CURRICULUM VITAE
Name / Dr.Sachidananda Adiga M.N., MD(Pharmacology)Designation / Associate Professor, IGMC, Puducherry since March 2010
Qualification:
MBBS: Karnataka Medical College, Hubli.1996
MD: Kasturba Medical College Mangalore, 2001
Teaching Experience:-
Tutor in Pharmacology: Kasturba Medical College, Mangalore 1998-2001
Assistant Professor (Pharmacology): Kasturba Medical College, Manipal
12/10/2001- 11/10/2006
Associate Professor (Pharmacology): Kasturba Medical College, Manipal
12/10/2006 to 27-03-2010
Associate Professor ((Pharmacology): IGMC & RI, Pondicherry
29-03-2010 to till today
Involved in undergraduates and postgraduate students of following courses (MBBS, MD, M Sc, BDS, Biotechnology, Allied health science specialties and guided postgraduates in dissertation work )
RESEARCH EXPERIENCE:
Clinical trials: Worked as study coordinator / sub investigator in Phase II and Phase III multicentric RCT .
1. Efficacy and Tolerability of Dianex in Type 2 Diabetes.
2. Efficacy and Tolerability of Glucosamine- Chondroitin Sulphate –Methyl Sulfonyl Methane in Ostearthritis of Knee in Indian Patients.
3. Efficacy and tolerability of Trandolapril versus Enalapril in mild to moderate hypertension- A Randomized Double Blind Multicentric Comparative Clinical Trial- A Randomized Double Blind Multicentric Comparative Clinical Trial.
4. Efficacy, safety and tolerability of FK463 versus liposomal Amphoterecin B in Candidemia- A Randomized Double Blind Multicentric Comparative Clinical Trial.
5. Efficacy and tolerability of Caspofungin versus Micafungin in candidemia and invasive candidiasis- A Randomized Double Blind Multicentric Comparative Clinical Trial.
6. Efficacy and tolerability of Oxcarbazepine CR versus Oxcarbazepine IR preparation in simple and partial complex seizures- A Randomized Double Blind Multicentric Comparative Clinical Trial.
7. Efficacy and tolerability of Aliskerin alone or Aliskerin with atenolol in mild hypertension – A Phase III Double blind Randomized Dose escalation Multicentre clinical trial.
8. Efficacy and safety of WSA (Water Soluble Azole) – Isovoconazole versus Voriconozole in aspergillosis- A Randomized Double Blind Multicentric Comparative Clinical Trial.
9. Efficacy and safety of Abatacept in Crohn’s disease and ulcerative colitis- A Randomized Double Blind Placebo control Multicentric Comparative Clinical Trial.
10. Efficacy and safety of Golimumab in ulcerative colitis- A Randomized Double Blind Placebo control Multicentric Comparative Clinical Trial.
11. Efficacy and safety of doripenam in hospital acquired pneumonia – An open label Phase II Multicentric Clinical Trial
12. Efficacy and Safety of Enoxaparin versus placebo in addition to graduated elastic stockings in assessing overall mortality in acutely ill medical patients- A Double blind Phase III multicentric clinical trial.
13. A randomized double blind, multicenter study to evaluate the efficacy of Apixaban in the treatment of deep vein thrombosis.
Clinical Research:-
1. Pattern of antimicrobial agents use in hospital deliveries: A prospective comparative study.
2. Safety and radiosensitizing efficacy of Sanazole (AK2123) in oropharyngeal cancers: Randomized controlled double blind clinical trial.
3. Evaluation of fixed dose combination drugs in tertiary care hospital.
4. Evaluation of efficacy and tolerability of adjuvant chemotherapeutic regimens used in colorectal carcinoma in a tertiary care hospital – A retrospective study.
5. Evaluation of efficacy and tolerability of adjuvant chemotherapeutic regimens used in breast cancer in a tertiary care hospital – A retrospective study.
6. Evaluation of fixed dose combination drugs in tertiary care hospital.
Basic research:
1. Wound healing property of various extracts of Areca catechu on different animal wound models.
2. Wound healing property of alcoholic extract of Kaempferia galanga root in dexamethasone suppressed animal wound model.
