Appendix (E)A-1Screening questionnaire I for Cluster Headache (N=25,480)

Affirmative response, %
Question / Men / Women / All
I will now ask questions on another area.
1Have you or have you had recurrent headache that has not been associated with infections, fever or hangover? / 18.4%
[2,227/12,115] / 33.0%†
[4,416/13,365] / 26.1%
[6,643/25,480]
I will now ask questions on three different types of headache. We start with the first type.
2Have you or have you had attacks of *severe* or *very severe* ache in the region of one eye or one temple? / 37.0%
[823/2,227] / 52.5%†
[2,319/4,416] / 47.3%
[3,142/6,643]
On the following questions I want you to think on these *severe* or *very severe* attacks in the region of one eye or temple.
3Did the ache always appear on the same side of the head? / 65.2%
[537/823] / 64.1%
[1,486/2,319] / 64.4%
[2,023/3,142]
4If you did *not* take any medication against the ache, did it last everything from 15 minutes to the maximum of 3 hours? / 59.8%
[492/823] / 51.6%†
[1,196/2,319] / 53.7%
[1,688/3,142]
Now I will ask questions on how often you have had these *severe* or *very severe* headache attacks.
5When you have had this headache did the attacks occur two times per week or more? ‡ / 30.7(+1.5)%
[253(+12)/823] / 19.4(+2.2)%†
[449(+52)/2,318] / 22.4(+2.0)%
[702(+64)/3,141]
6Did the attacks occur on almost every single day? / 51.0%
[129/253] / 41.9%
[188/449] / 45.2%
[317/702]
7 Did the attacks occur from 1 up to 8 times per day? / 71.3%
[92/129] / 60.1%
[113/188] / 64.7%
[205/317]
8Have you had these headache attacks during *periods* lasting a few weeks or more? / 67.2%
[178/265] / 56.1%†
[281/501] / 59.9%
[459/766]
9Have these headache attacks recurred regularly during *one year* or so or even longer? / 57.0%
[151/265] / 69.7%†
[349/501] / 65.3%
[500/766]
10Did one or several of the following symptoms appear during the attack: stuffiness of the nostril, running nose, tearing, red eye, or hanging eye lid? / 44.2%
[117/265] / 44.1%
[221/501] / 44.1%
[338/766]
Have you or have you had one or *several* of the following types of headache?
11Cluster headache? / 4.0%
[90/2,227] / 1.6%†
[71/4,415] / 2.4%
[161/6,642]

† Men vs. Women, p<0.05 (adjustment for multiple comparison); ‡ Subjects answering “do not know” are depicted between the parentheses (these persons were also eligible for the follow-up questions on periods, regular attacks during one year, and local autonomic symptoms)

Possible CH: [1, 2, 4, 6, 8, 10] (“algorithm”);[1, 11] (“self-report”)