Laura R Sadofsky Bibliography 2017

Atkinson, S. K., Sadofsky, L. R. & Morice, A. H. (2016) How does rhinovirus cause the common cold cough? BMJ Open Respir Res, 3(1), e000118.

Birrell, M. A., Belvisi, M. G., Grace, M., Sadofsky, L., Faruqi, S., Hele, D. J., Maher, S. A., Freund-Michel, V. & Morice, A. H. (2009) TRPA1 agonists evoke coughing in guinea pig and human volunteers. Am J RespirCrit Care Med, 180(11), 1042-7.

Botham, A., Guo, X., Xiao, Y. P., Morice, A. H., Compton, S. J. & Sadofsky, L. R. (2011) Palmitoylation of human proteinase-activated receptor-2 differentially regulates receptor-triggered ERK1/2 activation, calcium signalling and endocytosis. Biochem J, 438(2), 359-67.

De Logu, F., Tonello, R., Materazzi, S., Nassini, R., Fusi, C., Coppi, E., Li Puma, S., Marone, I. M., Sadofsky, L. R., Morice, A. H., Susini, T., Terreni, A., Moneti, G., Di Tommaso, M., Geppetti, P. & Benemei, S. (2016) TRPA1 Mediates Aromatase Inhibitor-Evoked Pain by the Aromatase Substrate Androstenedione. Cancer Res, 76(23), 7024-7035.

Fraser, S. D., Sadofsky, L. R., Kaye, P. M. & Hart, S. P. (2016) Reduced expression of monocyte CD200R is associated with enhanced proinflammatory cytokine production in sarcoidosis. Sci Rep, 6, 38689.

Hayman, Y., Sadofsky, LR., Williamson, JD., Hart, SP. and Morice, AH. (2017) The effects of exogenous lipid on THP-1 cells: An in vitro model of airway aspiration? European Respiratory Journal Open Research, In Press.

Mitchell, J. E., Campbell, A. P., New, N. E., Sadofsky, L. R., Kastelik, J. A., Mulrennan, S. A., Compton, S. J. & Morice, A. H. (2005) Expression and characterization of the intracellular vanilloid receptor (TRPV1) in bronchi from patients with chronic cough. Exp Lung Res, 31(3), 295-306.

Morgan, K., Sadofsky, L. R., Crow, C. & Morice, A. H. (2014) Human TRPM8 and TRPA1 pain channels, including a gene variant with increased sensitivity to agonists (TRPA1 R797T), exhibit differential regulation by SRC-tyrosine kinase inhibitor. Biosci Rep, 34(4).

Morgan, K., Sadofsky, L. R. & Morice, A. H. (2015) Genetic variants affecting human TRPA1 or TRPM8 structure can be classified in vitro as 'well expressed', 'poorly expressed' or 'salvageable'. Biosci Rep, 35(5).

Nassini, R., Materazzi, S., Andre, E., Sartiani, L., Aldini, G., Trevisani, M., Carnini, C., Massi, D., Pedretti, P., Carini, M., Cerbai, E., Preti, D., Villetti, G., Civelli, M., Trevisan, G., Azzari, C., Stokesberry, S., Sadofsky, L., McGarvey, L., Patacchini, R. & Geppetti, P. (2010) Acetaminophen, via its reactive metabolite N-acetyl-p-benzo-quinoneimine and transient receptor potential ankyrin-1 stimulation, causes neurogenic inflammation in the airways and other tissues in rodents. FASEB J, 24(12), 4904-16.

Nassini, R., Materazzi, S., Vriens, J., Prenen, J., Benemei, S., De Siena, G., la Marca, G., Andre, E., Preti, D., Avonto, C., Sadofsky, L., Di Marzo, V., De Petrocellis, L., Dussor, G., Porreca, F., Taglialatela-Scafati, O., Appendino, G., Nilius, B. & Geppetti, P. (2012) The 'headache tree' via umbellulone and TRPA1 activates the trigeminovascular system. Brain, 135(Pt 2), 376-90.

