Table S1. S. aureus genes up-regulated in response to growth in 2 M NaCl.Gray shading indicates genes that were induced by ten-fold or more (or predicted operons for which at least one ORF in the operon meets this criterion). A locus number in boldface font indicates loci that may be involved in the intracellular accumulation of amino acids or chemically related compatible solutes.
Fold Up-regulated NaCl / Locus / Gene / Description / COG/ Description / Transcriptional unitProbe sequence present in COL genome:
2.7 / SACOL0008 / hutH / histidine ammonia-lyase / Amino acid transport and metabolism
3.6 / SACOL0073 / conserved hypothetical protein
2.1 / SACOL0080/SACOL0081 / Intergenic region between SACOL0080 and SACOL0081 / Intergenic region
4.3 / SACOL0100 / sbnA / O-acetyl serine sulfhydrylase / Amino acid transport and metabolism / sbnA-sbnB-sbnC-sbnD-sbnE-sbnF
4.6 / SACOL0101 / sbnB / ornithine cyclodeaminase / Amino acid transport and metabolism / sbnA-sbnB-sbnC-sbnD-sbnE-sbnF
4.4 / SACOL0102 / sbnC / siderophore biosynthesis IucC family protein / sbnA-sbnB-sbnC-sbnD-sbnE-sbnF
2.5 / SACOL0103 / sbnD / membrane transporter protein / Transport / sbnA-sbnB-sbnC-sbnD-sbnE-sbnF
2.3 / SACOL0104 / sbnE / siderophore biosynthesis IucA family protein / sbnA-sbnB-sbnC-sbnD-sbnE-sbnF
2.3 / SACOL0105 / sbnF / siderophore biosynthesis IucC family protein / sbnA-sbnB-sbnC-sbnD-sbnE-sbnF
37.8 / SACOL0136 / cap5A / capsular polysaccharide biosynthesis protein Cap5A (cap5A) / Cell wall/membrane biogenesis / cap5ABCDEFGHIJKLMNO
46.1 / SACOL0137 / cap5B / capsular polysaccharide biosynthesis protein Cap5B (cap5B) / Cell wall/membrane biogenesis / cap5ABCDEFGHIJKLMNO
25.9 / SACOL0138 / cap5C / capsular polysaccharide biosynthesis protein Cap5C (cap5C) / Cell wall/membrane biogenesis / cap5ABCDEFGHIJKLMNO
11.6 / SACOL0139 / cap5D / capsular polysaccharide biosynthesis protein Cap5D (cap5D) / Cell wall/membrane biogenesis / cap5ABCDEFGHIJKLMNO
7.7 / SACOL0140 / cap5E / capsular polysaccharide biosynthesis protein Cap5E (cap5E) / Cell wall/membrane biogenesis / cap5ABCDEFGHIJKLMNO
8.9 / SACOL0141 / cap5F / capsular polysaccharide biosynthesis protein Cap5F (cap5F) / Cell wall/membrane biogenesis / cap5ABCDEFGHIJKLMNO
11.1 / SACOL0142 / cap5G / UDP-N-acetylglucosamine 2-epimerase Cap5G (cap5G) / Cell wall/membrane biogenesis / cap5ABCDEFGHIJKLMNO
7.0 / SACOL0143 / cap5H / capsular polysaccharide biosynthesis protein Cap5H (cap5H) / Cell wall/membrane biogenesis / cap5ABCDEFGHIJKLMNO
4.6 / SACOL0144 / cap5I / capsular polysaccharide biosynthesis protein Cap5I (cap5I) / Cell wall/membrane biogenesis / cap5ABCDEFGHIJKLMNO
3.7 / SACOL0145 / cap5J / capsular polysaccharide biosynthesis protein Cap5J (cap5J) / Cell wall/membrane biogenesis / cap5ABCDEFGHIJKLMNO
2.7 / SACOL0146 / cap5K / capsular polysaccharide biosynthesis protein Cap5K (cap5K) / Cell wall/membrane biogenesis / cap5ABCDEFGHIJKLMNO
3.0 / SACOL0147 / cap5L / capsular polysaccharide biosynthesis protein Cap5L (cap5L) / Cell wall/membrane biogenesis / cap5ABCDEFGHIJKLMNO
3.8 / SACOL0148 / cap5M / capsular polysaccharide biosynthesis galactosyltransferase Cap5M (cap5M) / Cell wall/membrane biogenesis / cap5ABCDEFGHIJKLMNO
3.3 / SACOL0149 / cap5N / capsular polysaccharide biosynthesis protein Cap5N (cap5N) / Cell wall/membrane biogenesis / cap5ABCDEFGHIJKLMNO
