Table S5. Interspecies homology ofFGB

Human / Chimpanzee / Mouse / Rat / Dog / Cow / Horse / Chicken
Human
GenBank:NM_005141 / - / 0.987 / 0.818 / 0.792 / 0.846 / 0.797 / 0.813 / 0.607
Chimpanzee
GenBank:XM_001137030 / 0.987 / - / 0.810 / 0.785 / 0.838 / 0.792 / 0.811 / 0.600
Mouse
GenBank:NM_181849 / 0.818 / 0.81 / - / 0.896 / 0.783 / 0.776 / 0.754 / 0.594
Rat
GenBank:NM_020071 / 0.792 / 0.785 / 0.896 / - / 0.758 / 0.753 / 0.738 / 0.588
Dog
GenBank:XM_848645 / 0.843 / 0.838 / 0.783 / 0.758 / - / 0.807 / 0.821 / 0.622
Cow
GenBank:XM_587666 / 0.797 / 0.792 / 0.776 / 0.753 / 0.807 / - / 0.756 / 0.598
Horse
GenBank:XM_001500955 / 0.813 / 0.811 / 0.754 / 0.738 / 0.821 / 0.756 / - / 0.600
Chicken
GenBank:XM_420369 / 0.607 / 0.600 / 0.594 / 0.588 / 0.622 / 0.598 / 0.600 / -

A similarity matrix between FGB protein sequences of two host species is shown. Identical sequences would score as 1.000 and two sequences that share no common sites would score as 0.000. GenBank accession numbers for each sequence used in the comparison are shown.

Table S6. Interspecies homology of FGG

Human / Chimpanzee / Mouse / Rat / Dog / Cow / Horse
Human
GenBank:NM_000509 / - / 0.922 / 0.821 / 0.814 / 0.852 / 0.837 / 08.57
Chimpanzee
GenBank:XM_001138780 / 0.992 / - / 0.821 / 0.812 / 0.854 / 0.837 / 0.856
Mouse
GenBank:NM_133862 / 0.821 / 0.821 / - / 0.907 / 0.782 / 0.770 / 0.774
Rat
GenBank:NM_012559 / 0.814 / 0.812 / 0.907 / - / 0.781 / 0.752 / 0.765
Dog
GenBank:XM_848659 / 0.852 / 0.854 / 0.782 / 0.781 / - / 0.837 / 0.857
Cow
GenBank:NM_173911 / 0.837 / 0.837 / 0.770 / 0.752 / 0.837 / - / 0.830
Horse
GenBank:XM_001914798 / 0.857 / 0.856 / 0.774 / 0.765 / 0.857 / 0.830 / -

A similarity matrix between FGG protein sequences of two host species is shown. Identical sequences would score as 1.000 and two sequences that share no common sites would score as 0.000. GenBank accession numbers for each sequence used in the comparison are shown.

Table S7. Interspecies homology of FN-1

Human / Chimpanzee / Mouse / Rat / Cow / Horse
Human
GenBank:NM_212476 / - / 0.992 / 0.864 / 0.865 / 0.897 / 0.905
Chimpanzee
GenBank:XM_516072 / 0.992 / - / 0.864 / 0.864 / 0.896 / 0.905
Mouse
GenBank:NM_010233 / 0.864 / 0.864 / - / 0.945 / 0.855 / 0.858
Rat
GenBank:CH474044 / 0.865 / 0.864 / 0.945 / - / 0.855 / 0.860
Cow
GenBank:XP_879240 / 0.897 / 0.896 / 0.855 / 0.855 / - / 0.907
Horse
GenBank:XM_001489104 / 0.905 / 0.905 / 0.858 / 0.860 / 0.907 / -

A similarity matrix between FN-1 protein sequences of two host species is shown. Identical sequences would score as 1.000 and two sequences that share no common sites would score as 0.000. GenBank accession numbers for each sequence used in the comparison are shown.

Table S8. Interspecies homology of PT

Human / Orangutan / Mouse / Rat / Cow / Pig / Horse / Chicken
Human
GenBank:NM_000552 / - / 0.948 / 0.809 / 0.791 / 0.812 / 0.828 / 0.815 / 0.609
Orangutan
GenBank:CR861038 / 0.948 / - / 0.781 / 0.768 / 0.779 / 0.799 / 0.794 / 0.596
Mouse
GenBank:NM_010168 / 0.809 / 0.781 / - / 0.933 / 0.769 / 0.796 / 0.782 / 0.629
Rat
GenBank:X52835 / 0.791 / 0.768 / 0.933 / - / 0.753 / 0.778 / 0.770 / 0.627
Cow
GenBank:NM_173877 / 0.812 / 0.779 / 0.769 / 0.753 / - / 0.849 / 0.788 / 0.616
Pig
GenBank:DQ530370 / 0.828 / 0.799 / 0.796 / 0.778 / 0.849 / - / 0.829 / 0.616
Horse
GenBank:XM_001490842 / 0.815 / 0.794 / 0.782 / 0.770 / 0.788 / 0.829 / - / 0.614
Chicken
GenBank:NM_204605 / 0.609 / 0.596 / 0.629 / 0.627 / 0.616 / 0.616 / 0.614 / -

A similarity matrix between PT protein sequences of two host species is shown. Identical sequences would score as 1.000 and two sequences that share no common sites would score as 0.000. GenBank accession numbers for each sequence used in the comparison are shown.

Table S9. Interspecies homology of vWF

Human / Chimpanzee / Mouse / Rat / Dog / Cow / Pig / Chicken
Human
GenBank:NM_000552 / - / 0.833 / 0.990 / 0.766 / 0.862 / 0.810 / 0.559 / 0.745
Chimpanzee
GenBank:XM_508945 / 0.833 / - / 0.832 / 0.737 / 0.829 / 0.911 / 0.551 / 0.720
Mouse
GenBank:NM_011708 / 0.990 / 0.832 / - / 0.766 / 0.862 / 0.808 / 0.560 / 0.745
Rat
GenBank:XM_342759 / 0.766 / 0.737 / 0.766 / - / 0.765 / 0.733 / 0.513 / 0.752
Dog
GenBank:NM_001002932 / 0.862 / 0.829 / 0.862 / 0.765 / - / 0.809 / 0.558 / 0.746
Cow
GenBank:XM_584169 / 0.810 / 0.911 / 0.808 / 0.733 / 0.809 / - / 0.545 / 0.713
Pig
GenBank:AF052036 / 0.559 / 0.551 / 0.560 / 0.513 / 0.558 / 0.545 / - / 0.491
Chicken
GenBank:XM_417223 / 0.745 / 0.720 / 0.745 / 0.752 / 0.746 / 0.713 / 0.491 / -

A similarity matrix between vWF protein sequences of two host species is shown. Identical sequences would score as 1.000 and two sequences that share no common sites would score as 0.000. GenBank accession numbers for each sequence used in the comparison are shown.