PEG Products
Maya Chemical provides high quality PEG products with low polydispersity and low diol content. Functionally, including active PEG derivatives for amine PEGylation, active PEG derivatives for N-terminal PEGylation, and active PEG derivatives for thiol PEGylation. Structurally,including branched PEG derivatives, linearPEG derivatives,homobifunctionalPEG Derivatives,heterobifunctionalPEG Derivatives, and multi-arm PEG derivatives. PEG derivatives with different functional groups, customPEG derivatives, and PEG raw materialsare also available.
PRODUCTS LIST April 2009
PRODUCTS FOR AMINE PEGYLATION ...... 2
PRODUCTS FOR THIOL PEGYLATION ...... 2
PRODUCTS FOR N-TERMINAL
PEGYLATION ...... …………...... 3
OTHER LINEAR METHOXY PEG DERIVATIVES ...... ……………...... 3
HOMOBIFUNCTIONAL PEG DERIVATIVES ...... ……...... 3
HETEROBIFUNCTIONAL PEG DERIVATIVES ...... …………...... 4
MULTI-ARM PEG DERIVATIVES ...... 5
LINEAR METHOXY PEG RAW MATERIALS ...... ………….... 7
MULTI-ARM PEG RAW MATERIALS ...... 7
Other molecular weights are available.
Custom synthesis is available.
Quotations for bulk orders are available.
cGMP quality is available.
To order please contact:
Maya Chemical Company
Tel: 02-28586296 Fax: 02-28588517
Email:
Products for Amine PEGylation
Item Number / Product NameY-NHS-40K / Y-shape PEG NHS Ester, MW 40000
GLUC-NHS-35K / Glucose PEG NHS Ester, MW 35000
GALA-NHS-35K / Galactose PEG NHS Ester, MW 35000
M-SCM-2000 / Methoxy PEG Succinimidyl Carboxymethyl Ester, MW 2000
M-SCM-5000 / Methoxy PEG Succinimidyl Carboxymethyl Ester, MW 5000
M-SCM-20K / Methoxy PEG Succinimidyl Carboxymethyl Ester, MW 20000
M-SCM-30K / Methoxy PEG Succinimidyl Carboxymethyl Ester, MW 30000
M-SCM-35K / Methoxy PEG Succinimidyl Carboxymethyl Ester, MW 35000
M-SCM-40K / Methoxy PEG Succinimidyl Carboxymethyl Ester, MW 40000
Products for Thiol PEGylation
Item Number / Product NameY-MAL-40K / Y-shape PEG Maleimide, MW 40000
M-MAL-2000 / Methoxy PEG Maleimide, MW 2000
M-MAL-5000 / Methoxy PEG Maleimide, MW 5000
M-MAL-20K / Methoxy PEG Maleimide, MW 20000
M-MAL-30K / Methoxy PEG Maleimide, MW 30000
M-MAL-40K / Methoxy PEG Maleimide, MW 40000
M-VS-5000 / Methoxy PEG Vinylsulfone, MW 5000
M-VS-20K / Methoxy PEG Vinylsulfone, MW 20000
M-SH-5000 / Methoxy PEG Thiol, MW 5000
M-SH-20K / Methoxy PEG Thiol, MW 20000
To order, please contact us at
Products for N-Terminal PEGylation
Item Number / Product NameY-ALD-40K / Y-shape PEG Aldehyde, MW 40000
M-ALD-5000 / Methoxy PEG Propionaldehyde, MW 5000
M-ALD-20K / Methoxy PEG Propionaldehyde, MW 20000
M-ALD-30K / Methoxy PEG Propionaldehyde, MW 30000
M-ALD-40K / Methoxy PEG Propionaldehyde, MW 40000
Other Linear Methoxy PEG Derivatives
