Jan, Yuh-Nung-1
CURRICULUM VITAE
Name:Yuh Nung Jan
Current TitleJack and DeLoris Lange Professor of Molecular Physiology
Investigator, Howard Hughes Medical Institute
Department:Departments of Physiology, Biochemistry and Biophysics
University of California, San Francisco
San Francisco, CA 94143-0725
Office Phone:(415) 476-8747
Email:
Education:
B.Sc. in Physics / 1967 / National Taiwan University, Department of Physics (1963-1967)M.Sc. in Physics / 1970 / California Institute of Technology, Division of Physics, Mathematics and Astronomy (1968-1970)
Ph.D. in Biophysics and Physics / 1974 / California Institute of Technology, Division of Biology (1970-1974), Dr. Max Delbrück, Thesis Advisor
MILITARY SERVICE (COMPULSORY) / 1967-1968 / Communication and Electronics Officer, Second Lieutenant, Signal Corp, Air Force (Taiwan)
Teaching and Research Appointments:
Postdoctoral Research Fellow1974-1977
Dr. Seymour Benzer (Sponsor)
California Institute of Technology
Postdoctoral Research Fellow1977-1979
Dr. Steve W. Kuffler (Sponsor)
Department of Neurobiology
Harvard Medical School
Assistant Professor of Physiology19791983
University of California, San Francisco
Associate Professor of Physiology and19831985
Biochemistry, University of California,
San Francisco
Instructor, “Neurobiology of Drosophila” 19841987
Cold Spring Harbor Summer Course
Investigator, Howard Hughes Medical Institute1984-present
Professor of Physiology and Biochemistry1985present
University of California, San Francisco
Scholar in residence1989
“Neurobiology” Woods Hole Summer Course
Jack and DeLoris Lange Endowed Chair in1999-present
Molecular Physiology, University of California,
San Francisco
Awards/Honors:
Scottish Rite Schizophrenia Research Program Fellowship19741976
Muscular Dystrophy Association Postdoctoral Fellowship19761978
McKnight Scholar Award19781981
W. Alden Spencer Award and Lectureship, Columbia University1988
38th Faculty Lecturer Award, University of California, San Francisco1995
Elected member, National Academy of Sciences, U.S.A. 1996
Elected member, Academia Sinica (Taiwan)1998
K.S. Cole Award, Biophysical Society 2004
Distinguished Alumni Award, California Institute of Technology2006
SCBA Presidential Award2006
Jan Lab Symposium2006
Elected fellow, American Academy of Arts and Sciences2007
Outstanding Mentorship Award, The Postdoctoral Scholar’s
Association of UCSF 2007
Ralph Gerard Prize, Society for Neuroscience 2009
Javits Neuroscience Investigator Award, NINDS, NIH2010
Edward. M. Scolnick Prize in Neuroscience, Massachusetts Institute2010
of Technology
NARSAD Distinguished Investigator Award2010
Special Lectures/Keynote Lectures:
SCBA 5th International Symposium, Keynote Speaker, Baltimore1993
Karolinska Research Lecture, Nobel Forum, Stockholm, Sweden1997
Harvey Lecture, New York1998
The Stephen W. Kuffler Lecture, Harvard Medical School, Boston1999
Eighth Symposium on Recent Advances in Cellular and Molecular Biology.
Chinese Society of Cell and Molecular Biology, Keynote Lecture, Taiwan2000
SCBA 10th International Symposium, Keynote Speaker, Beijing2004
Keystone Symposia "Cell Polarity and Asymmetric Cell Divisions",
Keynote Speaker, Coeur d'Alene, Idaho2005
University of Utah Neuroscience Snowbird Symposium,
Keynote Speaker, Utah2005
International Symposium on Epithelia Organization and Organ Development,
Keynote speaker, Max Delbrück Center, Berlin, Germany2006
SCBA 11th International Symposium, Keynote Speaker, San Francisco2006
Liu Lecture, University of Pennsylvania School of Medicine, Philadelphia2006
European Science Foundation-EMBO Symposium “Cell Polarity and
Membrane Traffic”, Keynote Speaker, Saint Feliu de Guixols, Spain2009
Membership:
American Society of Cell Biology
Genetics Society of America
Society of Chinese Bioscientists in America
Society for Developmental Biology
Society for Neuroscience
Professional Service:
Editorial Board: Neuron, 1992-1994; Developmental Biology, 1995-2001; Molecular and Cellular Neuroscience, 1995-present; Genes and Development, 1996-present; Development, 1999-2004; Developmental Cell, 2001-present; PNAS, 2008-present
Co-Editor: Current Opinion of Cell Biology, Membrane Permeability 1994, 1997 (with L.Y. Jan); Current Opinion of Neurobiology, Neural Development 1997 (with A. Lumsden)
Reviewer (more than 50 per year) for various journals, mainly Genes and Development, Cell, Nature, Neuron, Development, Developmental Cell, Current Biology, PLoS, Journal of Neurosciene, Nature Neuroscience,Nature Cell Biology, PNAS and Science.
