Aap Section on Critical Care

AAP SECTION ON CRITICAL CARE

2006 NEW INVESTIGATOR RESEARCH AWARD

APPLICATION

Dear Applicant:

Enclosed please find the application form, followed by the instructions, for the American Academy of Pediatrics’ Section on Critical Care New Investigator Research Award. One $10,00010,000 award will allow an individual during his or her pediatric critical care fellowship, or within 2 years of completing an accredited critical care fellowship, to gain research experience by conducting basic scientific or clinical research. You must be a current member of the AAP Section on Critical Care to qualify.

Please note that a brief 2-page pre-proposal is due by April 3, 2006.

Pre-proposals should be 2 pages in length (not including bibliography), single-spaced, using standard type (12 pitch = 12 characters per inch) and one-inch margins. The pre-proposal should provide an overview of the project and include the following components:

background

objective(s)

hypothesis

methods

estimated budget

The cover page must include the institution of the principal investigator, along with the address, telephone and fax numbers, as well as the principal investigator¹s e-mail address. Please submit an original pre-proposal, along with the Curriculum Vitae of the principal investigator, in addition to that of the proposed sponsor/mentor. Following review of the pre-proposals, selected applicants will be asked to submit a full proposal. Full applications will be solicited by May 1, 2006.

A complete copy of the full grant application will be due by July 5, 20022006.

Please send the pre-proposal electronically, and if subsequently requested, the full application, to:

Barry Markovitz, MD, MPH

If you have any further questions, please contact Dr Markovitz at the e-mail listed above or staff to the AAP Section on Critical Care, Sue Tellez, at

Thank you and good luck!

Sincerely,

Barry Markovitz, MD, MPH

Research Awards Chairperson

AAP Section on Critical Care

American Academy of PediatricsNEW INVESTIGATOR GRANT

Critical Care SectionAWARD APPLICATION

1. Application is made for one year award beginning September 1, 2006.
2. Name of applicant (last, first, middle)
3. Current address
(Department, School, Institution, Address) / 4. Institution where work will be done
(Department, School, Institution, Address)
Area Code / Number / Ext / Area Code / Number / Ext
5. Title of research project (must be limited to 60 letters and spaces)
6. Name, academic rank, and department of individual (sponsor) under whom research will be done
7.(a)Research involves biohazards:Yes ____ No ____ Date approved ______
(b)Research involves radioisotopes:Yes ____ No ____ Date approved ______
(c)Research involves human subjects:Yes ____ No ____ Date approved ______
(d)Research involves animal subjects:Yes ____ No ____ Date approved ______
(e)Is your institution accredited
by AAALAC?Yes ____ No ____ Effective date ______
(f)Does your institution have a current
PHS Animal Welfare Assurance?Yes ____ No ____ Date approved ______
ID# ______
REQUIRED VERIFICATION FOR THESE ITEMS IS DETAILED IN THE INSTRUCTIONS
8. Applicant (please type)(Signature)(Date)
Sponsor (please type)(Signature)(Date)
Department Head (please type)(Signature)(Date)
Fiscal Officer (please type)(Signature)(Date)
Institutional Officer (please type)(Signature)(Date)
NAME AND ADDRESS FOR FINANCIAL CORRESPONDENCE

With all signatures, please scan this page to email with full application or fax separately. See instructions page 35.

Principal Investigator ______

American Academy of PediatricsNEW INVESTIGATOR GRANT

Critical Care SectionAWARD APPLICATION

9. ABSTRACT

Principal Investigator ______

American Academy of PediatricsNEW INVESTIGATOR GRANT

Critical Care SectionAWARD APPLICATION

10. LAY RESEARCH SUMMARY

Name of Investigator (please type)LastFirstMiddle
Name and Address of Institution Where Work Will be Done:
Title of Project:
LAY RESEARCH SUMMARY (PART 1)
(To be written for the understanding of persons not trained in biomedical science, e.g. published directly in a local newspaper)

Principal Investigator ______

11. CURRICULUM VITAE

PRINCIPAL INVESTIGATOR

Name / Birth date (Mo., Day, Yr.)
Education (Begin with baccalaureate or other initial professional education, and include postdoctoral training.)
INSTITUTION AND LOCATIONDEGREEYEARFIELD OF STUDY
CONFERRED

Concluding with present position, list, in chronological order, previous employment, research experience, and honors. List, in chronological order, the titles and complete references to all publications (See instructions). DO NOT EXCEED TWO PAGES.