Item Number / Product NameM-NH2-2000 / Methoxy PEG Amine, HCl Salt, MW 2000
M-NH2-5000 / Methoxy PEG Amine, HCl Salt, MW 5000
M-NH2-20K / Methoxy PEG Amine, HCl Salt, MW 20000
M-NH2-30K / Methoxy PEG Amine, HCl Salt, MW 30000
M-NH2-40K / Methoxy PEG Amine, HCl Salt, MW 40000
M-HZ-5000 / Methoxy PEG Hydrazide, MW 5000
M-HZ-20K / Methoxy PEG Hydrazide, MW 20000
Homobifunctional PEG Derivatives
Item Number / Product NameCOOH-PEG2000-COOH / Carboxyl PEG Carboxyl, MW 2000
COOH-PEG3500-COOH / Carboxyl PEG Carboxyl, MW 3500
COOH-PEG5000-COOH / Carboxyl PEG Carboxyl, MW 5000
COOH-PEG7500-COOH / Carboxyl PEG Carboxyl, MW 7500
NH2-PEG2000-NH2 / Amine PEG Amine, HCl Salt, MW 2000
NH2-PEG3500-NH2 / Amine PEG Amine, HCl Salt, MW 3500
NH2-PEG5000-NH2 / Amine PEG Amine, HCl Salt, MW 5000
NH2-PEG7500-NH2 / Amine PEG Amine, HCl Salt, MW 7500
MAL-PEG2000-MAL / Maleimide PEG Maleimide, MW 2000
MAL-PEG3500-MAL / Maleimide PEG Maleimide, MW 3500
MAL-PEG5000-MAL / Maleimide PEG Maleimide, MW 5000
MAL-PEG7500-MAL / Maleimide PEG Maleimide, MW 7500
To order, please contact us at
Heterobifunctional PEG Derivatives
Item Number / Product NameHO-PEG2000-COOH / Hydroxyl PEG Carboxyl, MW 2000
HO-PEG3500-COOH / Hydroxyl PEG Carboxyl, MW 3500
HO-PEG5000-COOH / Hydroxyl PEG Carboxyl, MW 5000
HO-PEG7500-COOH / Hydroxyl PEG Carboxyl, MW 7500
HO-PEG2000-NH2 / Hydroxyl PEG Amine, HCl Salt, MW 2000
HO-PEG3500-NH2 / Hydroxyl PEG Amine, HCl Salt, MW 3500
HO-PEG5000-NH2 / Hydroxyl PEG Amine, HCl Salt, MW 5000
HO-PEG7500-NH2 / Hydroxyl PEG Amine, HCl Salt, MW 7500
TBOC-PEG2000-NH2 / t-Boc Amine PEG Amine, HCl Salt, MW 2000
TBOC-PEG3500-NH2 / t-Boc Amine PEG Amine, HCl Salt, MW 3500
TBOC-PEG5000-NH2 / t-Boc Amine PEG Amine, HCl Salt, MW 5000
TBOC-PEG7500-NH2 / t-Boc Amine PEG Amine, HCl Salt, MW 7500
NH2-PEG2000-COOH / Amine PEG Carboxyl, HCl Salt, MW 2000
NH2-PEG3500-COOH / Amine PEG Carboxyl, HCl Salt, MW 3500
NH2-PEG5000-COOH / Amine PEG Carboxyl, HCl Salt, MW 5000
NH2-PEG7500-COOH / Amine PEG Carboxyl, HCl Salt, MW 7500
TBOC-PEG2000-NHS / t-Boc Amine PEG NHS Ester, MW 2000
TBOC-PEG3500-NHS / t-Boc Amine PEG NHS Ester, MW 3500
TBOC-PEG5000-NHS / t-Boc Amine PEG NHS Ester, MW 5000
TBOC-PEG7500-NHS / t-Boc Amine PEG NHS Ester, MW 7500
FMOC-PEG2000-NHS / Fmoc Amine PEG NHS Ester, MW 2000
FMOC-PEG3500-NHS / Fmoc Amine PEG NHS Ester, MW 3500
FMOC-PEG5000-NHS / Fmoc Amine PEG NHS Ester, MW 5000
FMOC-PEG7500-NHS / Fmoc Amine PEG NHS Ester, MW 7500
HS-PEG3500-COOH / Thiol PEG Carboxyl, MW 3500
HS-PEG5000-COOH / Thiol PEG Carboxyl, MW 5000
ACLT-PEG2000-NHS / Acrylate PEG NHS Ester, MW 2000
ACLT-PEG3500-NHS / Acrylate PEG NHS Ester, MW 3500
ACLT-PEG5000-NHS / Acrylate PEG NHS Ester, MW 5000