ad hoc reviewer of National Science Foundation, National Institute of Health, International Human Frontier Science Program Organization (Strasbourg), Academia Sinica (Taiwan), Swiss National Science Foundation, The Wellcome Trust (UK), and MRC (UK)
Postdoctoral Fellowship Selection Committee, American Cancer Society, California Chapter
(1994-1996)
Academia Sinica Investigator Selection Committee (2004)
RIKEN Brain Science Institute, Evaluation committee (2007)
Institute of Physics, Academia Sinica Advisory Committee, 2008-present
Co-organizer, Keystone “Stem Cells, Origins, Fates, and Functions” meeting, 2002 (with F. Gage and B. Hogan).
Co-organizer, Janelia Conference, HHMI “Dendrites: Development and Plasticity” meeting, 2008 (with L. Jan And J. Magee)
Mentoring:
More than 10 graduate students and 50 postdocs have trained in my lab. Many went on to have fine careers in science, medicine, biotech, teaching, publishing and law. Please see our lab website:
Invited Lectures and Seminars:
Department of Biology, Princeton University, March 1978
Department of Physiology, Yale University, School of Medicine, May 1978
Department of Biology, University of California, San Diego, August 1978
Department of Neurobiology, Stanford University Medical School, August 1978
Neurobiology Summer Course, Woods Hole, 1978
Department of Physiology, University of California, San Francisco, August 1978
Department of Neurology, Harvard Medical School, January 1979
Cold Spring Harbor Summer Course on “The Synapse”, July 1980
Department of Pharmacology, Tokyo Dental and Medical School, August 1980
Division of Biology, California Institute of Technology, October 1980
Department of Physiology and Anatomy, University of California, Berkeley, May 1982
Department of Biology, Massachusetts Institute of Technology, June 1982
Society for Neuroscience Short Course “Strategies for Studying the roles of peptides in neuronal functions”, Minneapolis, October 1982
Department of Neuroscience, Washington University, St. Louis, January 1983
Cold Spring Harbor Summer Course on “Cellular and Molecular Neurobiology, July 1983
Division of Biology, California Institute of Technology, January 1984
Department of Pharmacology, Tokyo Dental and Medical School, September 1984
University of California, Berkeley, 1986
Department of Neurobiology, Stanford University, April 1986
Department of Biology, Institute of Molecular Biology, UCLA, 1987
Spencer lecture, Columbia University, October 1988
Division of Biology, California Institute of Technology, January 1989
Developmental Biology, University of California, Irvine, January 1989
Department of Biology, Stanford University, January 1989
International Summer School on Molecular Biology of Differentiation, Berlin, July 1989
Woods Hole Neurobiology Course, July 1989
Woods Hole Neurobiology Seminar, July 1989
Department of Cell Biology, Yale University, October 1989
Department of Biophysics, Kyoto University, Kyoto, Japan, March 1990
Distinguished Lecture Series, USC, Dec. 1991
Department of Biology, UC San Diego, Dec. 1991
Department of Biochemistry and Molecular Biology, Harvard University, Dec. 1991
University Lecture, The Rockefeller University, October 1992
Fred Hutchinson Cancer Institute, Seattle, May 1993
Department of Biology, Stanford University, December 1993
Department of Biology, University of Virginia, May 1994
Department of Cell Biology, Harvard Medical School, October 1994
Department of Developmental Biology, Stanford University, March 1995
Department of Molecular Biology, Institut Pasteur, Paris, France, October 1995
Max Planck Institute, Frankfurt, Germany, October 1995
Department of Molecular and Cell Biology, Merck lecture series, UC Berkeley, April 1997
Skirball Institute of Molecular Medicine, NYU Medical Center, April 1997
Cold Spring Harbor “Developmental Neurobiology” course, June 1997
Karolinska Institute “Neuron” Course, Stockholm, Sweden, November 1997
Osaka University Medical School, Osaka, Japan, December 1997
Distinguished Lecture in Cell Biology, Baylor University Medical School, March 1998
Department of Neuroscience, Johns Hopkins University Medical School, March 1998
Neurobiology Seminar, California Institute of Technology, April 1998