Principal Investigator ______

CURRICULUM VITAE

PRINCIPAL INVESTIGATOR

(Continued)

Principal Investigator ______

12. PRINCIPAL INVESTIGATOR’S CAREER PLANS IN PEDIATRIC CRITICAL CARE

Principal Investigator ______

13. OTHER PERSONNEL

Principal Investigator ______

14. CURRICULUM VITAE

SPONSOR

Name / Birth date (Mo., Day, Yr.)
Education (Begin with baccalaureate or other initial professional education, and include postdoctoral training.)
INSTITUTION AND LOCATIONDEGREEYEARFIELD OF STUDY
CONFERRED

Research and Professional Experience: Concluding with present position, list, in chronological order, previous employment, experience, and honors. Include present membership on any Federal Government public advisory committee. List, in chronological order, the titles and complete references to all publications during the past three years and to representative earlier publications pertinent to this application DO NOT EXCEED TWO PAGES.

Principal Investigator ______

CURRICULUM VITAE

SPONSOR

(Continued)

Principal Investigator ______

15. SPONSOR GRANT SUPPORT

Principal Investigator ______

16. TRAINEES OF SPONSOR

Principal Investigator ______

17. SPONSOR LETTER OF SUPPORT

[See page 36 (X.17) and page 39 (XIX.26) for specific instructions]

Principal Investigator ______

18. AWARD BUDGET ALLOCATION

PRINCIPAL INVESTIGATOR
SUPPLIES (ITEMIZE)
EQUIPMENT (ITEMIZE)
TOTAL / $10,000

Principal Investigator ______

19. AWARD BUDGET JUSTIFICATION

Principal Investigator ______

20. REMAINDER OF PROJECT BUDGET ALLOCATION

PERSONNEL

NAME / ROLE IN PROJECT / % EFFORT / SALARY & FRINGE / TOTAL / SOURCE OF FUNDS
SUPPLIES (ITEMIZE)
EQUIPMENT (ITEMIZE)
OTHER (ITEMIZE)
TOTAL

Principal Investigator ______

21. REMAINDER OF PROJECT BUDGET JUSTIFICATION

Principal Investigator ______

22.FACILITIES AVAILABLE

Mark the facilities to be used at the applicant organization and briefly indicate their capacities, pertinent capabilities, relative proximity and extent of availability to the project. Use “other” to describe the facilities at any other performance sites listed in item 9, page 1, and at sites for field studies. Using continuation pages if necessary, include an explanation of any consortium/contractual arrangements with other organizations.
[] Laboratory:
[] Clinical:
[] Animal:
[] Computer:
[] Office:
[] Other: ( ______)
MAJOR EQUIPMENT: List the most important equipment items already available for this project, noting the location and pertinent capabilities of each.
ADDITIONAL INFORMATION: Provide any other information describing the environment for the project. Identify support services such as consultants, secretaries, machine shop, and electronics shop, and the extent to which they will be available to the project.

Principal Investigator ______

1. SPECIFIC AIMS

Principal Investigator ______

2. BACKGROUND AND SIGNIFICANCE (Continued)

Principal Investigator ______

2. BACKGROUND AND SIGNIFICANCE (Continued)

Principal Investigator ______

3. PRELIMINARY STUDIES

Principal Investigator ______

3. PRELIMINARY STUDIES (Continued)

Principal Investigator ______

4. EXPERIMENTAL DESIGN AND METHODS

Principal Investigator ______

4. EXPERIMENTAL DESIGN AND METHODS (Continued)

Principal Investigator ______

4. EXPERIMENTAL DESIGN AND METHODS (Continued)

Principal Investigator ______

4. EXPERIMENTAL DESIGN AND METHODS (Continued)

Principal Investigator ______

5. DATA ANALYSIS

Principal Investigator ______

5. DATA ANALYSIS (Continued)

Principal Investigator ______

6. REFERENCES

Principal Investigator ______

American Academy of Pediatrics

Critical Care Section

New Investigator Award

AMERICAN ACADEMY OF PEDIATRICS

SECTION ON CRITICAL CARE MEDICINE

NEW INVESTIGATOR RESEARCH AWARD

GENERAL DESCRIPTION

The purpose of the American Academy of Pediatrics Section on Critical Care Medicine New Investigator Research Award is to promote understanding of critical illness and injury in children through clinical and/or laboratory research. The grant will provide support for a research project to an individual who has demonstrated aptitude for clinical or basic science during his or her pediatric critical care fellowship or during the first two years of post-fellowship experience as a junior faculty member in an academic setting.