Ramachandran, R., Sadofsky, L. R., Xiao, Y., Botham, A., Cowen, M., Morice, A. H. & Compton, S. J. (2007) Inflammatory mediators modulate thrombin and cathepsin-G signaling in human bronchial fibroblasts by inducing expression of proteinase-activated receptor-4. Am J Physiol Lung Cell MolPhysiol, 292(3), L788-98.

Sadofsky, L. R., Boa, A. N., Maher, S. A., Birrell, M. A., Belvisi, M. G. & Morice, A. H. (2011) TRPA1 is activated by direct addition of cysteine residues to the N-hydroxysuccinyl esters of acrylic and cinnamic acids. Pharmacol Res, 63(1), 30-6.

Sadofsky, L. R., Campi, B., Trevisani, M., Compton, S. J. & Morice, A. H. (2008) Transient receptor potential vanilloid-1-mediated calcium responses are inhibited by the alkylamine antihistamines dexbrompheniramine and chlorpheniramine. Exp Lung Res, 34(10), 681-93.

Sadofsky, L. R., Cantero-Recasens, G., Wright, C., Valverde, M. A. & Morice, A. H. (2017a) TRPV1 polymorphisms influence capsaicin cough sensitivity in men. J Thorac Dis, 9(3), 839-840.

Sadofsky, L. R., Hayman, Y. A., Hart, S. P. & Morice, A. H. (2017b) Lipid Laden Macrophages in Respiratory Disease. J NeurogastroenterolMotil, 23(3), 477-478.

Sadofsky, L. R., Ramachandran, R., Crow, C., Cowen, M., Compton, S. J. & Morice, A. H. (2012) Inflammatory stimuli up-regulate transient receptor potential vanilloid-1 expression in human bronchial fibroblasts. Exp Lung Res, 38(2), 75-81.

Sadofsky, L. R., Ramachandran, R., Crow, C., Cowan, M., Compton, S.J. and Morice, A.H. (2012) Inflammatory stimuli upregulate TRPV1 expression in human bronchial fibroblasts. Experimental Lung Research.

Sadofsky, L. R., Sreekrishna, K. T., Lin, Y., Schinaman, R., Gorka, K., Mantri, Y., Haught, J. C., Huggins, T. G., Isfort, R. J., Bascom, C. C. & Morice, A. H. (2014) Unique Responses are Observed in Transient Receptor Potential Ankyrin 1 and Vanilloid 1 (TRPA1 and TRPV1) Co-Expressing Cells. Cells, 3(2), 616-26.

Vancauwenberghe, E., Noyer, L., Derouiche, S., Lemonnier, L., Gosset, P., Sadofsky, L. R., Mariot, P., Warnier, M., Bokhobza, A., Slomianny, C., Mauroy, B., Bonnal, J. L., Dewailly, E., Delcourt, P., Allart, L., Desruelles, E., Prevarskaya, N. & Roudbaraki, M. (2017) Activation of mutated TRPA1 ion channel by resveratrol in human prostate cancer associated fibroblasts (CAF). MolCarcinog, 56(8), 1851-1867.

Williamson, J. D., Sadofsky, L. R., Crooks, M. G., Greenman, J. & Hart, S. P. (2016) Bleomycin increases neutrophil adhesion to human vascular endothelial cells independently of upregulation of ICAM-1 and E-selectin. Exp Lung Res, 42(8-10), 397-407.

Williamson, J. D., Sadofsky, L. R. & Hart, S. P. (2015) The pathogenesis of bleomycin-induced lung injury in animals and its applicability to human idiopathic pulmonary fibrosis. Exp Lung Res, 41(2), 57-73.

Xiao, Y. P., Morice, A. H., Compton, S. J. & Sadofsky, L. (2011) N-linked glycosylation regulates human proteinase-activated receptor-1 cell surface expression and disarming via neutrophil proteinases and thermolysin. J BiolChem, 286(26), 22991-3002.