University Lecture, University of Texas Southwestern Medical School, May 1998
Department of Cell Biology, Duke University Medical School, May 1998
Neurobiology Seminar, Yale University Medical School, May 1998
EMBL, Heidelberg, Germany, May 1999
Department of Molecular, Cellular and Developmental Biology, University of Colorado at Boulder, January 2000
Institute of Molecular Biology, Academia Sinica, Taipei, Taiwan, January 2000
Chiron, Emeryville, CA, April 2000
Department of Biology, Stanford University, October 2000
Cold Spring Harbor, “Developmental Neurobiology” course, June 2001
Laboratory of Molecular Biology, MRC, Cambridge, UK, September 2001
Department of Molecular Biology, Princeton University, December 2002
Cold Spring Harbor, “Developmental Neurobiology” Course, June 2003
Developmental Biology Program, Sloan Kettering Institute, New York, November 2003
Department of Molecular and Cellular Physiology, Stanford University, May 2004
National Institute of Genetics, Mishima, Japan, December 2004
RIKEN Center of Developmental Biology, Kobe, Japan, December 2004
Department of Molecular and Cell Biology, UC Berkeley, Feb 2005
Broad Institute, MIT, February 2005
Cold Spring Harbor Laboratory, February 2005
Distinguished Speaker in the Developmental Biology Program at the University of Toronto, May 2005
Skirball Institute of Molecular Medicine, NYU Medical Center, May 2005
Children’s Hospital, Harvard Medical School, May 2006
Max Planck Institute, Munich, Germany, May 2006
Kyoto University, Kyoto, Japan, June 2006
Department of Neurobiology, Yale University, March 2008
Department of Pathology, Harvard Medical School, March 2009
Perspective in Neuroscience Lecture Series, UC Davis, April 2009
Edward. M. Scolnick Prize in Neuroscience Lecture, Massachusetts Institute of Technology, May 2010
Invited Speaker in Symposium or Workshop:
Neuroscience Research Program “Neurogenetics” Workshop, Boston, November 1977
International Titisee Conference on “Membrane Channels”, Titisee, West Germany, March 1980
XVI International Congress of Entomology Symposium on “Developmental and Molecular Biology of Insects”, Kyoto, Japan, August 1980
Winter Conference on Brain Research Panel “Neuronal Mechanisms of Peptide Action-Intracellular Studies”, Keystone, Colorado, January 1981
Ciba Foundation Symposium 88 “Neurochemical Pharmacology of Insects”, London, England, July 1981
9th Meeting of the International Neurobiology Society “Molecular and Cellular Interactions Underlying Higher Brain Function”, Val de Loire, France, September 1981
66th Annual Meeting of the FASEB, New Orleans, LA, April 1982. Symposium “Coexistence of neuromodulators: biochemical and pharmacological consequences”.
12th Society for Neuroscience Annual Meeting, Minneapolis, MN, November 1982. Symposium on “The Function of Multi Transmitters in Neurons”.
Cold Spring Harbor 48th Symposium on “Molecular Neurobiology” June 1983
International Symposium on Neuropeptides, Montpellier, France, September, 1983
UCLA Symposium on Molecular Neurobiology, Keystone, Colorado, April 1984
9th International Symposium on Neurosecretion, Japan, September 1984
Cajal Conference on Neurobiology, Madrid, Spain, September 1984
“Coexistence of Neuronal Messengers” Symposium, Stockholm, Sweden, June 1985
“Mechanisms of Secretion and Action of Neurotransmitters and Neuromodulators in Central and Peripheral Synapse”, Jerusalem, Israel, October 1985
EMBO Workshop on “Molecular and Developmental Biology of Drosophila”, Crete, June 1986
HHMI meeting on “Developmental Neurobiology”, Miami, Florida, February 1987
Southern California Drosophila Meeting, UCLA, 1987
Gordon Conference, “Developmental Biology” New Hampshire, July 1987
17th Society of Neuroscience Annual Meeting “Molecular Genetic Analysis of Neuronal Development” Symposium, New Orleans, November 1987
1st NIMH Conference on “Molecular Neurobiology, Santa Barbara, California, May 1988
Society of Developmental Biology 47th Symposium, “The Assembly of the Nervous System” Connecticut, June 1988
Winter Conference of Immunologists, “Development of the Nervous System” Symposium, Asilomar, California, January 1989
Society of Cell Biology and Society of Molecular Biology Joint Annual Meeting, Symposium, San Francisco, January 1989