The award will be judged on the following criteria:

• scientific merit

• clarity of the presentation

• likelihood of productivity by the investigator

• evidence of appropriate academic environment by the sponsor

• relevance to critical care

American Academy of Pediatrics

Critical Care Section

New Investigator Research Award Grant

SPECIFIC GUIDELINES

The Award

The Award is designed to provide funding for investigation generally involving basic or clinical research that will lead to improve understanding of critical illness or injury in children.

The Investigator

The investigator should be a physician who is in the first three years of pediatric critical care fellowship or someone who has completed an accredited critical care fellowship within the past 2 years. The investigator must have a MD, DO degree, or foreign equivalent. He or she also may have obtained a PhD degree. It is the investigator’s responsibility to spend at least 50% of their time devoted to research and without significant clinical responsibility during the funding period. The investigator must be a member of the AAP Section on Critical Care.

The Sponsor

The sponsor is the administrative link between the investigator and the intuition. The sponsor should be a full-time faculty member of an academic institution. He or she may be from the basic science or clinical faculty. and may have either a MD or PhD degree A sponsor should have demonstrated a commitment to training of scientists as evidenced by a list of previous trainees, and productivity as evidenced by publications, as well as peer reviewed grant support.

Change of Sponsor

If during the course of the year, the sponsor changes, the American Academy of Pediatrics must be notified in writing immediately. The investigator must designate another sponsor and supply the sponsor’s curriculum vitae (including previous trainees) as well as a letter from the sponsor indicating his or her willingness to serve in this capacity and specifically how any problems created by the change in sponsor will be solved.

Budget

The Award is for $10,000$10,000. There are no indirect costs. The funds may not be used for the investigator’s salary or for major equipment costing more than $500 per item. The funds may also not be used for consultant fees, service contracts, books, subscriptions to journals, construction, dues, items generally considered to be overhead (i.e. telephone, lights, etc.), travel, or publication costs. The funds may be used for salary other than the principal investigator’s (e.g. laboratory or research technician), patient related clinical tests, or minor supplies and equipment.

Grant funds may be re-budgeted. Any transfer of funds for a different expense in excess of $500 must be authorized by the American Academy of Pediatrics. The request must fully describe the transfer and how the funds will be used. This letter must be co-signed by the grantee institution’s fiscal officer as well as the principal investigator and sponsor. Subsequent financial reports must reference these transfers.

American Academy of Pediatrics

Critical Care Section

New Investigator Research Award Grant

Method of Payment

Grant payments are disbursed at the beginning of the funding period to the institution.

Concurrent Funding

The principal investigator may be eligible for this Award if he or she is receiving direct support from any other local, state, or national agency as long as the funds are used in conjunction with pre-existing support with no areas of duplication. A copy of the title, abstract, budget, and budget justification pages of all existing or pending grants must accompany this proposal. Project funding for supplies and equipment directed to the sponsor is permissible.

Grant Timetable

January 18, 2006January 1, 2002-Grant applications available.

April 3, 2006March 1, 2002 - Pre-proposals due.

May 1, 2006April 1, 2002 - Full applications solicited.

July 5, 2006June 1, 2002-Deadline for receipt of full applications.

Send to: Barry Markovitz, MD, MPH

August 1, 2006July 2, 2002-Notification to Investigator and Institution.

September 1, 2006August 1, 2002 -Initiation of the Award.

September 1, 2007 August 1, 2003 -Termination of the Award.

September 1, 2003October 1, 2007 -Scientific Progress Report due signed by Principal Investigator
and the Institutional Fiscal Officer.

November 2007-Presentation of Results at American Academy of Pediatrics, Critical
Care Section Annual Meeting

The Awardee is required to present his or her results during the annual meeting of the Critical Care Section of the American Academy of Pediatrics in the year of the grant termination. Since funds from the Award may not be used for travel, the Section on Critical Care will provide a separate travel stipend for this purpose following completion of the study.

American Academy of Pediatrics

Critical Care Section

New Investigator Research Award Grant

The Awardee will be eligible for the In-Training Award or Best Clinical or Scientific Abstract only if he/she submits the abstract in accordance with the AAP Scientific Session guidelines.

Scientific Progress Report

One month after the termination of the Award, a final scientific progress report must be submitted (maximum three pages single-spaced) including plans for future research in the area.