3.7 / SACOL0150 / cap5O / capsular polysaccharide biosynthesis protein Cap5O (cap5O) / Cell wall/membrane biogenesis / cap5ABCDEFGHIJKLMNO
9.9 / SACOL0154 / aldA1 / aldehyde dehydrogenase (aldA1) / Energy production and conversion
5.1 / SACOL0156 / hypothetical protein
3.1/2.8 / SACOL0163/SACOL0164 / Intergenic region between SACOL0163 and SACOL0164 / Intergenic region
3.0/3.3 / SACOL0164 / gramicidin S synthetase 2 related protein / Secondary metabolite biosynthesis, transport and catabolism / SACOL0164-SACOL0165
2.7 / SACOL0173 / ipdC / indole-3-pyruvate decarboxylase (ipdC) / Amino acid transport and metabolism
10.0 / SACOL0176 / conserved hypothetical protein / SACOL0176-murQ-SACOL0178-SACOL0179
7.5 / SACOL0177 / murQ / N-acetylmuramic acid-6-phosphate etherase / SACOL0176-murQ-SACOL0178-SACOL0179
3.4/2.9 / SACOL0178 / PTS system, IIBC components / SACOL0176-murQ-SACOL0178-SACOL0179
3.0 / SACOL0179 / RpiR family phosphosugar-binding transcriptional regulator / Transcription / SACOL0176-murQ-SACOL0178-SACOL0179
2.2 / SACOL0188 / ggt / gamma-glutamyltranspeptidase (ggt) / SACOL0185-SACOL0186-SACOL0187-ggt
3.3 / SACOL0200 / uhpT / sugar phosphate antiporter / Carbohydrate transport and metabolism
2.1 / SACOL0215 / propionate CoA-transferase / Lipid transport and metabolism / SACOL0215-SACOL0214-SACOL0213
2.0 / SACOL0232 / PTS system, sorbitol-specific IIC component / Carbohydrate transport and metabolism / SACOL0232-gutB-SACOL0234-SACOL0235
2.9 / SACOL0239 / teichoic acid biosynthesis protein F / Cell wall/membrane biogenesis
3.2 / SACOL0253 / rbsK / ribokinase (rbsK) / Carbohydrate transport and metabolism / SACOL0255-SACOL0254-rbsK
5.4 / SACOL0254 / rbsD / D-ribose pyranase / Carbohydrate transport and metabolism / SACOL0255-SACOL0254-rbsK
4.1 / SACOL0255 / rbsU / ribose transporter (rbsU) / Carbohydrate transport and metabolism / SACOL0255-SACOL0254-rbsK
2.7 / SACOL0262 / choloylglycine hydrolase family protein / Cell wall/membrane biogenesis
2.0 / SACOL0262/SACOL0263 / Intergenic region between SACOL0262 and lytM / Intergenic region
3.4 / SACOL0308 / carbohydrate kinase, PfkB family / Carbohydrate transport and metabolism
13.7 / SACOL0311 / (nanT) / Na+:solute symporter family protein / Transport / nanA-(nanT)
7.1 / SACOL0312 / nanA / N-acetylneuraminatelyase (nanA) / nanA-(nanT)
7.6 / SACOL0313 / ROK family protein
5.5 / SACOL0313/SACOL0314 / Intergenic region between SACOL0313 and SACOL0314 / Intergenic region
3.6 / SACOL0317 / lipase precursor, interruption-N/triacylglycerol lipase/glycerol ester hydrolase
2.0 / SACOL0375 / prophage L54a, major tail protein / SACOL0371-SACOL0372-SACOL0373-SACOL0374-SACOL0375
2.1 / SACOL0376 / prophage L54a, major tail protein / Cell motility
2.4 / SACOL0382 / hypothetical protein / SACOL0378-SACOL0379-SACOL0380-SACOL0381-SACOL0382-SACOL0383-SACOL0384-SACOL0385-SACOL0386
4.6 / SACOL0392 / Oye family NADH-dependent flavinoxidoreductase / Energy production and conversion
3.0 / SACOL0393/SACOL0394 / Intergenic region between SACOL0393 and SACOL0394 / Intergenic region
2.9 / SACOL0394 / conserved hypothetical protein / Energy production and conversion
6.1 / SACOL0400 / ulaA / PTS system, IIC component / Carbohydrate transport and metabolism / SACOL0403-SACOL0402-SACOL0401-ulaA
10.2 / SACOL0401 / PTS system, IIB component / Carbohydrate transport and metabolism / SACOL0403-SACOL0402-SACOL0401-ulaA