ACLT-PEG7500-NHS / Acrylate PEG NHS Ester, MW 7500
MAL-PEG2000-NH2 / Maleimide PEG Amine, TFA Salt, MW 2000
MAL-PEG3500-NH2 / Maleimide PEG Amine, TFA Salt, MW 3500
MAL-PEG5000-NH2 / Maleimide PEG Amine, TFA Salt, MW 5000
MAL-PEG7500-NH2 / Maleimide PEG Amine, TFA Salt, MW 7500
MAL-PEG2000-NHS / Maleimide PEG NHS Ester, MW 2000
MAL-PEG3500-NHS / Maleimide PEG NHS Ester, MW 3500
MAL-PEG5000-NHS / Maleimide PEG NHS Ester, MW 5000
MAL-PEG7500-NHS / Maleimide PEG NHS Ester, MW 7500
MAL-PEG2000-COOH / Maleimide PEG Carboxyl, MW 2000
MAL-PEG3500-COOH / Maleimide PEG Carboxyl, MW 3500
MAL-PEG5000-COOH / Maleimide PEG Carboxyl, MW 5000
MAL-PEG7500-COOH / Maleimide PEG Carboxyl, MW 7500
BIOTIN-PEG2000-NHS / Biotin PEG NHS Ester, MW 2000
BIOTIN-PEG3500-NHS / Biotin PEG NHS Ester, MW 3500
BIOTIN-PEG5000-NHS / Biotin PEG NHS Ester, MW 5000
BIOTIN-PEG7500-NHS / Biotin PEG NHS Ester, MW 7500
BIOTIN-PEG2000-MAL / Biotin PEG Maleimide, MW 2000
BIOTIN-PEG3500-MAL / Biotin PEG Maleimide, MW 3500
BIOTIN-PEG5000-MAL / Biotin PEG Maleimide, MW 5000
BIOTIN-PEG7500-MAL / Biotin PEG Maleimide, MW 7500
OPSS-PEG3500-NHS / OPSS PEG NHS Ester, MW 3500
OPSS-PEG5000-NHS / OPSS PEG NHS Ester, MW 5000
The NHS esters in this category are all Succinimidyl Carboxymethyl Ester (SCM).
Multi-arm PEG Derivatives
4ARM-PEG Derivatives (pentaerythritol core)
Item Number / Product Name4ARM-NH2-5000 / 4arm PEG Amine, HCl Salt, MW 5000
4ARM-NH2-10K / 4arm PEG Amine, HCl Salt, MW 10000
4ARM-NH2-20K / 4arm PEG Amine, HCl Salt, MW 20000
4ARM-COOH-10K / 4arm PEG Carboxyl, MW 10000
4ARM-COOH-20K / 4arm PEG Carboxyl, MW 20000
4ARM-MAL-10K / 4arm PEG Maleimide, MW 10000
4ARM-MAL-20K / 4arm PEG Maleimide, MW 20000
4ARM-SS-10K / 4arm PEG Succinimidyl Succinate, MW 10000
4ARM-SS-20K / 4arm PEG Succinimidyl Succinate, MW 20000
4ARM-SG-10K / 4arm PEG Succinimidyl Glutarate, MW 10000
4ARM-SG-20K / 4arm PEG Succinimidyl Glutarate, MW 20000
To order, please contact us at
8ARM-PEG Derivatives (hexaglycerin core)
Item Number / Product Name8ARM-NH2-10K / 8arm PEG Amine, HCl Salt, MW 10000
8ARM-NH2-20K / 8arm PEG Amine, HCl Salt, MW 20000
8ARM-NH2-40K / 8arm PEG Amine, HCl Salt, MW 40000
8ARM-COOH-10K / 8arm PEG Carboxyl, MW 10000
8ARM-COOH-20K / 8arm PEG Carboxyl, MW 20000
8ARM-COOH-40K / 8arm PEG Carboxyl, MW 40000
8ARM-SS-10K / 8arm PEG Succinimidyl Succinate, MW 10000
8ARM-SS-20K / 8arm PEG Succinimidyl Succinate, MW 20000
8ARM-SS-40K / 8arm PEG Succinimidyl Succinate, MW 40000
8ARM-SG-10K / 8arm PEG Succinimidyl Glutarate, MW 10000
8ARM-SG-15K / 8arm PEG Succinimidyl Glutarate, MW 15000
8ARM-SG-20K / 8arm PEG Succinimidyl Glutarate, MW 20000
8ARM-SG-40K / 8arm PEG Succinimidyl Glutarate, MW 40000
