranes, metabolism), photosynthesis, genetics, proteins, enzymes, protein synthesis and finally dealing with the human systems including: Muscular system, bones-skeletal system-, digestive, respiratory, nervous, immunity, endocrine, circulatory-heart- and the urinary system.

CHEM 101. General Chemistry.(4 Cr. Hrs.) Two lectures per week and 3 hours of laboratory.

Prerequisites: none.

Stoichiometry of formulas and equations. Gases and the kinetic-molecular theory. Quantum theory and atomic structure. The components of matter. The major classes of chemical reactions (precipitation, acid-base, oxidation-reduction, and reversible reactions). Thermodynamics: energy flow and chemical change. Quantum theory and atomic structure. Electron configurations and chemical periodicity. Kinetics: rates and mechanisms of chemical reactions. Equilibrium: The extent of chemical reactions. Acid-base equilibria.

CPE 212. Microbiology. (4 Cr. Hrs.) Two lectures per week and 3 hours of laboratory.

Prerequisites: Biology (BIO 101)

Microbiological diagnostics, medical and clinical aspects of microbiology. The need for sterilization and disinfection in hospitals and laboratories. Taxonomy of bacteria. In addition to the importance of bacteria as causative agents of infections and their use in biotechnology.

CPE 221. Analytical Chemistry. (4 Cr. Hrs.) Two lectures per week and 3 hours of laboratory.

Prerequisites: General Chemistry (CHEM 101).

Acid-base equilibria. Redox equilibria. Complex-formation equilibria. Electrolytes, electrolytic dissociation – conductivity of aqueous solutions, conductometry, ionic mobility, Hittorf’s ion transference numbers, electrochemical potential (metals and non-metals, organic compounds), Nernst’s law, fundamentals of potentiometric instrumentation, fundamentals of voltametry (current-voltage curves), Karl-Fischer titration.

CPE 226. Physical Chemistry for Chemical/Pharmaceutical Engineers I. (3 Cr. Hrs.) Two lectures per week.

Prerequisites: General Chemistry (CHEM 101,) and Calculus II (MATH 102).

Behavior of gases. Equations of state and real gases. The first law of thermodynamics. The second and third laws of thermodynamics. Chemical equilibrium. Phases and solutions.

CPE 228. Physical Chemistry for Chemical/Pharmaceutical Engineers II. (4 Cr. Hrs) Two lectures per week and 3 hours of laboratory.

Prerequisites: Physical Chemistry for Chemical/Pharmaceutical Engineers II (CPE 226).

Phase equilibria. Solutions of electrolytes. Thermodynamics of ions. Electrochemical cells. The solid state: crystals forms and structures. Surface chemistry and colloids.

CPE 225. Organic Chemistry. (4 Cr. Hrs.) Two lectures per week and 3 hours of laboratory.

Prerequisites: General Chemistry (CHEM 101).

Bonding models for CH, simple CC and multiple CC bonds. The possibilities for isomery of open-chained cyclic hydrocarbons including their dynamics (conformation). Electron structure of conjugated double bonds and aromatic π-systems. Polar single and multiple bonds and the resulting electronic substituent effects. The most important classes of organic compounds. Overview of various reaction types and initial mechanistic reaction observations.

CPE 233. Intr. to Chemical/Pharmaceutical Engineering. (1 Cr. Hr.) One lecture per week.

Prerequisites: General Chemistry (CHEM 101)

What chemical/pharmaceutical engineers do. Engineering calculations: units, dimensional homogeneity and dimensionless quantities. Process data presentation and analysis. Processes and process variables.

CPE 236. Principles of Chemical Engineering. (3 Cr. Hrs.) Two lectures per week.

Prerequisites: Introduction to Chemical/Pharmaceutical Engineering (CPE 233)

Corequisite: Physical Chemistry for Chemical/Pharmaceutical Engineers II (CPE 228)

Fundamentals of material and energy balances. Single and multiphase systems. Balances on nonreactive and reactive processes.

