Curriculum Vitae
Name: Mariam Anees
Date of Birth: 16.12.1983
Nationality: Pakistani
Marital Status: Married
Address: Department of Biochemistry, Quaid-i-Azam University, Islamabad
Telephone: (Cell) +92-333-5348160; (Off) +92-51-90643224; (Res) +92-51-5732098
Email: ,
Career Objective
To remain embarked on the challenging field of biochemistry/molecular biology in organizations and institutions where experience can be leveraged, knowledge and skills can be enhanced and humanity can be served in best possible way.
Education
Ph.D. (Molecular Biology) 2012
Medical University of Vienna, Vienna, Austria
M. Phil. (Endocrinology) 2007
Quaid-e-Azam University, Islamabad, Pakistan
M.Sc. (Biochemistry/Molecular Biology) 2005
Quaid-e-Azam University, Islamabad, Pakistan
B.Sc. (Zoology, Botany, Chemistry) 2003
University of the Punjab, Lahore, Pakistan
Higher Secondary School Certificate (Pre-Medical) 2001
FBISE, Islamabad, Pakistan
Secondary School Certificate (Science) 1999
FBISE, Islamabad, Pakistan
Awards/Distinctions
· Winner of the “Austrian Life Science Award” (2010) along with a 10,000 Euro cash prize for best scientific publication by a young scientist.
· Higher Education Commission Pakistan Merit scholarship for Ph.D. studies in Austria.
· Quaid-i-Azam University Merit Scholarship for M .Phil. studies.
· Roll of Honour in Graduation with College Top in Zoology and Botany subjects.
Work Experience
· Assistant Professor – Department of Biochemistry, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan. Sept 2012 – Present
· Visiting Faculty –Community Health and Nutrition Program (M.Sc.), Allama Iqbal Open University, Islamabad, Pakistan. Sept 2005 – Feb 2007
Additional Responsibilities
· Current ‘Advisor’ of Biochemists Association of Quaid-i-Azam University Islamabad (BAQI).
· Current ‘Student Affairs In-charge’ of the Department of Biochemistry, Quaid-i-Azam University, Islamabad, Pakistan.
· Current ‘Member’ of the Admission and Scholarship Committees of the Department of Biochemistry, Quaid-i-Azam University, Islamabad, Pakistan.
· Current ‘Executive Council Member’ of the Academic Staff Association of Quaid-i-Azam University, Islamabad, Pakistan, 2012-13
· Served as ‘Joint Secretary’ of the Academic Staff Association of Quaid-i-Azam University, Islamabad, Pakistan, 2013-14.
· Served as the ‘Executive Council Member’ of the Academic Staff Association of Quaid-i-Azam University, Islamabad, Pakistan, 2012-13.
· Served as ‘Conference Secretary’ of the International Conference on the Applications of Molecular Biology in Medicine and Agriculture, August 20-22, 2013.
Research Publications
1. Effect of Maternal Iodine Supplementation on Thyroid Function and Birth Outcome in Goiter Endemic Areas. Anees M, Anis RA, Yousaf S, Murtaza I, Sultan A, Arslan M, Shahab M (2015) Current Medical Research and Opinion – In Press.
2. Clinical Role of HER2 gene Amplification and chromosome 17: A cohort Study on 154 Immunohistochemically-Equivocal Cases of Pakistani Invasive Breast Carcinoma Patients. Murtaza I, Anees M, Sultan A (2015) Tumor Biology – In Press.
3. The potential evasion of immune surveillance in MALT lymphoma by DcR2-mediated upregulation of NF-ĸB. Anees M, Horak P, Schiefer AI, Perco P, Vanhara P, El-Gazzar A, Müllauer L, Streubel B, Raderer M, Krainer M (2014) Leukemia and Lymphoma 5:1-10.
4. TUSC3 Loss Alters the ER Stress Response and Accelerates Prostate Cancer Growth in vivo.
Horak P, Tomasich E, Vanhara P, Kratochvilova K, Anees M, Marhold M, Lemberger C, Gerschpacher M, Horvat R, Sibilia M, Pils D, Krainer M (2014) Scientific Reports 4:3739.
5. UNHCR Nutrition Survey in Afghan Refugee Villages of Pakistan (2014) A collaborative project of SoSec and UNHCR.
6. Loss of the oligosaccharyl transferase subunit TUSC3 promotes proliferation and migration of ovarian cancer cells. Vaňhara P, Horak P, Pils D, Anees M, Petz M, Gregor W, Zeillinger R, Krainer M (2013) International Journal of Oncology 42(4):1383-9.