Miami Biotechnology Winter Symposium, “Molecular Neurobiology”, March 1989
EMBO Workshop on Neurogenesis, Simonswald, West Germany, April 1989
Max Planck Society “Drosophila embryogenesis” symposium, Schloss Ringberg, Tegernsee, West Germany, January 1990
International symposium on pharmacology and drug development based on new biology, Tokyo and Kyoto, Japan, March 1990
Cold Spring Harbor 55th Symposium, “The Brain”, May 1990
Gordon Conference, “Biological Regulatory Mechanisms”, New Hampshire, June 1990
SCBA 3rd International Symposium “Molecular Biology”, Hong Kong, June 1990
NIH Zebrafish Workshop, Eugene, Oregon, Sept. 1990
Fundacion Juan March Workshop on Neural Development in Drosophila, El Palmar, Spain, October 1990
HHMI Workshop on Developmental Neurobiology, Bethesda, Maryland, March 1991
Seymour Benzer Symposium, Cal Tech, Oct. 1991
31st Society of Cell Biology Annual Meeting, “Neural Induction” Symposium, Boston, Massachusetts, Dec. 1991
Gordon Conference “Molecular Genetics”, Rhode Island, July 1992
5th International Congress of Cell Biology, “Early Neurogenesis” Symposium, Madrid, Spain, July 1992
Bambury Workshop on “Constructing Organisms”, Cold Spring Harbor, November 1992
SCBA 5th International Symposium, Keynote Speaker, Baltimore, June 1993
12th International Congress of Developmental Biologists, Vienna Austria, August 1993
National Institute of Child Health and Human Development Workshop on “The Neuronal Phenotype” Corsica France, August 1993
Fundacion Juan March/EMBO Workshop on “Cellular Interactions in the Early Development of the Nervous System of Drosophila” Madrid, Spain, April 1994
“Molecular Neurobiology” Symposium. Uppsala, Sweden, August 1994
Gordon Conference “Developmental Biology”, New Hampshire, June 1995
Eighth IIGB Meeting “Evolution and Development”, Capri, Italy, October 1995
Keystone Symposia “Cell Polarity” Lake Tahoe, California, February 1996
HHMI “Neural Development” Workshop, Chevy Chase, Maryland, February 1996
Keystone Symposia “Signaling in Neuronal Development, Differentiation,” Taos, New Mexico, March 1996
“Molecular Biology: The Next Decade” Symposium, Institute of Molecular Biology, Academia Sinica, Taipai, Taiwan, May 1996
55th Society of Developmental Biology Annual Meeting “Localization and Function of Cytoplasmic Determinants” Symposium, Nashville, Tennessee, May 1996
Gordon Conference “Neural Development”, Newport, Rhode Island, June 1996
Eighth Annual Mahajani Symposium on Molecular Medicine, La Jolla, California, September 1996
1st International Symposium on Molecular Control of Organogenesis, Ann Arbor, Michigan, October, 1996
26th Annual Meeting of the Society for Neuroscience, “Cell Cycle Regulation and CNS Development” Symposium, Washington, D.C., November 1996
Howard Hughes Medical Institute Workshop “Germ Line Development,” Chevy Chase, Maryland, December 1996
Cold Spring Harbor 62nd symposium, “Pattern Formation during Development,” May 1997
Gordon Conference “Developmental Biology,” New Hampshire, June 1997
17th International Congress of Biochemistry and Molecular Biology, “Cell Fate Determination in Development” symposium, San Francisco, California, August 1997
4th International Kyoto Life Science Symposium, “Development and Organization of Complex Multicellular Systems,” Kyoto, Japan, November 1997
Keio University International Symposia for Life Science and Medicine, “Neuroscience: Frontier of Neural Development” symposium, Tokyo, Japan, December 1997
Annual Meeting of American Society for Biochemistry and Molecular Biology, “Signaling Molecules in Development” Symposium, Washington, D.C., May 1998
Nobel Symposium “Assembly of the Nervous System”, Stockholm, Sweden, June 1998
EMBO Workshop on “Molecular and Developmental Biology of Drosophila,” Crete, July 1998
Gordon Conference, “Molecular Genetics,” Rhode Island, July 1998
Banbury Workshop on “Stem Cell,” Cold Spring Harbor, NY, February 1999
The 10th IMP Spring Conference on “The Cell Biology of Cell Division,” Vienna, Austria, May 1999
Inauguration Symposium of Shanghai Institute of Neuroscience, Chinese Academy of Sciences, Shanghai, China, November 1999
Neuroscience Symposium, Xian, China, November 1999
Keystone Symposia, “Stem Cells, Asymmetric Cell Division and Cell Fate,” Keystone, CO, January 2000.