9.3 / SACOL0402 / PTS system, IIA component / Carbohydrate transport and metabolism / SACOL0403-SACOL0402-SACOL0401-ulaA
7.4 / SACOL0403 / BglG family transcriptional antiterminator / Transcription / SACOL0403-SACOL0402-SACOL0401-ulaA
2.1 / SACOL0407 / glpT / glycerol-3-phosphate transporter (glpT) / Carbohydrate transport and metabolism
2.2 / SACOL0408 / glyoxalase family protein
2.3 / SACOL0413 / ribosomal-protein-serine acetyltransferase, putative / Translation
5.0 / SACOL0414 / putative lipoprotein / Inorganic ion transport and metabolism / SACOL0414-SACOL0415-SACOL0416
5.7/7.9 / SACOL0415 / Dyp-type peroxidase family protein / Inorganic ion transport and metabolism / SACOL0414-SACOL0415-SACOL0416
2.7 / SACOL0416 / iron permease FTR1 family protein / Inorganic ion transport and metabolism / SACOL0414-SACOL0415-SACOL0416
2.3 / SACOL0431/SACOL0432 / Intergenic region between SACOL0431 and SACOL0432 / Intergenic region
2.7 / SACOL0467 / FAD/NAD(P)-binding Rossmann fold superfamily protein / SACOL0467-SACOL0466
3.2 / SACOL0491/SACOL0494 / Intergenic region between SACOL0491 and nuoF / Intergenic region
2.5 / SACOL0517 / alpha, alpha-phosphotrehalase / SACOL0517-SACOL0518
2.7 / SACOL0598 / araB / ribulokinase / Energy production and conversion
2.3 / SACOL0599 / NAD-dependent epimerase/dehydratase family protein / Amino acid transport and metabolism
2.0 / SACOL0600 / ilvE / branched-chain amino acid aminotransferase (ilvE) / Amino acid transport and metabolism
4.1 / SACOL0608 / sdrC / Ser-Asp rich fibrinogen-binding, bone sialoprotein-binding protein SdrC
3.8 / SACOL0655 / aldo/keto reductase family oxidoreductase / Energy production and conversion
3.1 / SACOL0655/SACOL0656 / Intergenic region between SACOL0655 and SACOL0656 / Intergenic region
5.8 / SACOL0707 / dihydroxyacetone kinase subunit DhaK / Carbohydrate transport and metabolism
3.5 / SACOL0708 / dihydroxyacetone kinase subunit DhaL / Carbohydrate transport and metabolism
2.1 / SACOL0807 / conserved hypothetical protein / SACOL0808-SACOL0807-pepT
2.2 / SACOL0808 / membrane protein, putative
2.8 / SACOL0824 / uvrA / excinuclease ABC subunit A / uvrB-uvrA
2.2 / SACOL0825 / hprK / HPr kinase/phosphatase (hprK) / Signal transduction / hprK-lgt-SACOL0827-SACOL0828
2.3 / SACOL0854/SACOL0855 / Intergenic region between SACOL0854 and SACOL0855 / Intergenic region
2.9 / SACOL0870 / LysE/YggA family protein
4.0 / SACOL0872 / OsmC/Ohr family protein / Posttranslational modification, protein turnover, chaperone
2.0 / SACOL0873 / aroD / 3-dehydroquinate dehydratase, type I (aroD)
2.5 / SACOL0880 / Toprim domain protein / Replication, recombination and repair / SACOL0880-SACOL0881
2.4 / SACOL0881 / thioredoxin, putative
2.2 / SACOL0928/SACOL0929 / Intergenic region between SACOL0928 and SACOL0929 / Intergenic region
2.7 / SACOL0959 / Oye family NADH-dependent flavinoxidoreductase / Energy production and conversion
14.4 / SACOL0960 / rocD / ornithine aminotransferase (rocD) / Amino acid transport and metabolism
18.4 / SACOL0960/SACOL0961 / intergenic region between rocD and gluD / Intergenic region
4.3 / SACOL0961 / gluD / glutamate dehydrogenase, NAD-specific (gluD) / Amino acid transport and metabolism
4.4 / SACOL0962 / glycerophosphoryldiesterphosphodiesteraseGlpQ / Energy production and conversion
3.0 / SACOL0964 / argG / argininosuccinate synthase (argG) / Amino acid transport and metabolism / argG-argH
2.4 / SACOL0985 / surface protein