7. Methylation status of TUSC3 is a prognostic factor in ovarian cancer. Pils D, Horak P, Vanhara P, Anees M, Petz M, Alfanz A, Gugerell A, Wittinger M, Gleiss A, Auner V, Cacsire-castillo D, Zeillinger R, Ioana Braicu E, Sehouli J, Krainer M (2013) Cancer 119(5):946-54.
8. Education and Training in Transfusion Medicine: A Case of Pakistan. Zaheer HA, Waheed U, Anees M (2013) SAARC Journal of Human Resource Development, ISSN 1816-4366, 9(1)101-107.
9. Study of the effect of 26RF- and 43RF-amides on Testosterone and Prolactin secretion in the adult male rhesus monkey (Macaca mulatta). Wahab F, Salahuddin H, Anees M, Leprince J, Vaudry H, Tena-Sempere M, Shahab M (2012) Peptides 36(1):23-8.
10. Human Development in South Asia 2012 Governance for People’s Empowerment. Anees M, Khan RW (2012) SAARC Journal of Human Resource Development, ISSN 1816-4366, 8(1):119-125.
11. Nutrition Baseline Survey in 11 Districts of KPK and Balochistan (2012) A collaborative project of SoSec, UNICEF, WHO, WFP and AusAID along with Provincial Health Ministries.
12. hVp37A status determines prognosis and cetuximab sensitivity in ovarian cancer. Wittinger M, Vanhara P, El-Gazzar A, Brenner B, Pils D, Anees M, Grunt TW, Sibilia M, Holcmann M, Horvat R, Schemper M, Zeillinger R, Schoefer C, Dolznig H, Horak P, Krainer M (2011) Clinical Cancer Research 17(24):7816-27.
13. Recurrence free survival in prostate cancer is related to increased stromal TRAIL expression. Anees M, Horak P, El-Gazzar A, Susani M, Heinze G, Perco P, Pangerl T, Loda M, Lis R, Krainer M, Oh WK (2011) Cancer 117(6):1172-82.
14. Natural Immunity Enhances the Activity of a DR5 Agonistic Antibody and Carboplatin in the Treatment of Ovarian Cancer. El-Gazzar A, Perco P, Eckelhart E, Anees M, Sexl V, Mayer B, Liu Y, Mikulits W, Horvat R, Pangerl T, Zheng D, Krainer M (2010) Molecular Cancer Therapeutics 9(4):1007-18.
15. The role of c-FLIPL in ovarian cancer: Chaperoning tumor cells from immunosurveillance and increasing their invasive potential. El-Gazzar A, Wittinger M, Perco P, Anees M, Horvat R, Mikulits W, Grunt TW, Mayer B, Krainer M (2010) Gynecologic Oncology 117(3):451-9.
16. Dietary Assessment with Reference to Iron Fortified Wheat Flour among Child Bearing Age Women in Manshera –NWFP, Pakistan (2006) World Food Program.
17. Tumor suppressor candidate 3 (TUSC3) prevents the epithelial-to mesenchymal transition and inhibits tumor growth by modulating the endoplasmic reticulum stress response in ovarian cancer cells. Kratochvílová K, Horak P, Ešner M, Souček K, Pils D, Anees M, Tomasich E, Dráfi F, Jurtíková V, Hampl A, Krainer M, and Vaňhara P - Under review (International Journal of Cancer).
18. The erratic antibiotic susceptibility patterns of Escherichia coli and Klebsiella pneumoniae isolates causing urinary tract infections. Ahmed I, Sajed M, Sultan A, Murtaza I, Yousaf S, Maqsood B, Vanhara P, Anees M – Under Review (New Microbiologica).
19. The dynamics of HIV/AIDS testing and screening strategies in Pakistan. Waheed U, Zaheer HA, Anees M – Under review (International Journal of Epidemiology).
Conferences Papers/Abstracts
20. Syphilis and HIV/AIDS among High Risk Groups: A Cross-Sectional Study from Rawalpindi, Pakistan. Raza H, Waheed U, Anees M. 5th Annual Public Health Conference, Health Services Academy, Islamabad, Pakistan. December 11-12, 2014.
21. National Food Safety Scenario and Strategies for Improvement. Anis RA, Aurangzeb, Anjum F, Anees M. International Congress, University of Agriculture Faisalabad, Pakistan. October 14-16, 2013.
22. Anomalies of TRAIL Pathway in MALT Lymphoma. Anees M, Horak P, Schiefer AI, Perco P, Müllauer L, Streubel B, Raderer M, Krainer M. International Conference on the Applications of Molecular Biology in Medicine and Agriculture, Islamabad, Pakistan, August 20-22, 2013, abstract # 61.