Eighth Symposium on Recent Advances in Cellular and Molecular Biology. Chinese Society of Cell and Molecular Biology, Keynote Lecture, Kenting, Taiwan, January 2000
Keystone Symposia, “Genetic Bases of Brain Development and Dysfunction,” Taos, New Mexico, March 2000
EMBO Workshop in “Molecular and Developmental Biology of Drosophila”, Crete, June 2000.
“Recent Advances in Biomedical Sciences.” Symposium by new members of Academia Sinica, Academia Sinica, Taipei, Taiwan, July 2000
30th Annual meeting of the Society for Neuroscience, “On Form and Function: Molecular Mechanisms of Synapse Development” Symposium, New Orleans, November 2000
14th International Congress on Developmental Biology, Kyoto, Japan, July 2001
Medical Research Council, King’s College, London, Inaugural conference on “The Developing Brain” at Guy’s Hospital, London, UK, September 2001
Keystone Symposia “Stem Cells, Origins, Fates, and Functions” Keystone, CO, March 2002
Gordon Conference “Molecular and Cellular Neurobiology, “ Hong Kong, June 2002
The 2nd Wu Ta You Science Camp, Taiwan, August 2002
62nd Society of Developmental Biology Annual Meeting “From Neuron to Brain” Symposium, Boston, MA, July 2003
“Cell Biology of the Neuron” Neuron 15th Anniversary Meeting, New Orleans, LA, November 2003
Society for Neuroscience 33rd Annual Meeting “Dendrite Development: Morphogenesis, Targeting and Plasticity” Symposium, New Orleans, LA, November 2003
Keystone Symposia “Stem Cells” Keystone, CO, January 2004
SCBA 10th International Symposium, Keynote Speaker, Beijing, July 2004
Gordon Conference “Neural Development”, Newport, Rhode Island, August 2004
Molecular Biology Society of Japan Symposium, Kobe, Japan, December 2004
Autism Think Tank, Columbia University, New York, February 2005
Keystone Symposia "Cell Polarity and Asymmetric Cell Divisions", Keynote Speaker, Coeur d'Alene, Idaho, March 2005
46th Annual Drosophila Research Conference, Plenary Lecture, San Diego, March 2005
Keystone Symposia "Axonal Connections: Molecular Cues for Development and Regeneration" Breckenridge, CO, April 2005
The 4th Wu Ta You Science Camp, Taiwan, August 2005
15th International Congress on Developmental Biology, Plenary Lecture, Sydney, Australia, September 2005
EMBO Workshop, Ascona, Switzerland, September 2005
University of Utah Neuroscience Snowbird Symposium, Keynote Speaker, Snowbird, Utah, October 2005
UCSD Neuroscience Symposium on the Assembly of Neural Circuits, La Jolla, CA, January 2006
International Symposium on Epithelia Organization and Organ Development. Keynote speaker, Max Delbrück Center, Berlin, Germany, May 2006.
Gordon Conference “Molecular and Cellular Neurobiology,” Hong Kong, June 2006
Osaka-NAIST Joint COE Symposium “Cells to Organisms”, Nara, Japan, June 2006
20th IUBMB International Congress of Biochemistry and Molecular Biology “Neuronal Polarity” Symposium, Kyoto, Japan, June 2006
SCBA 11th International Symposium, Keynote Speaker, San Francisco, July 2006
Santa Cruz Developmental Biology Meeting, Santa Cruz, CA, August 2006
Cold Spring Harbor Meeting “Axon Guidance, Synaptogenesis and Neural Plasticity, ” Cold Spring Harbor Lab, NY September 2006
Society for Neuroscience 36th Annual Meeting “Neuronal Polarity” Symposium, Atlanta, GA, October 2006
UCSF/Karolinska Stem Cell Symposium, UCSF, San Francisco, CA, January 2007
Gordon Conference “Dendrites: Molecules, Structure and Function.” Ventura, CA, March 2007
2007 Asian Science Camp, Taipei, Taiwan, August 2007
Bay Area Neuroscience Gathering, Keynote speaker, UCSF, January 2008
UCSF Cancer Center Symposium “Stem Cells and Cancer”, UCSF, May 2008
17th Biennial Meeting of the International Society for Developmental Neuroscience, Plenary Lecture, Asilomar, CA, June 2008
UCSF Center for Neurobiology and Psychiatry Symposium “Understanding Autism: lessons from genetics and rules of brain development”, UCSF, June 2008
Gordon Conference “Neural Development”, Newport, Rhode Island, August 2008
Janelia Conference, “Behavioral Neurogenetics of Drosophila Larva” meeting, JFRC, HHMI, October 2008
San Francisco-Japan Joint Meeting on Vertebrate Organogenesis, UCSF, November 2008