3. Evaluation of effect of water stored in copper vessels on experimentally induced
gastric ulcer in rats.
4. Percutaneous absorption and comparative irritability of clobetazole propionate in presence of various zinc salts in male wistar rats.
5. Effect of betamethasone valerate biopolymer on skin inflammatory models in albino mice and wistar rats.
6. Comparative effect of sodium fusidate,framycetin and calcium mupirocin on experimentally induced burn wound healing.
Research Interests:-
1. Innovative approaches in medical education.
2. Pharmacoviogilance
Publications:
1. Sudha V, Prabhu Mukhyaprana, Shashikiran U, Adiga Sachidananda,
Sharath Rao, K Laxminarayana Bairy, Shalini Adiga and B. Jayaprakash.
Efficacy and Tolerability of Glucosamine- Chondroitin Sulphate –Methyl
Sulfonyl Methane in Ostearthritis of Knee in Indian Patients. IJPT 2004; 3: 61-65.
2. Sudha V, Bairy KL, Adiga Sachidananda, Shashikiran U, Shalini Adiga. Efficacy and Tolerability of Dianex in Type 2 Diabetes. Mellitus patiens –A Randomized Open Label Non Comparative study. Med J Malaysia 2005; Vol 60 (2): 204-211 1-7.
3. KL Bairy,SB Ganesh,MS Adiga &A Shalini.Impaired wound healing due to Cyclophosphomide (CLP) alleviated by supplemental Ginkgo biloba(GB).Journal of Natural Remedies; 2006 Vol 6/1: 31-34.
4. Shanbhag TV, Sharma Chandrakala,Adiga Sachidananda,Bairy Kurady Laxminarayana ,Shenoy Smita, Shenoy Ganesh, Bairy KL. Wound healing activity of alcoholic extracts of K. galanga extracts in Wistar rats. Indian J Physiol Pharmacol 2006;50(4) : 384-390
5. Pinakini S, Sudha V, Adiga Sachidananda, Naidu MUR, Usha Rani P, Dayasagar Rao, Bairy KL,Nair Sreekumaran,Jayaprakash B, Shashikiran U and Prabhu Mukhyaprana .Efficacy and tolerability of Trandolapril in mild to moderate Hypertension- A Double Blind Comparative Multicentre Clinical Trial with Enalapril in Indian Population.Indian J Physiol Pharmacol 2006; 50 (4): 421-426
6. Ullal SD, Shenoy KK, Pai MRSM, Chowta MN, Adiga SMN, Dinesh M, Kamath A, Kotian MS, Pai DK. Safety and radiosensitizinf efficacy of Sanazole (AK2123) in oropharyngeal cancers: Randomized controlled double blind clinical trial. Indian Journal of Cancer 2006; 43(4) 151-155.
7. Shamina Azeez, Senthil Amudhan, Adiga Sachidananda Adiga, Rao Namita,
Rao Nirmala, Laxminarayana L. Udupa.Wound Healing Profile of Areca Catechu
Extracts on different wound models in Wistar Rats. Kuwait Medical Journal
2007; 39(1) : 48-52
8. Ashwin KA, Bairy KL, Sudha Vidyasagar, Muralidhar Varma, Prashanth CK, Sachidananda A. Aspirin Resistance. India J Physiol Pharmacol 2007; 51(2): 109-117.
9. Bairy KL, Thirumalaikolundusubramanian P, Sivagnanam G, Saraswathi S, Sachidananda A, Shalini A. Bullying among trainee doctors in Southern India: A questionnaire study. Journal of Postgraduate Med 2007; 53(2) 87-90.
10. Usha S Adiga, Sachidananda Adiga .Antioxidant Activity in old age Biomedical Research 2008; 19(3):191-193.
11. Eesha BR, Shanbhag TV, Adiga Sachidananda Shenoy Smitha. Evaluation of fixed dose combination drugs in tertiary care hospital. Biomedical Research 2009; 20 (3) : 106-109.