8ARM-PEG Derivatives (tripentaerythritol core)
Item Number / Product Name8ARM(TP)-NH2-10K / 8arm PEG Amine, HCl Salt, MW 10000
8ARM(TP)-NH2-20K / 8arm PEG Amine, HCl Salt, MW 20000
8ARM(TP)-NH2-40K / 8arm PEG Amine, HCl Salt, MW 40000
8ARM(TP)-COOH-10K / 8arm PEG Carboxyl, MW 10000
8ARM(TP)-COOH-20K / 8arm PEG Carboxyl, MW 20000
8ARM(TP)-COOH-40K / 8arm PEG Carboxyl, MW 40000
8ARM(TP)-SS-10K / 8arm PEG Succinimidyl Succinate, MW 10000
8ARM(TP)-SS-20K / 8arm PEG Succinimidyl Succinate, MW 20000
8ARM(TP)-SS-40K / 8arm PEG Succinimidyl Succinate, MW 40000
8ARM(TP)-SG-10K / 8arm PEG Succinimidyl Glutarate, MW 10000
8ARM(TP)-SG-15K / 8arm PEG Succinimidyl Glutarate, MW 15000
8ARM(TP)-SG-20K / 8arm PEG Succinimidyl Glutarate, MW 20000
8ARM(TP)-SG-40K / 8arm PEG Succinimidyl Glutarate, MW 40000
To order, please contact us at
Linear Methoxy PEG Raw Materials
Item Number / Product NameM-PEG-5000 / Methoxy Polyethylene Glylcol, MW 5000
M-PEG-10K / Methoxy Polyethylene Glylcol, MW 10000
M-PEG-20K / Methoxy Polyethylene Glylcol, MW 20000
M-PEG-30K / Methoxy Polyethylene Glylcol, MW 30000
M-PEG-40K / Methoxy Polyethylene Glylcol, MW 40000
Multi-Arm PEG Raw Materials
4ARM-PEG Raw Materials (pentaerythritol core)
Item Number / Product Name4ARM-PEG-2000 / 4arm Polyethylene Glycol, MW 2000
4ARM-PEG-5000 / 4arm Polyethylene Glycol, MW 5000
4ARM-PEG-10K / 4arm Polyethylene Glycol, MW 10000
4ARM-PEG-15K / 4arm Polyethylene Glycol, MW 15000
4ARM-PEG-20K / 4arm Polyethylene Glycol, MW 20000
8ARM-PEG Raw Materials (hexaglycerin core)
Item Number / Product Name8ARM-PEG-10K / 8arm Polyethylene Glycol, MW 10000
8ARM-PEG-15K / 8arm Polyethylene Glycol, MW 15000
8ARM-PEG-20K / 8arm Polyethylene Glycol, MW 20000
8ARM-PEG-40K / 8arm Polyethylene Glycol, MW 40000
8ARM-PEG Raw Materials (tripentaerythritol core)
Item Number / Product Name8ARM(TP)-PEG-10K / 8arm Polyethylene Glycol, MW 10000
8ARM(TP)-PEG-15K / 8arm Polyethylene Glycol, MW 15000
8ARM(TP)-PEG-20K / 8arm Polyethylene Glycol, MW 20000
8ARM(TP)-PEG-40K / 8arm Polyethylene Glycol, MW 40000
To order, please contact us at
Branched PEG Derivatives for PEGylation
Branched PEG derivatives, also known as "Y-shaped" PEG derivatives, contain two linear methoxy PEG chain attached to a central core. The sterically bulky structure of these "Y-shaped" PEG derivatives will facilitate the single point attachment of the modified molecules.
The typical structure of "Y-shaped" branched PEG is as the following:
Maya now provides the following three kinds of "Y-shaped" PEG derivatives. Y-NHS-40K is used for amine PEGylation, Y-MAL-40K is used for thiol PEGylation, and Y-ALD-40K is for N-terminal PEGylation.