2.3 / SACOL1073 / purE / phosphoribosylaminoimidazole carboxylase, catalytic subunit (purE) / Nucleotide transport and metabolism / purE-purK-purC-purS-purQ-purL-purF-purM-purN-purH-purD
2.4 / SACOL1074 / purK / phosphoribosylaminoimidazole carboxylase, ATPase subunit (purK) / Nucleotide transport and metabolism / purE-purK-purC-purS-purQ-purL-purF-purM-purN-purH-purD
4.1 / SACOL1077 / purQ / phosphoribosylformylglycinamidine synthase I (purQ) / Nucleotide transport and metabolism / purE-purK-purC-purS-purQ-purL-purF-purM-purN-purH-purD
4.2 / SACOL1078 / purL / phosphoribosylformylglycinamidine synthase II (purL) / Nucleotide transport and metabolism / purE-purK-purC-purS-purQ-purL-purF-purM-purN-purH-purD
2.8 / SACOL1079 / purF / amidophosphoribosyltransferase (purF) / Nucleotide transport and metabolism / purE-purK-purC-purS-purQ-purL-purF-purM-purN-purH-purD
2.4 / SACOL1080 / purM / phosphoribosylformylglycinamidinecyclo-ligase (purM) / Nucleotide transport and metabolism / purE-purK-purC-purS-purQ-purL-purF-purM-purN-purH-purD
2.5 / SACOL1081 / purN / phosphoribosylglycinamideformyltransferase (purN) / Nucleotide transport and metabolism / purE-purK-purC-purS-purQ-purL-purF-purM-purN-purH-purD
2.5 / SACOL1082 / purH / bifunctionalphosphoribosylaminoimidazolecarboxamideformyltransferase/IMP cyclohydrolase / Nucleotide transport and metabolism / purE-purK-purC-purS-purQ-purL-purF-purM-purN-purH-purD
2.0 / SACOL1106 / conserved hypothetical protein
2.2 / SACOL1123 / pyc / pyruvate carboxylase (pyc) / Energy production and conversion
2.5 / SACOL1158 / sdhC / succinate dehydrogenase, cytochrome b558 subunit (sdhC) / Energy production and conversion
3.9 / SACOL1158/SACOL1159 / Intergenic region between sdhC and sdhA / Intergenic region
3.6 / SACOL1159 / sdhA / succinate dehydrogenase, flavoprotein subunit (sdhA) / Energy production and conversion / sdhA-sdhB
2.5 / SACOL1160 / sdhB / succinate dehydrogenase, iron-sulfur protein (sdhB) / Energy production and conversion / sdhA-sdhB
5.9 / SACOL1186 / antibacterial protein (phenol soluble modulin)
13.7 / SACOL1186/SACOL1187 / intergenic region between SACOL1186/SACOL1187 / Intergenic region
5.8 / SACOL1187 / antibacterial protein (phenol soluble modulin)
2.2 / SACOL1262 / sucC / succinyl-CoA synthase, beta subunit (sucC) / Energy production and conversion / sucC-sucD
3.2 / SACOL1263 / sucD / succinyl-CoA synthase, alpha subunit (sucD) / Energy production and conversion / sucC-sucD
2.5 / SACOL1264 / lytN / cell wall hydrolase (lytN) / lytN-eprH
2.5 / SACOL1269 / xerC / tyrosine recombinaseXerC / Replication, recombination and repair / xerC-hslV
2.1 / SACOL1308 / pyruvate ferredoxinoxidoreductase, alpha subunit / Energy production and conversion / SACOL1308-SACOL1309
2.5 / SACOL1359 / conserved hypothetical protein
3.3 / SACOL1359/SACOL1360 / Intergenic region between SACOL1359 and SACOL1360 / Intergenic region
2.0 / SACOL1362 / hom / homoserine dehydrogenase (hom) / Amino acid transport and metabolism / hom-thrC-thrB
3.3 / SACOL1415 / peptide ABC transporter, ATP-binding protein / Transport / SACOL1417-SACOL1416-SACOL1415-SACOL1414
2.8 / SACOL1416 / peptide ABC transporter, permease protein / Transport / SACOL1417-SACOL1416-SACOL1415-SACOL1414
3.2 / SACOL1417 / peptide ABC transporter, permease protein / Transport / SACOL1417-SACOL1416-SACOL1415-SACOL1414