23. Loss of death receptor 5 expression in plasmacytic MALT Lymphoma is a common event and is associated with genetic aberrations. Anees M, Horak P, Müllauer L, Streubel B, Raderer M, Krainer M. 102nd Annual meeting of the AACR, Orlando, Florida, USA, April 2–6, 2011, abstract # 4777.
24. Genetic anomalies in MALT Lymphoma are associated with the loss of death receptor5
Anees M, Horak P, Müllauer L, Streubel B, Raderer M, Krainer M. 7th YSA PhD Symposium, Medical University of Vienna, Vienna, Austria, June 15–16, 2011, abstract # P06.
25. The impact of tumor-infiltrating natural killer cells on ovarian cancer progression
El-gazzar A, Eckelhart E, Perco P, Anees M, Horvat R, Sexl V, Krainer M. 102nd Annual meeting of the AACR, Orlando, Florida, USA, April 2–6, 2011, abstract # 3661.
26. ‘TRAIL’ to Tumor Immune Surveillance. Anees M. International workshop on Advances in Molecular and Cancer Biology, Brno, Czech Republic, November 11-12, 2010, abstract # 01.
27. TRAIL in tumor microenvironment influences prostate cancer survival. Anees M, Horak P, El-GazzarA, Pangerl T, Susani M, Oh W, Krainer M. 5th PhD Symposium, Medical University of Vienna, Vienna, Austria, June 17–19, 2009, abstract # P04.
28. Characterization of the TRAIL pathway in a syngenic mouse model of ovarian cancer
El-gazzar A, Anees M, Horvat R, Mayer B, Krainer M. 100th Annual meeting of the AACR, Denver, Colorado, USA, April 18–22, 2009, abstract # 5128.
29. Combination of DR5 agonistic antibody and chemotherapy eliminates ovarian cancer in mice. El-Gazzar A, Perco P, Eckelhart E, Anees M, Sexl V, Mayer B, Mikulits W, Krainer M. 5th PhD Symposium, Medical University of Vienna, Vienna, Austria, June 17–19, 2009, abstract P20.
30. Evidence that evolutionary conserved RF amide neuropeptides stimulate prolactin secretion in the adult male rhesus monkey (Macacamulatta). Salahuddin H, Wahab F, Anees M, Leprince J, Vaudry H, Tena-Sempere M, Shahab M. 1st South Asian Conference of Physiological Societies & 11th Biennial Conference of Pakistan Physiological Society on “Physiology Updates – Trends, Opportunities & Challenges”, Islamabad, Pakistan, November 10-12, 2008.
31. Kisspeptin does not directly stimulate testosterone secretion in the male rhesus monkey
Irfan S, Anees M, Zaman W, Shahab M. International Symposium on Endocrinology and Reproductive Sciences, Lahore University of Health Sciences, Lahore, Pakistan, February 13-14, 2007.
Research Interests
· Interaction of signal transduction pathways and consequent effect on cancer pathogenesis.
· TNF-Related Apoptosis-Inducing Ligand (TRAIL) pathway.
· Testing of drugs/plant extracts for their anti-cancer activity in vitro and in vivo.
· Cancer Immune Surveillance with reference to the involvement/contribution of specific immune cells.
Teaching Interests
· Biochemistry
· Molecular Biology
· Human physiology
· Targeted Molecular therapeutics (Advanced)
· Molecular Medicine (Advanced)
· Molecular Signal Transduction (Advanced)
· Cancer Research (Advanced)
Memberships
· Associate Member of the American Association of Cancer Research (AACR).
· Member of the International Neuroendocrine Federation (INF)
M.Phil. Theses Supervised
1. In vitro Study of Hirudin its Apoptosis Inducing Potential in Leishmaniasis Therapy (2013)
2. To Elucidate the Expression of DR5 in MALT Lymphoma (2013)
3. Synthesis and Characterization of Gold Nanoparticles with self assembled Ferrocene thiophenol as Biological Probe (2013)
4. Diversity in Antimicrobial Susceptibility Patterns of Klebsiella species causing Urinary Tract Infection (2014)
5. To Elucidate MALT Lymphoma Pathogenesis with reference to DR4 Expression (2014)
6. Current Antimicrobial Susceptibility Patterns of Escherichia coli species causing Urinary Tract Infection (2014)
7. Involvement of Flice-Like Inhibitory Protein in the Pathogenesis of MALT Lymphoma (2014)
Ph.D. Supervision
1. Molecular Characterization of HIV-1 Strains in Pakistani Population (On-going)
2. Identification and Molecular Characterization of Rare and Novel Genes Involved in Mental Retardation (On-going)
References
Available upon request.