"Y-shaped" PEG derivatives are chemically purified during synthesis so that they are low in polydispersity and are essentially free of activated bifunctional PEG side products.
For Amine PEGylation
Y-NHS-40K: Y-Shape PEG NHS Ester, MW 40000
This "Y-shape" NHS ester will react with the amino group of lysine(s) or the N-terminal amine in biological active molecules to produce a stable amide linkage(s). This NHS ester will couplewith the targeted molecules at pH 7-8. The PEGylation reaction can be finished in about 1 hour.
Average molecular weight of this product is 40,000 Da. Substitution of this product is95% or greater. This product is basically free of activated bifunctional PEG side products.
ForThiol PEGylation
Y-MAL-40K: Y-Shape PEG Maleimide, MW 40000
This "Y-shape" maleimide will react with the thiol groups in biological active molecules to generates a stable 3-thiosuccinimidyl ether linkage. This maleimide will couplewith the targeted molecules at pH 5.0-6.5 in the presence of other functional groups.
Average molecular weight of this product is 40,000 Da. Substitution of this product is 90% or greater. This product is basically free of activated bifunctional PEG side products.
ForN-Terminal PEGylation
Y-ALD-40K: Y-Shape PEG Aldehyde, MW 40000
This "Y-shape" aldehyde will preferably react with the N-terminal amine in biological active molecules to produce a stable amine linkage in the presence of a reducing reagent such as sodium cyanoborohydride. This aldehyde will couple with the N-terminal amine of the targeted molecules at pH 5-8.
Average molecular weight of this product is 40,000 Da. Substitution of this product is90% or greater. This product is basically free of activated bifunctional PEG side products.
To order, please contact us at .
PEG Derivatives Custom Synthesis
Branched PEG derivatives, also known as "Y-shaped" PEG derivatives, contain two linear methoxy PEG chain attached to a central core. The sterically bulky structure of these "Y-shaped" PEG derivatives will facilitate the single point attachment of the modified molecules. Maya provides branched PEG derivatives for amine pegylatin, thiol pegylation, and N-terminus PEGylation. JenKem's regular branched PEG products include:
Y-NHS-40K, Y-shape PEG NHS Ester, MW 40000
Y-MAL-40K, Y-shape PEG Maleimide, MW 40000
Y-ALD-40K, Y-shape PEG Aldehyde, MW 40000
Linear Monofunctional PEG Derivatives For PEGylation
Linear monofunctional PEG derivatives have a reactive group at one end of the PEG andthe other end is capped with a methoxy group or a sugar group.
Linear monofunctional PEG derivatives have the following general structure::
CAP-PEG - X
where X is the functional group or active group
and CAP can be either a methoxy group or a sugar molecule
Two patented high molecular weight linear monofunctional PEG derivatives, GLUC-NHS-35K and GALA-NHS-35Kare provided.Theyare both used for amine PEGylation.
For Amine PEGylation
The following linear PEG NHS esters as regular products meet with your different PEGylation requirements. Other PEG NHS esters with different molecular weights are available through custom synthesis.
GLUC-NHS-35K: Glucose PEG NHS Ester, MW 35000
ThisN-hydroxysuccinimide (or NHS) ester will react with the amino group of lysine(s) or the N-terminal amine in biological active molecules to produce a stable amide linkage(s). The presence of glucose group will increase the selectivity of the PEGylation reaction. GLUC-NHS-35K will couple to the targeted molecules at pH 7-8. The PEGylation reaction can be finished in about 1 hour.
The average molecular weight of GLUC-NHS-35K is 35,000 Da. Substitution is 90% or greater.This product is basically free of active difunctional PEG impurities.
GALA-NHS-35K: Glucose PEG NHS Ester, MW 35000
ThisN-hydroxysuccinimide (or NHS) ester will react with the amino group of lysine(s) or the N-terminal amine in biological active molecules to produce a stable amide linkage(s). The presence of galactose group will increase the selectivity of the PEGylation reaction. GALA-NHS-35K will couplewith the targeted molecules at pH 7-8. The PEGylation reaction can be finished in about 1 hour.
The average molecular weight of GALA-NHS-35K is 35,000 Da. Substitution is 90% or greater. This product is basically free of active difunctional PEG impurities.
