Supplementary Table 1: Annual, surface-area adjusted incidence of invasive cutaneous melanoma (confirmed SSM and NM only) by age and anatomical site in West of Scotland and Queensland 1982-2001. Males.

Age < 40 years / Age 40-59 years / Age 60 years
Anatomical site / WoS1 / QLD2 / IRR5 / WoS / QLD / IRR / WoS / QLD / IRR
Head & Neck / SA-ASR4 / 2.36 / 14.6 / 6.2 / 8.88 / 68.5 / 7.7 / 48.8 / 215 / 4.4
Trunk / SA-ASR / 3.16 / 17.0 / 5.4 / 14.5 / 83.6 / 5.8 / 19.1 / 154 / 8.1
Upper limb / SA-ASR / 2.00 / 11.4 / 5.7 / 6.47 / 58.1 / 9.0 / 8.74 / 144 / 16.5
Lower limb / SA-ASR / 1.33 / 5.40 / 4.1 / 4.05 / 22.0 / 5.4 / 5.35 / 36.0 / 6.7
All sites / ASR / 2.14 / 11.5 / 5.4 / 8.29 / 54.5 / 6.6 / 14.3 / 113 / 7.9

1 West of Scotland

2Queensland

3 Surface-area adjusted, age standardised rate of melanoma (European population) per 100,000 person-years at risk

4 Incidence rate ratio (Queensland: Scotland)

Supplementary Table 2: Annual, surface-area adjusted incidence of invasive cutaneous melanoma (confirmed SSM and NM only) by age and anatomical site in West of Scotland and Queensland 1982-2001. Females.

Age < 40 years / Age 40-59 years / Age 60 years
Anatomical site / WoS1 / QLD2 / IRR4 / WoS / QLD / IRR / WoS / QLD / IRR
Head & Neck / SA-ASR3 / 3.15 / 12.70 / 4.0 / 9.10 / 36.63 / 4.0 / 33.15 / 106.74 / 3.2
Trunk / SA-ASR / 2.81 / 15.06 / 5.4 / 6.50 / 38.06 / 5.9 / 4.00 / 28.13 / 7.0
Upper limb / SA-ASR / 3.79 / 18.16 / 4.8 / 11.79 / 70.74 / 6.0 / 16.68 / 98.42 / 5.9
Lower limb / SA-ASR / 5.18 / 11.38 / 2.2 / 17.05 / 44.25 / 2.6 / 18.60 / 54.50 / 2.9
All sites / ASR / 3.98 / 14.5 / 3.6 / 12.09 / 48.5 / 4.0 / 15.3 / 60.9 / 4.0

1 West of Scotland

2Queensland

3 Surface-area adjusted, age standardised rate of melanoma (European population) per 100,000 person-years at risk

4 Incidence rate ratio (Queensland: Scotland)

Supplementary Table 3: Observed-to-expected ratios for melanoma incidence (confirmed SSM and NM only) in the West of Scotland 1982-2001, by sex, age group and anatomical site

Males / Females
O/E / 95% CI / O/E / 95% CI
Age, Sex and Site
<40 years
Head and neck
Trunk
Upper limb
Lower limb / 0.85
0.96
0.91
1.28 / (0.60 – 1.20)
(0.85 – 1.09)
(0.71 – 1.17)
(1.04 – 1.57) / 0.87
0.66
0.73
1.60 / (0.63 – 1.19)
(0.56 – 0.77)
(0.61 – 0.87)
(1.46 – 1.76)
Homogeneity 2 (3 d.f.) / 7.1 / NS / 122.5 / P<0.001
40-59 years
Head and neck
Trunk
Upper limb
Lower limb / 0.82
1.11
0.70
1.18 / (0.55 – 1.20)
(0.95 – 1.29)
(0.53 – 0.94)
(0.88 – 1.57) / 0.95
0.67
0.67
1.55 / (0.71 – 1.27)
(0.57 – 0.79)
(0.57 – 0.78)
(1.44 – 1.67)
Homogeneity 2 (3 d.f.): / 19.5 / p < 0.001 / 112.6 / p < 0.001
>60 years
Head and neck
Trunk
Upper limb
Lower limb / 1.77
0.95
0.47
1.15 / (1.40 – 2.25)
(0.81 – 1.11)
(0.36 – 0.62)
(0.85 – 1.56) / 1.21
0.56
0.67
1.35 / (0.90 – 1.64)
(0.40 – 0.80)
(0.53 – 0.84)
(1.11 – 1.62)
Homogeneity 2 (3 d.f.): / 14.0 / p < 0.001 / 33.7 / p < 0.001

1 Ratio of observed to expected number of melanomas in the west of Scotland population, assuming the same anatomical distribution of melanomas within each category of sex and age as the Queensland population. Expected numbers of melanomas have been scaled in each category to account for the difference in magnitude of melanoma incidence between Scotland and Queensland (see text for details).

Supplementary Figure 1: Area-adjusted age-standardised incidence of melanoma in West of Scotland and Queensland 1982-2001. Males

Incidence of melanoma is age-standardized to the European standard population and adjusted for the relative surface are of each anatomical site.

Supplementary Figure 2: Area-adjusted age-standardised incidence of melanoma in West of Scotland and Queensland 1982-2001. Females

Incidence of melanoma is age-standardized to the European standard population and adjusted for the relative surface are of each anatomical site.