7.1 / SACOL1428 / lysC / aspartokinase, alpha and beta subunits (lysC) / Amino acid transport and metabolism / lysC-asd-dapA-dapB-dapD
3.5 / SACOL1429 / asd / aspartate-semialdehyde dehydrogenase (asd) / Amino acid transport and metabolism / lysC-asd-dapA-dapB-dapD
2.8 / SACOL1430 / dapA / dihydrodipicolinate synthase (dapA) / Amino acid transport and metabolism / lysC-asd-dapA-dapB-dapD
3.6 / SACOL1431 / dapB / dihydrodipicolinate reductase (dapB) / Amino acid transport and metabolism / lysC-asd-dapA-dapB-dapD
3.0 / SACOL1432 / dapD / 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase (dapD) / Amino acid transport and metabolism / lysC-asd-dapA-dapB-dapD
3.4 / SACOL1448 / sucB / 2-oxoglutarate dehydrogenase, E2 component, dihydroipoamidesuccinyltransferase (sucB) / Energy production and conversion / sucA-sucB
5.0 / SACOL1449 / sucA / 2-oxoglutarate dehydrogenase, E1 component (sucA) / Energy production and conversion / sucA-sucB
2.5 / SACOL1508 / SACOL1507-SACOL1508
2.8 / SACOL1523 / recQ2 / ATP-dependent DNA helicase RecQ (recQ2) / Replication, recombination and repair / SACOL1524-recQ2
2.2 / SACOL1532 / hypothetical protein / Cell cycle control, mitosis and meiosis / SACOL1533-SACOL1532
2.5 / SACOL1543 / aldo/keto reductase family oxidoreductase / Energy production and conversion
3.4 / SACOL1551 / malA / alpha-glucosidase (malA) / malR-malA
4.3 / SACOL1552 / malR / maltose operon repressor (malR) / Transcription / malR-malA
2.4 / SACOL1583/SACOL1584 / Intergenic region between SACOL1583 and SACOL1584
2.1 / SACOL1585/SACOL1586 / Intergenic region between SACOL1585 and SACOL1586 / Intergenic region
2.4 / SACOL1593 / glycine cleavage system P protein, subunit 2 / Amino acid transport and metabolism / gcvT-SACOL1594-SACOL1593
2.5 / SACOL1594 / glycine cleavage system P protein, subunit 1 / Amino acid transport and metabolism / gcvT-SACOL1594-SACOL1593
3.3 / SACOL1595 / gcvT / glycine cleavage system T protein (gcvT) / Amino acid transport and metabolism / gcvT-SACOL1594-SACOL1593
3.2 / SACOL1607/SACOL1608 / Intergenic region between SACOL1607 and rpmG / Intergenic region
3.4 / SACOL1659 / conserved hypothetical protein / Inorganic ion transport and metabolism / SACOL1664-SACOL1663-SACOL1662-SACOL1661-SACOL1660-SACOL1659
2.7 / SACOL1660 / LamB/YcsF family protein / SACOL1664-SACOL1663-SACOL1662-SACOL1661-SACOL1660-SACOL1659
3.9 / SACOL1661 / acetyl-CoA carboxylase, biotin carboxylase / Lipid transport and metabolism / SACOL1664-SACOL1663-SACOL1662-SACOL1661-SACOL1660-SACOL1659
3.6 / SACOL1662 / acetyl-CoA carboxylase, biotin carboxyl carrier protein / Lipid transport and metabolism / SACOL1664-SACOL1663-SACOL1662-SACOL1661-SACOL1660-SACOL1659
4.9 / SACOL1663 / urea amidolyase-related protein / SACOL1664-SACOL1663-SACOL1662-SACOL1661-SACOL1660-SACOL1659
4.9 / SACOL1664 / conserved hypothetical protein / SACOL1664-SACOL1663-SACOL1662-SACOL1661-SACOL1660-SACOL1659
2.5 / SACOL1724 / MutT/nudix family protein / SACOL1724-SACOL1723
5.8 / SACOL1734 / gapA2 / glyceraldehyde 3-phosphate dehydrogenase (gapA2) / Carbohydrate transport and metabolism
2.6 / SACOL1740/SACOL1741 / Intergenic region between phoP and icd / Intergenic region
3.4 / SACOL1742 / gltA / citrate synthase (gltA) / Energy production and conversion / gltA-icd
2.3 / SACOL1757/SACOL1758 / Intergenic region between SACOL1757 and ald2 / Intergenic region
5.5 / SACOL1758 / ald2 / alanine dehydrogenase (ald2) / Amino acid transport and metabolism