M-PEG-SCM: Methoxy PEG Succinimidyl Carboxymethyl Ester, MW 2000, MW 5000, MW 20000, MW 30000, MW 35000, MW 40000
ThisN-hydroxysuccinimide (or NHS) ester will react with the amino group of lysine(s) or the N-terminal amine in biological active molecules to produce a stable amide linkage(s). This NHS ester will couplewith the targeted molecules at pH 7-8. The PEGylation reaction can be finished in about 1 hour. Substitution of M-SCM-20K is95% or greater. M-PEG-SCM is basically free of active difunctional PEG impurities.
For Thiol PEGylation
M-PEG-MAL: Methoxy PEG Maleimide, MW 2000, MW 5000, MW 20000, MW 30000, MW 40000
M-PEG-MALreacts with the thiol groupsoncystein side chainsinproteins and peptidesto generates a stable 3-thiosuccinimidyl ether linkage. This maleimide will couplewith the targeted molecules at about pH 5.0-6.5 in the presence of other functional groups. Substitution of M-PEG-MAL is90% or greater.
M-PEG-VS: Methoxy PEG Vinylsulfone, MW 5000, MW20000
Sulfhydryl additon to the vinylsulfonegenerates a stabel beta-thiosulfonyl linkage. Vinylsulfone is stable in aqueous solution for a long time at high pH. Substitution of M-PEG-VS is90% or greater. Purity of M-VS-PEG is 95% or greater.
M-PEG-SH: Methoxy PEG Thiol, MW 5000, MW 20000
M-PEG-SHreacts with the thiol groupsoncystein side chainsinproteins and peptidesto generates a disulfide-bridged polymer conjugate.Substitution ofM-PEG-SHis90% or greater. Purityof M-SH-PEG is 90% or greater.
ForN-Terminal PEGylation
M-PEG-ALD: Methoxy PEG Propionaldehyde, MW 5000, MW 20000, MW 30000, MW 40000
M-PEG-ALD preferably reacts with the N-terminal amine in biological active molecules to produce a stable amine linkage in the presence of a reducing reagent such as sodium cyanoborohydride. This aldehyde will couplewith the N-terminal amine of the targeted molecules at pH 5-8. Substitution ofM-PEG-ALDis95% or greater. Purityof M-PEG-ALD is 95% or greater.
Other Linear Methoxy PEG Derivative
M-NH2-PEG: Methoxy PEG Amine, HCl Salt, MW 2000, MW 5000, MW 20000, MW 30,000, MW 40,000
Substitution ofM-NH2-20Kis95% or greater. The HCl Salt form provides stability in the solid form.
M-HZ-PEG: Methoxy PEGHydrazide, MW 5000,MW20000
To order, please contact us at
Other molecularsweights are available.
Quotations for bulk ordersare available.
PEG Derivatives Custom Synthesis
Linear monofunctional PEG derivatives have a reactive group at one end of the PEG. The other end is capped with a methoxy group or a sugar group. We providelinear PEG derivatives for amine pegylatin, thiol pegylation, and N-terminus PEGylation. Regular linear monofunctional PEG derivatives include:
GLUC-NHS-35K: Glucose PEG NHS Ester, MW 35000
GALA-NHS-35K: Glucose PEG NHS Ester, MW 35000
M-SCM-PEG: Methoxy PEG Succinimidyl Carboxymethyl Ester, MW 2000, MW 5000, MW 20000, MW 30000, MW 35000, MW 40000
M-PEG-MAL: Methoxy PEG Maleimide, MW 2000, MW 5000, MW 20000, MW 30000, MW 40000
M-PEG-VS: Methoxy PEG Vinylsulfone, MW 5000, MW20000
M-PEG-SH: Methoxy PEG Thiol, MW 5000, MW 20000
M-PEG-ALD: Methoxy PEG Propionaldehyde, MW 5000, MW 20000, MW 30000, MW 40000
M-NH2-PEG: Methoxy PEG Amine, HCl Salt,MW 2000,MW 5000, MW 20000, MW 30000, MW 40000
M-HZ-PEG: Methoxy PEG Hydrazide, MW 5000, MW 20000
HomobifunctionalPEG Derivatives
COOH-PEG-COOH:Carboxyl PEG Carboxyl, MW 2000, MW 3500, MW 5000, and MW 7500
NH2-PEG-NH2:Amine PEG Amine, HCl Salt, MW 2000,MW 3500, MW 5000, and MW 7500
MAL-PEG-MAL:Maleimide PEG Maleimide, MW 2000, MW 3500, MW 5000, and MW 7500
To order, please contact us at
Other molecular weights are available.