CPE 238. Fluid Mechanics for Chemical and Medical Engineers. (3 Cr. Hrs.) Two lectures per week.

Prerequisites: Applied Mathematics for Engineers I (MATH 201).

Fluid mechanics in chemical engineering. Density, viscosity and surface tension. Mass, energy and momentum balances. Bernoulli’s equation. Fluid friction in pipes. Flow in engineering equipment: pumps and compressors. Forces on solid particles in fluids. Flow through packed beds, filtration, fluidization. Dimensional analysis. Differential equations of fluid mechanics. Turbulent flow.

CPE 324. InstrumentalAnalysis. (4 Cr. Hrs.) Two lecture per week and 3 hours of laboratory.

Prerequisites: Analytical Chemistry (CPE 221).

Electrical components and circuits. Signals and noise. Atomic Spectrometry: flame technology, graphite furnace technology, cold vapor and hydride technology, inductively coupled plasma. UV Spectroscopy. IR Spectroscopy. Raman Spectroscopy. Mass spectroscopy. Chromatographic Methods: Fundamentals of chromatographic analysis. High performance liquid chromatography.Gas chromatography. Capillary electrophoresis. Sample preparation techniques for chromatographic analyses. Thermogravimetric Analysis and DSC analyses. Eutectic systems. Glass transition temperature. Crystallography. X-ray diffractometry. Electrical, optical and magnetic properties of crystalline substances. Surface characterization by spectroscopy and microscopy: Basic introduction to scanning electron microscopy, scanning tunneling microscopy, atomic force microscopy and near-field optical microscopy, probe types and work methods.

CPE 326. Biochemistry. (4 Cr. Hrs.) Two lectures per week and 3 hours of laboratory.

Prerequisites: Organic Chemistry (CPE 225), Biology (BIO 101).

Amino acids and peptides; Proteins: structure and function. Enzymes, enzyme kinetics of carbohydrates. Lipids, biological membranes. Nucleic acids; replication, transcription, translation. Biosynthesis of protein. Bioenergetics. Primary metabolism and regulation.

CPE 331. Transport Phenomena. (3 Cr. Hrs.) Two lectures per week.

Prerequisites: Principles of Chemical Engineering (CPE 236), and Fluid Mechanics for Chemical Engineers (CPE 238).

Introduction to mass transfer. Diffusion fluxes and Fick’s law. Transport properties of mixtures. The general problem of heat transfer. Modes of heat transfer. Heat conduction concepts. Heat exchanger design. Steady and transient heat conduction. Convective heat transfer in laminar and turbulent systems. Simultaneous heat and mass transfer.

CPE 332. Chemical Reaction Engineering I. (3 Cr. Hrs.) Two lectures per week.

Prerequisites: Principles of Chemical Engineering (CPE 231)

Kinetics of homogeneous reactions. Prediction of rates of chemical conversion. Reactor design for single and multiple reactions. Michaelis-Menten kinetics. Retention time in chemical reactors. Design for heterogeneous reacting systems. Solid-catalyzed reactions.

CPE 334. Chemical Reaction Engineering and Heat Transfer Lab. (1 Cr. Hr). Three hours of laboratory per week.

Prerequisites: Chemical Reaction Engineering I (CPE 332), and Transport Phenomena (CPE 331)

Conduct experiments applying chemical engineering and heat transfer concepts.

CPE 336. Separation Processes I. (3 Cr. Hrs.) Two lectures per week and 3 hours of laboratory.

Prerequisites: Transport Phenomena(CPE 331).

Stage and continuous gas-liquid separation processes. Vapor-liquid separation processes: absorption and stripping, distillation.Drying of process materials.

CPE 435. Pharmaceutical Technology  Liquid Forms. (4 Cr. Hrs.) Two lectures per week and 3 hours of laboratory.