3.4 / SACOL1770 / glycerophosphoryldiesterphosphodiesterase / Energy production and conversion
2.4 / SACOL1782 / fhs / formate--tetrahydrofolate ligase (fhs) / Nucleotide transport and metabolism
2.7 / SACOL1784 / acuA / acetoin utilization protein AcuA (acuA) / acuA-acuC
2.6 / SACOL1785 / acuC / acetoin utilization protein AcuC (acuC) / acuA-acuC
2.5 / SACOL1806 / cell wall surface anchor family protein / Replication, recombination and repair
9.9 / SACOL1816 / putA / proline dehydrogenase (putA) / Amino acid transport and metabolism
2.0 / SACOL1818 / ribBA / 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II (ribBA) / Coenzyme transport and metabolism / ribD-ribE-ribBA-ribH
2.3 / SACOL1820 / ribD / riboflavin biosynthesis protein RibD (ribD) / Coenzyme transport and metabolism / ribD-ribE-ribBA-ribH
12.7 / SACOL1838 / pckA / phosphoenolpyruvate carboxykinase (ATP) (pckA) / Energy production and conversion
2.2 / SACOL1844 / menE / O-succinylbenzoic acid-CoA ligase (menE)
2.0 / SACOL1854 / hypothetical protein / SACOL1854-SACOL1853
2.9 / SACOL1878/SACOL1879 / Intergenic region between epiA and SACOL1879 / Intergenic region
2.5 / SACOL1878/SACOL1879 / Intergenic region between epiA and SACOL1879 / Intergenic region
2.1 / SACOL1878/SACOL1879 / Intergenic region between epiA and SACOL1879 / Intergenic region
2.1 / SACOL1889 / hemE / uroporphyrinogen decarboxylase (hemE) / Coenzyme transport and metabolism / SACOL1890-hemE-hemH-hemG
2.1 / SACOL1890/SACOL1891 / Intergenic region between SACOL1890 and SACOL1891 / Intergenic region
2.6 / SACOL1908 / fumC / fumaratehydratase, class II (fumC) / Energy production and conversion
3.6 / SACOL1932/SACOL1933 / Intergenic region between SACOL1932 and SACOL1933 / Intergenic region
2.3 / SACOL1933/SACOL1934 / Intergenic region between SACOL1933 and SACOL1934 / Intergenic region
3.1 / SACOL1979 / Na+-dependent transporter / Inorganic ion transport and metabolism
2.7 / SACOL1979/SACOL1980 / Intergenic region between SACOL1979 and SACOL1980 / Intergenic region
2.8 / SACOL1999 / conserved hypothetical protein
3.9 / SACOL2021/SACOL2022 / Intergenic region between SACOL2021 and hld / Intergenic region
2.1 / SACOL2022 / hld / delta-hemolysin (hld)
2.3 / SACOL2033 / conserved hypothetical protein / Posttranslational modification, protein turnover, chaperone
2.6 / SACOL2034 / conserved hypothetical protein
3.4 / SACOL2042 / ilvD / dihydroxy-acid dehydratase (ilvD) / Amino acid transport and metabolism / ilvD-ilvB-SACOL2044-ilvC-leuA-leuB-leuC-leuD-ilvA2
2.2 / SACOL2043 / ilvB / acetolactate synthase, large subunit, biosynthetic type (ilvB) / Amino acid transport and metabolism / ilvD-ilvB-SACOL2044-ilvC-leuA-leuB-leuC-leuD-ilvA2
2.3 / SACOL2045 / ilvC / ketol-acid reductoisomerase (ilvC) / Amino acid transport and metabolism / ilvD-ilvB-SACOL2044-ilvC-leuA-leuB-leuC-leuD-ilvA2
2.3 / SACOL2046 / leuA / 2-isopropylmalate synthase (leuA) / Amino acid transport and metabolism / ilvD-ilvB-SACOL2044-ilvC-leuA-leuB-leuC-leuD-ilvA2
3.2 / SACOL2047 / leuB / 3-isopropylmalate dehydrogenase (leuB) / Amino acid transport and metabolism / ilvD-ilvB-SACOL2044-ilvC-leuA-leuB-leuC-leuD-ilvA2
2.3 / SACOL2048 / leuC / 3-isopropylmalate dehydratase, large subunit (leuC) / Amino acid transport and metabolism / ilvD-ilvB-SACOL2044-ilvC-leuA-leuB-leuC-leuD-ilvA2