Grant Review

The Executive Committee of the American Academy of Pediatrics, Critical Care Section, will appoint a Chair and Subcommittee to review all grant proposals. After receipt of the applications, the chair will assign two reviewers to each proposal. The assigned reviewers will constitute the study section. The group will then meet to decide the relative priorities of the applications. One award per year will be made. Comments of reviewers will not accompany the decision.

American Academy of Pediatrics

Critical Care Section

New Investigator Research Award Grant

PREPARATION OF THE APPLICATION

General

Use standard fonts (12 point). Do not leave any area blank: indicate N/A or None if not applicable. Failure to follow instructions will result in return of the application and disqualification from consideration. Any questions should be addressed to either Dr Barry Markovitz, Research Awards Chairperson, at or Sue Tellez, AAP Section on Critical Care Manager, at

Special Instructions

I.Application face page

1-3 --Self explanatory.

4 --If the work institution is not the same as the academic institution, indicate name of the work institution with the complete address; otherwise, write “same.”

5 --Title - title cannot exceed sixty (60) letters and spaces. Do not use abbreviations.

6 --Self explanatory.

7 --Check appropriate box relating to experimentation with biohazards, radioisotopes, human subjects and/or animal subjects. If the answer to A, C, or D is “yes” and the research has been endorsed “by the appropriate institutional committee,” enter the date after “approved.” If the answer is “yes” and the project is pending review, enter the date scheduled for review followed by “P.” Written endorsement must be received by the American Academy of Pediatrics before the grant can begin on April 1st (see instruction #24).

8 --To be signed by the applicant, the sponsor, the department head, the institution academic official and the institutional fiscal officer of the institution where the work will be done.

Please submit a scanned copy of this page (and this page only – do not scan the entire application), with signatures, along with the application. Alternatively, you may fax the signed page to Dr. Markovitz at 314-454-2296.

II.Abstract

9 --The abstract should include a synopsis of the proposed research. It should begin with one or two introductory sentences on the scientific background of the proposal and then follow with a statement of the specific aims and hypotheses, the methods and procedures to be used, the expected data and the potential significance of the research.

American Academy of Pediatrics

Critical Care Section

New Investigator Research Award Grant

III.Lay summary

10 --This summary should be written for individuals not familiar with scientific work. It should be prepared for direct publication in a local newspaper.

IV.Curriculum vitae of principal investigator

11 --Self-explanatory. After a list of publications and abstracts, the principal investigator should list the title of any research done that did not lead to a publication and a one sentence description indicating the principal investigator’s role in the project.

V.Career Plans

12 --A statement should be made by the principal investigator indicating how the one year of funding provided by the American Academy of Pediatrics will relate to specific plans for the next five years and to general plans for a career in pediatric critical care beyond that time.

VI.Other personnel

13 --The name, degree, academic rank and department as well as a brief description of the role in the research project should be included for each member of the research team as well as consultants.

VII.Curriculum vitae of sponsor

14 --Self-explanatory.

VIII.Sponsor grant support during last five years.

15 --The title, role (principal investigator, collaborating investigator, etc.), percent effort, total amount of award and brief description of contribution to the project should be listed for each of the last five years.

IX.Trainees of the sponsor for the last five years.

16 --The name, degree, duration of training and brief description of supervisory role should be given for each of the trainees of the sponsor during the last five years.

X.Letter from sponsor.

17 --A supporting letter from the sponsor must accompany the application indicating full knowledge of the research plan the candidate has submitted. The letter from the sponsor should include assurance that the candidate will be permitted to spend least 50% of his or her time as pure research during the funding period. The letter should also indicate that appropriate research facilities will be made available. The last section should be a letter of recommendation indicating the unique facets of the principal investigator that qualify him or her for this Award as well as any potential weaknesses. [See XIX.26 for additional instructions]

American Academy of Pediatrics

Critical Care Section

New Investigator Research Award Grant

XI.Award budget allocation.

18 --See Budget page 2. The total may not exceed $10,000. It is permissible to devote 100% of the budget to either the personnel salary (except the PI’s) or supplies, but no more than $500 may be used for any one piece of equipment.

XII.Award budget justification.

19 --Each item over $50 must be justified separately. The budget justification will be considered along with the budget justification of the entire project (item #21) and the two must relate to each other.

XIII.Budget allocation for remainder of principal investigator’s project.