Data S1. MAGI Proteins and Their Binding Partners. All Three MAGI Family Members Have

Data S1. MAGI Proteins and Their Binding Partners. All Three MAGI Family Members Have

Data S1. MAGI proteins and their binding partners. All three MAGI family members have the same domain structure, shown in the yellow column on the left. The boxes to the right of this show, for each of the MAGIs, which proteins bind to which of the MAGI domains. Boxes spanning more than one domain correspond to proteins whose binding site in MAGI has not been determined precisely but is known to lie somewhere within the indicated region.

MAGI-1
(synonyms BAIAP1, BAP1, AIP3, WWP3, TNRC19) / MAGI-2
(synonyms AIP1, ACVRIP1, Acvrinp-1, ARIP1, S-SCAM) / MAGI-3
(synonym SLIPR)
Domain / Binding partner(s)
PDZ0 / RapGEP [1]
GuK / SAPAP [2]
WW1 / atrophin-1 [3] / atrophin-1 [3]
WW2 / synaptopodin [4] / SMAD3 [5]
PDZ1 / ß1-adrenergic receptor [6]
mNET-1 [7]
HPV16/18 E6 protein [8, 9],
adenovirus-9 E4 protein [10]
JAM4 [11] / MuSK [12]
ASIC3 [13] / ß1-adrenergic receptor [6]
neuroligin [2]
GDP-GTP exchange factor nRAP-GEP [14]
HPV16/18 E6 protein [8] / KIF1B [15] / HPV16/18 E6 protein [8]
Ltap [16]
Frizzled-4 [16]
Frizzled-7 [16]
PDZ2 / PTEN [17-20] / RPTPß [21] / PTEN [22] / RPTPß [21]
PDZ3 / adenovirus-9 E4 protein [10]
PDZ4 / BAI-1 [23]
JAM4 [11]
Delta1/DeltaD/DeltaC [this paper] / Delta1 [32]
Delta1/DeltaD/DeltaC [this paper] / MAGUIN-1 [24] / Delta1/DeltaD/
DeltaC [this paper]
BAI-1 [22]
PDZ5 / alpha-actinin-4 [4],
megalin [25],
ß-catenin [26] / delta2 glutamate receptor [27]
activin receptor IIA [5]
tamalin [28]
NMDA receptors [2, 29]
ß-catenin [30]
delta-catenin/NPRAP [31] / NMDA receptor 2B [22]

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[1] Mino et al. (2000).

[2] Hirao et al. (1998).

[3] Wood et al. (1998).

[4] Patrie et al. (2002).

[5] Shoji et al. (2000).

[6] Xu et al. (2001).

[7] Dobrosotskaya (2001).

[8] Thomas et al. (2002).

[9] Thomas et al. (2001).

[10] Glaunsinger et al. (2000).

[11] Hirabayashi et al. (2003).

[12] Strochlic et al. (2001).

[13] Hruska-Hageman et al. (2004).

[14] Ohtsuka et al. (1999).

[15] Mok et al. (2002).

[16] Yao et al. (2004).

[17] Wu et al. (2000a).

[18] Vazquez et al. (2001).

[19] Torres et al. (2003).

[20] Tolkacheva et al. (2001).

[21] Adamsky et al. (2003).

[22] Wu et al. (2000b).

[23] Shiratsuchi et al. (1998).

[24] Yao et al. (1999).

[25] Patrie et al. (2001).

[26] Dobrosotskaya and James (2000).

[27] Yap et al. (2003).

[28] Kitano et al. (2003).

[29] Hirao et al. (2000a; 2000b).

[30] Nishimura et al. (2002).

[31] Ide et al. (1999).

[32] Pfister et al. (2003)

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