2.2 / SACOL2049 / leuD / 3-isopropylmalate dehydratase, small subunit (leuD) / Amino acid transport and metabolism / ilvD-ilvB-SACOL2044-ilvC-leuA-leuB-leuC-leuD-ilvA2
35.1 / SACOL2066 / kdpC / K+-transporting ATPase, C subunit (kdpC) / Inorganic ion transport and metabolism / kdpFABC
37.8 / SACOL2067 / kdpB / K+-transporting P-type ATPase, B subunit (kdpB) / Inorganic ion transport and metabolism / kdpFABC
102.4 / SACOL2068 / kdpA / K+-transporting ATPase, A subunit (kdpA) / Inorganic ion transport and metabolism / kdpFABC
51.6 / SACOL2069 / kdpF / K+-transporting ATPase, F subunit (kdpF) / Inorganic ion transport and metabolism / kdpFABC
12.0 / SACOL2070 / kdpD / sensor histidine kinase KdpD (kdpD) / Signal transduction / kdpDE
8.7 / SACOL2071 / kdpE / DNA-binding response regulator KdpE (kdpE) / Signal transduction / kdpDE
21.4 / SACOL2088 / sceD / putative lytic transglycosylaseSceD (sceD)
2.7 / SACOL2154 / rocF / arginase (rocF) / Amino acid transport and metabolism
3.6 / SACOL2154/SACOL2155 / Intergenic region between rocF and SACOL2155 / Intergenic region
2.5 / SACOL2163 / conserved hypothetical protein
2.0 / SACOL2163/SACOL2164 / Intergenic region between SACOL2163 and SACOL2164 / Intergenic region
3.2 / SACOL2169 / aerobactin biosynthesis protein / SACOL2170-SACOL2169-SACOL2168
2.7 / SACOL2170 / transporter / Transport / SACOL2170-SACOL2169-SACOL2168
2.0 / SACOL2178 / alcohol dehydrogenase, zinc-containing / SACOL2178-SACOL2177
2.2 / SACOL2197 / surface protein
2.1 / SACOL2199 / budB / acetolactate synthase, catabolic (budB) / Amino acid transport and metabolism / budB-budA1
2.1 / SACOL2276 / inosine-uridine preferring nucleoside hydrolase / Nucleotide transport and metabolism
2.1 / SACOL2281 / ureB / urease subunit beta (ureB) / ureA-ureB-ureC-ureE-ureE-ureF-ureG-ureD
3.1 / SACOL2296 / glycerate dehydrogenase
2.2 / SACOL2313 / haloaciddehalogenase-like (HAD) family hydrolase / SACOL2313-SACOL2312
2.1 / SACOL2314 / Na+/bile acid symporter family protein / Transport
2.2 / SACOL2320 / conserved hypothetical protein
3.1 / SACOL2322 / M20/M25/M40 family peptidase
2.4 / SACOL2323 / hutI / imidazolonepropionase (hutI) / Amino acid transport and metabolism / hutU-hutI
5.3 / SACOL2324 / hutU / urocanatehydratase (hutU) / Amino acid transport and metabolism / hutU-hutI
2.0 / SACOL2325 / LysR family transcriptional regulator / Transcription
2.3 / SACOL2341 / fni / isopentenyl diphosphate isomerase (fni) / Energy production and conversion / SACOL2342-fni
2.1 / SACOL2365/SACOL2366 / Intergenic region between SACOL2365 and SACOL2366 / Intergenic region
2.1 / SACOL2367 / alcohol dehydrogenase, zinc-containing
2.1 / SACOL2369 / pyridine nucleotide-disulfide oxidoreductase / Posttranslational modification, protein turnover, chaperone
2.0 / SACOL2390 / sensory box histidine kinase / Signal transduction / narJ-narI-SACOL2391-SACOL2390-SACOL2389
2.1 / SACOL2391 / conserved hypothetical protein / Signal transduction / narJ-narI-SACOL2391-SACOL2390-SACOL2389
2.8 / SACOL2435 / glycerate kinase
10.2/
9.7 / SACOL2441 / amino acid permease / Amino acid transport and metabolism
2.1 / SACOL2483 / transporter / Coenzyme transport and metabolism
2.4 / SACOL2504 / permease / Transport
2.8 / SACOL2505 / cell wall surface anchor family protein
3.4 / SACOL2514/SACOL2515 / Intergenic region between gntP and gntK / Intergenic region
2.1 / SACOL2517 / MerR family transcriptional regulator / Transcription