Prerequisites: Physical Chemistry for Chemical/Pharmaceutical Engineers II (CPE 228), andFluid Mechanics for Chemical Engineers (CPE 238).

Water systems and purification. Liquid dosage forms (solutions, suspensions, emulsions, sterile/parenteral dosage forms). Filling and Packaging. Microbiological contamination. Types of semisolid topical dosage forms (Gels, ointments, creams, pastes), suppositories and pessaries, suppositories and pessaries, transdermal patches, intrauterine and intravaginal therapeutic systems, therapeutic aerosols.

CPE 436. Pharmaceutical Technology  Solid Forms. (4 Cr. Hrs.) Two lectures per week and 3 hours of laboratory.

Prerequisite: Transport Phenomena(CPE 331).

Particle size reduction, powder mixing, granulation and pellitization, drying, tableting, coating, hard and soft capsules, microparticles, implants; milling, sieving, sifting, mixing solid substances, granulating, tableting, film-coating. Testing of powders, granulates, tablets, capsules, microparticles and implants.

CPE 437. Separation Processes II. (3 Cr. Hrs.) Two lectures per week and 3 hours of laboratory.

Prerequisites: Separation Processes I (CPE 336).

Liquid-liquid extraction, adsorption, membrane separation, leaching, crystallization and evaporation.

CPE 439. Separation Processes Lab. (1 Cr. Hrs.) Three hours of laboratory per week.

Prerequisites: Transport Phenomena (CPE 336).

Conduct experiments applying separation processes concepts.

CPE 441. Medicinal Chemistry. (3 Cr. Hrs.) Two lectures per week.

Prerequisites: Microbiology (CPE 212), and Biochemistry (CPE 326).

Pharmaceutical Chemistry: drugs and their interactions, principles of finding drugs, inorganic agents, organic agents - ordered according to therapy groups: nervous system, endocrine system, substances that affect the heart and circulatory system, respiratory tract, skin and vitamins and chemo-therapeutics. Pharmaceutical Biology: herbal substances, technology of herbal drugs, testing the intermediate products and the final drug in accordance with national and international pharmacopoeias. Pharmacology:Introduction to pharmacology: pharmacodynamics, pharmacokinetics. Effect of drugs on the human organism.

CPE 451. Biotechnology. (3 Cr. Hrs.) Two lectures per week.

Prerequisites:Chemical Reaction Engineering I (CPE 332),and Microbiology (CPE 212).

The tasks of biotechnology in the pharmaceutical industry, agriculture, food industry. Biotechnological methods and processes. Fermentation process and reactors. Processing of biotechnological products for applications from intra and extra cellular products to packaging. What are enzymes, their biotechnological production, their applications in medicine, diagnostics, food production, pharmacy, agriculture and research. Biotechnological production of biomass, low molecular weight products and macromolecules and also biotransformations.

CPE 499. Practical Training. (12 Cr. Hrs.)

Prerequisites: Departmental Approval.

Practical training for 18 weeks after the completion of at least 90 credit hours (See Practical Training Regulations of the College of Applied Medical Sciences).

CPE 511. Gene Technology. (3 Cr. Hrs.) Two lectures per week.

Prerequisites: Biochemistry (CPE 326).

Introduction; transfer of genetic information into proteins: transcription/ translation; tools of the genetic engineer; host organisms and properties; cloning; polymerase chain reaction; applications in genetic engineering.

CPE 512. Antibiotics. (3 Cr. Hrs.) Two lectures per week.

Prerequisites: Microbiology (CPE 212).

Introduction to antibiotics and antibacterial chemotherapy. Classification and structure-activity relationship of antibiotics and antibacterial agents. Epidemiology of resistance to antibacterial agents. Development of an antibiotic. Inhibitors of ß-lactamases, DNA-gyrase. Codrugs. Coumarin antibiotics. Development of resistance and the use of multiple antibacterials during an infection. Drug interactions. Antibacterials and bioterrorism. Clinical quality assurance and the international development of new anti-infective agents.