GREENVILLE HOSPITAL SYSTEM

SCIENTIFIC REVIEW OF RESEARCH PROTOCOLS INVOLVING HUMAN SUBJECTS

All protocols must undergo scientific review by a departmental research group or other designated authority prior to submission to the IRB. The review must involve individuals qualified to evaluate the scientific merit of the study being proposed. If the departmental research review group does not include individuals who are capable of evaluating the scientific merit of a particular proposal, it is the responsibility of the Medical Director of the Office of Research and Compliance Administration to have the protocol reviewed by an appropriate authority notinvolved in the study in question.

Principal Investigator: ______

Department or Medical Practice:______

Protocol Title: ______

______

______

1.Hypothesis is clearly stated. Yes No

  1. The scientific questions addressed in this protocol have

adequate merit to justify experimentation involving

human subjects. Yes No

  1. The study design is adequate to answer

the questions being asked. Yes No

  1. The potential risks of this study have been

accurately and fully described. Yes No

5.The study design minimizes risk to subjects. Yes No

  1. The investigators have adequate experience

to conduct the study. Yes No

Risk Assessment – choose one:

1. The study involves no more than minimal risk to participants.

2. The study involves more than minimal risk to participants.

The risk(s) represents a minor increase over minimal risk, or

The risk(s) represents more than a minor increase over minimal risk.

Benefits Assessment – choose one:

1. The study involves no prospect of direct benefit to individual participants, but

is likely to yield generalizable knowledge about the subject’s disorder or condition.

2. The study involves the prospect of direct benefit to individual participants.

Approved for submission to IRB

Return to Principal Investigator for changes

______

Signature of Departmental Research Group Chair Date

Version 3 November 20, 2009