2.2 / SACOL2517/SACOL2518 / Intergenic region between SACOL2517 and SACOL2518 / Intergenic region
2.6 / SACOL2518 / conserved hypothetical protein
2.2 / SACOL2527 / fbp / fructose-1,6-bisphosphatase, putative
2.3 / SACOL2528 / conserved hypothetical protein
8.4 / SACOL2544 / sdaAA / L-serine dehydratase, iron-sulfur-dependent, alpha subunit (sdaA) / Amino acid transport and metabolism / SACOL2546-sdaAB-sdaAA-SACOL2543
7.8 / SACOL2545 / sdaAB / L-serine dehydratase, iron-sulfur-dependent, beta subunit (sdaAB) / Amino acid transport and metabolism / SACOL2546-sdaAB-sdaAA-SACOL2543
9.4 / SACOL2546 / perfringolysin O regulator protein, putative / Carbohydrate transport and metabolism / SACOL2546-sdaAB-sdaAA-SACOL2543
2.1 / SACOL2549 / esterase, putative / Lipid transport and metabolism
5.1 / SACOL2568 / hypothetical protein
4.6 / SACOL2568/SACOL2569 / Intergenic region between SACOL2568 and SACOL2569 / Intergenic region
5.6 / SACOL2569 / rocA / delta-1-pyrroline-5-carboxylate dehydrogenase / Energy production and conversion
5.2/4.6 / SACOL2569/SACOL2570 / Intergenic region between SACOL2569 and SACOL2570 / Intergenic region
3.3 / SACOL2570 / galactoside O-acetyltransferase
3.4 / SACOL2574 / D-lactate dehydrogenase / SACOL2575-SACOL2574
5.3 / SACOL2575 / aminotransferase, class I / Amino acid transport and metabolism / SACOL2575-SACOL2574
6.0 / SACOL2575/SACOL2576 / Intergenic region between SACOL2575 and crtN
2.2 / SACOL2577 / crtM / dehydrosqualene synthase (crtM) / Carotenoid biosynthesis / crtO-crtP-crtQ-crtM-crtN
2.2 / SACOL2578 / crtQ / glycosyl transferase, group 2 family protein / Carotenoid biosynthesis / crtO-crtP-crtQ-crtM-crtN
2.6 / SACOL2579 / crtP / phytoene dehydrogenase / Carotenoid biosynthesis / crtO-crtP-crtQ-crtM-crtN
2.0 / SACOL2605 / conserved hypothetical protein
2.7 / SACOL2612 / CocE/NonD family hydrolase
2.5 / SACOL2628 / betB / betaine aldehyde dehydrogenase (betB) / Energy production and conversion / betB-betA
2.0 / SACOL2650/SACOL2651 / Intergenic region between SACOL2650 and SACOL2651 / Intergenic region
2.0 / SACOL2662/SACOL2663 / Intergenic region between SACOL2662 and SACOL2663 / Intergenic region
2.3 / SACOL2663 / PTS system, fructose-specific IIABC components / Carbohydrate transport and metabolism / SACOL2663-manA2
2.4 / SACOL2664 / manA2 / mannose-6-phosphate isomerase (manA2) / Carbohydrate transport and metabolism / SACOL2663-manA2
2.1 / SACOL2670 / glycosyl transferase, group 1 family protein / Cell wall/membrane biogenesis / SACOL2672-SACOL2671-SACOL2670-SACOL2669
2.5 / SACOL2682/SACOL2683 / Intergenic region between SACOL2682 and SACOL2683 / Intergenic region
3.1 / SACOL2692 / icaC / intercellular adhesion protein C
5.3/3.3 / SACOL2692/SACOL2693 / Intergenic region between icaC and SACOL2693
14.0 / SACOL2694 / geh / lipase / geh-SACOL2693
3.2 / SACOL2712 / drp35 / drP35 protein
2.8 / SACOL2722 / N-acetyltransferase family protein
Probe sequence present in USA300_FPR3757 genome:
2.2 / SAUSA300_1959 / conserved hypothetical protein
2.2 / SAUSA300_1960 / conserved hypothetical protein
2.3 / SAUSA300_1961/SAUSA300_1962 / Intergenic region between SAUSA300_1961 and SAUSA300_1962
2.2 / SAUSA300_1964 / conserved hypothetical protein
2.2 / SAUSA300_1967
2.1/2.1 / SAUSA300_1967/SAUSA300_1968 / Intergenic region between SAUSA300_1967 and SAUSA300_1968
Probe sequence present in Newman genome:
2.2/2.3/2.9 / NWMN_0268 / phage anti-repressor protein