12. Usha Adiga, Sachidananda Adiga. Antioxidant activity in normal pregnancy. Online journal of health Sciences.2009; 4
13. Chogtu Bharti, Adiga Sachidananda, Prabhu Mukhyaprana, Bairy KL. Evaluation of efficacy and toxicity of different treatment regimens in plasmodium falciparum malaria.JPRHC July 2009; 1(1): 134-140.
14. Adiga MNS, Alwar MC, Pai MRSM, Adiga US. Pattern of antimicrobial agents use in hospital deliveries: A prospective comparative study. Online journal of health Sciences, 2009; 8(4) :10
15. Adiga Sachidananda, Adiga Usha. PBL –A learning method of pharmacology in medical school Biomedical Research 2010 (1).
16. Prashant BM, Praful BD, Swapnil JD, Kranti BT, Shriram MP, Adiga MNS, Krishnamurthy B, Nayanabhirama U and Bairy KL. High Performance Liquid Chromatographic Method for Determination of Clobetasol in Rat Plasma and its Application to Skin Penetration JBABM 2010; 2(1): 01-07.
17. Adiga Sachidananda, Meena Kumari, Bairy KL, Mohan A, Vadhiraj BM, Vidyasagar MS. The Effect of using combination chemotherapy in colorectal cancer in India: a single institute survey. Pharmacologyonline, 2010; 1: 518-529.
18. Adiga Sachidananda, Adiga Usha. Comparative study of different modalities of assessment in self directed learning. Pharmacologyonline, 2010; 1: 245-251 (newsletter).
19. Usha Adiga, Sachidananda Adiga, Dyslipedimia in pregnancy induced hypertension. J Global Pharm Therapeutics; 2010; 2 (5): 69-72.
20. Sachidananda Adiga, Jennie Tan Usha Adiga. Health care cost incurred by patients of Type 2 diabetes in a tertiary care hospital in coastal Karnataka. J Global Pharm Therapeutics. 2010; 2(6): 8-12.
21. Sachidananda Adiga, Jennie Tan, Usha Adiga. Glycemic control and complications of diabetes mellitus. J Global Pharm Therapeutics. 2010; 2(7): 60-63.
22. Satish Kumar MC, Sachidananda Adiga, Avin D’Souza, Purnima Sirigiri, Deepa Ayappa, Veena Nayak, Bharti Chogtu, KL. Bairy. Effect of betamethasone valerate biopolymer on skin inflammatory models in albino mice and wistar rats” Int J Pharm
Sci Bio. 2010; 4(2): 173-175.
23. Vasudha Devi, Reem R Abraham, Sachidananda Adiga, Ramnarayan K. Mentored student project for inculcating research skills. Medical Education, 2010; 44(5): 496
24. KL. Bairy, Veena Nayak, Satish Kumar MC, Sachidananda Adiga, Avinash Holla, Pawan Kumar, Rajesh CS, Chandrashekhar BR, Bharti Chogtu.Comparative effect of Sodium fusidate, Framycetin and Calcium mupirocin on experimentally induced burn wound healing.Int J Pharm Sci Bio 2010;1(2): 100-102
Workshops & CME Attended:
1. National Workshop on Clinical Pharmacology organized by PGIMER Chandigarh, 2002, Feb
2. 3rd ICMR training course on clinical pharmacology of Traditional Medicine, organized by TNMC &BYL Nair Hospital Mumbai, 2002.
3. CME on Recent trends in Pharmacogenomics held in KMC Manipal, Sep 2002.
4. Workshop on “Clinical Trial –Design and Analysis” conducted by Community Medicine Department, KMC Manipal, Dec 2002.
5. CME on Biotechnogy &Genetics in Medicine held in KMC Manipal, Nov 2003.
6. CME on “Laboratory Medicine: Towards more effective practices” by Melaka Manipal Medical College, International Centre for Health Sciences in Aug 2004.
7. CME on “Path physiology of Neurodegenerative Diseases” held in NIMHANS Bangalore on Dec 2004.
8. Workshop on Orientation to “Clinical Trials and GCP Guidelines” conducted by KMC AcuNova in KMC Hospital Mangalore ON June 2005.
9. Workshop on E-learning held in Manipal on June 2005.
10. Workshop on Bioethics and role of human subjects in clinical trials organized by ICMR, New Delhi on 13-08-05 in Manipal.
