Supplement Table 2. Univariate survival analysis of variables for time-period 1 (1991-2000).

Factor / Number / Survival rate, % / Survival, median (95% CI) / HR (95% CI) / P value
No. / deaths / 12 mo / 24 mo
Gender
Men / 94 / 84 / 60 / 28 / 14 (12-17) / 1 / 0.404
Women / 85 / 78 / 72 / 34 / 21 (16-25) / 0.9 (0.6-1.2)
Age (per year) / - / - / - / - / - / 1 (0.9-1) / 0.134
Size (per cm) / - / - / - / - / - / 1.2 (1.1-1.4) / 0.004
Lymph nodes
Negative / 75 / 62 / 70 / 38 / 22 (17-29) / 1 / 0.009
Positive / 104 / 99 / 63 / 16 / 14 (13-18) / 1.5 (1.1-2.1)
Resection margins
Negative / 154 / 137 / 67 / 49 / 22 (17-29) / 1 / 0.074
Positive / 25 / 24 / 60 / 24 / 14 (13-18) / 1.5 (0.9-2.3)
Type of operation
Distal pancreatectomy / 7 / 3 / 86 / 71 / 21 (16.1-NA) / 1 / 0.0126
Whipple / 160 / 147 / 69 / 35 / 16.9 (14.8-21) / 4.3 (1.36-13.6)
Tumor grade
Well differentiated / 29 / 21 / 82 / 63 / 29 (24-116) / 1 / 0.003
Moderately differentiated / 115 / 105 / 68 / 31 / 16 (18-19) / 1.9 (1.2-3.2)
Poorly differentiated / 35 / 33 / 46 / 25 / 8 (9-20) / 2.5 (1.4-4.3)
Treatment
No adjuvant therapy / 98 / 99 / 63 / 30 / 15 (14-20) / 1 / 0.049
Adjuvant therapy / 53 / 46 / 77 / 45 / 22 (18-29) / 0.7 (0.5-0.9)
LVI
No LVI / 104 / 93 / 64 / 36 / 15 (13-22) / 1 / 0.539
LVI / 27 / 26 / 67 / 22 / 17 (15-21) / 1.2 (0.8-1.8)
PNI
No PNI / 87 / 79 / 62 / 30 / 14 (13-18) / 1 / 0.747
PNI / 59 / 54 / 71 / 34 / 17 (15-23) / 0.9 (0.7-1.3)
Tumor stage
I / 26 / 19 / 73 / 54 / 26 (16-NA) / 1 / 0.03
IIa / 44 / 40 / 68 / 46 / 22 (17-31) / 1.4 (0.8-2.4)
IIb / 102 / 97 / 62 / 26 / 14 (13-17) / 1.9 (1.2-3.2)
III / 7 / 6 / 71 / 29 / 14 (9.2-NA) / 1.7 (0.7-4.2)

Supplement Table 2. Analyses performed on n=167. Patients who died during the perioperative period were excluded from the analysis (n=12). HR: Hazards Ratio; 95% CI: 95% Confidence Interval; LVI: lymphovascular invasion; PNI: perineural invasion. Bolding indicateP<0.05.