Quotations for bulk ordersare available.
PEG Derivatives Custom Synthesis
Various kinds of linear homobifunctional PEG derivatives. Regular homobifunctional PEG derivatives include:
COOH-PEG-COOH, MW 2000, MW 3500, MW 5000, MW 7500
NH2-PEG-NH2, MW 2000, MW 3500, MW 5000, MW 7500
MAL-PEG-MAL, MW 2000, MW 3500, MW 5000, MW 7500
HeterobifunctionalPEG Derivatives
Heterobifunctional PEG derivativesare useful as cross-linking agents or as spacers between two differententities. The PEG moiety in the heterobifunctional PEG derivatives provides water solutility, biocompatibility, and flexibility.
Heterobifunctional PEG derivatives have the following general structure:
X - PEG - Y
where X and Y aretwodifferentfunctional groups or active groups
HO-PEG-COOH: Hydroxyl PEG Carboxyl, MW 2000, MW 3500, MW 5000, MW 7500
These PEG derivativesalso called PEG mono acids. PEG mono acids are chromatographically purified with apurity of 95%or greater.
HS-PEG-COOH:Thiol PEG Carboxyl, MW 3500, MW 5000
HO-PEG-NH2: Hydroxyl PEG Amine, HCl Salt, MW 2000, MW 3500, MW 5000, MW 7500
These PEG derivativesalso called PEG mono amines. PEG monoamines are chromatographically purified with apurity of 95%or greater. The HCl salt form provides stability in the solid form.
TBOC-PEG-NH2:t-Boc Amine PEG Amine, HCl Salt, MW 2000, MW 3500, MW 5000, MW 7500
TBOC-PEG-NH2 has a substitution of 95% or greater attBOC end and 95% or greater atNH2 end.
NH2-PEG-COOH: Amine PEG Carboxyl, HCl Salt,MW 2000, MW 3500, MW 5000, MW 7500
These PEG derivativesalso called PEGamino acids. PEG aminoacids are chromatographically purified with apurity of 95%or greater at each end group.
TBOC-PEG-NHS: t-Boc Amine PEG NHS Ester,MW 2000, MW 3500, MW 5000, MW 7500
TBOC-PEG-NHS has a substitution of 90% or greater attBOC end and 90% or greater at NHS ester end.
FMOC-PEG-NHS:Fmoc Amine PEG NHS Ester,MW 2000, MW 3500, MW 5000, MW 7500
FMOC-PEG-NHS has a substitution of 90% or greater atFmoc end and 90% or greater at NHS ester end.
ACLT-PEG-NHS: Acrylate PEG NHS Ester, MW 2000, MW 3500, MW 5000, MW 7500
The ACLT-PEG-NHS esters is light sensitive and will cross-link with exposure to ultraviolet light. ACLT-PEG-NHS has a substitution of 90% or greater at acrylate end and 95% or greater at NHS ester end.
MAL-PEG-COOH: Maleimide PEG Carboxyl, MW 2000, MW 3500, MW 5000, MW 7500
MAL-PEG-COOH has a substitution of 90% or greater atmaleimide end and 95% or greater atCOOH end.
MAL-PEG-NH2: MaleimidePEG Amine, TFA Salt, MW 2000, MW 3500, MW 5000, MW 7500
MAL-PEG-NH2 has a substitution of 90% or greater atmaleimide end and 95% or greater at amine end.
MAL-PEG-NHS: Maleimide PEG NHS Ester, MW 2000, MW 3500, MW 5000, MW 7500
MAL-PEG-NHS has a substitution of 90% or greater atmaleimide end and 95% or greater at NHS ester end.
BIOTIN-PEG-NHS: Biotin PEG NHS Ester, MW 2000, MW 3500, MW 5000, MW 7500