11. Attended workshop on “Research Methodology and Biostatistics” in Manipal on 18-19, September 2008.Awareness programme on
12. Attended workshop on “Introduction to Evidence Informed Health Care” in Manipal on 5-12-2008.
13. Various investigator’s meetings of clinical trial held in Singapore, Malaysia,
London, Delhi, Mumbai, Bangalore, Hyderabad during 2002-2008.
14. Workshop on Pharmacovigilance held on 30-31, March at JIPMER, Pondicherry,2011
15. Awareness programme on Pharmacovigilance programme at JIPMER On Jan 2011.
16. CME on Antimicrobial Resistance held on October 26th ,2010 at MGMC & RI, Pondicherry
Papers presented in Conferences:
1. Drug utilization pattern of antimicrobial agents in hospital deliveries at Southern Regional Conference of Pharmacology held at Trivandrum, India in Aug 2001.
2. Efficacy and tolerability of Dianex in Type 2 Diabetes in Southern Regional Conference of Pharmacological Society, Mangalore, India, in Aug 2002.
3. Critical evaluation of antimicrobial agent utilization in hospital deliveries in the 35th Annual Conference of Indian Pharmacological Society at Gwalior, India in Nov 2002.
4. Wound healing profile of Areca catechu extracts on different wound models in male Wistar rats at Golden APPICON 2004 NIMHANS , Bangalore, India,2004.
5. Prescription auditing of adjuvant chemotherapeutic agents in colorectal carcinoma in Kasturba Hospital Manipal at Chennai, India –Annual conference of Indian Pharmacological Society, 2005.
6. Attended annual conference of 38th Association of Clinical Biochemists of India, 2005 at Patna, India.
7. Attended and presented a poster on “ Changing pattern of learning method of pharmacology in Medical school” in Annual Conference of Indian Pharmacological Society in Chandigarh, 2007
8. Attended and presented a poster on “Comparative study of different modalities of assessment in self directed learning process in pharmacology” in Annual APPICON, in Mangalore, Dec 2008.
9. Attended International Conference on Emergency Relief Activities in SAARC Countries organized by AMDA India Chapter on 13-14th, Feb 2008 in Manipal.
10. Presented a paper on Students perception on different components of problem based learning in pharmacology in a medical school at Kaula Lumpur on April 1-3, 2009.
11. Glycolic control and complications of diabetes mellitus in ACBICON at Cochin on 5-7 Nov , 2009
12. Resource person for the workshop conducted by Department of Community Medicine , IGMC &RI, on Diabetes Mellitus for medical officers of Puducherry in 2011.
Guest Lecture:
1. Delivered a guest lecture on Hypertension –“How to live with it” at CPCRI (regional) vital Karnataka on July 16, 2004.
2. Delivered a speech on Randomizing, Blinding, Drug preparation and dispensing according ICH-GCP Guidelines in a double blind clinical trial at a Workshop organized by ACUNOVA. KMC Manipal in Manipal October 2005.
3. Delivered guest lecture on “Role of Biomarkers in the management of breast cancer” in MCOPS, Manipal on 23-08-2008 as a part of QIP –Program.
4. Delivered guest lecture on “Recent advances in the management of Inflammatory Bowel Disease” in MCOPS, Manipal on 05-02-2009 as a part of QIP –Program.
5. Delivered guest lecture on “Recent advances in the Neurotransmission” in MCOPS, Manipal on 23-06-2009 as a part of QIP –Program.
6. Delivered a guest lecture on “What an ethics committee will ask during the submission of research protocol” in the workshop held on “Ethics in clinical research” at Manipal University on 06-02-2010 at Manipal.
7. Delivered a guest lecture on SLOT- A novel method in teaching pharmacology for medical undergraduates in IPS Conference- 2011, Pondicherry Chapter at JIPMER
Trainer:
1. Resource person in training programme of International Qualifying Examination (UK) for graduates and practicing dentists of India at Manipal since Feb 2005.
2. Resource person for USMLE tutorial Classes organized by Manipal Universal Learning.
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