AAPS Webinar Proposal Submission Form

Instructions:

Please note that forms will be immediately rejected unless all requested information is complete.

1. Please complete this form in its entirety by placing your cursor in the gray boxes and typing the information.

2. There is an example of an appropriately completed form on pages 4-6 for your reference.

3. Save the completed form on your desktop and then submit by emailing as an attachment to the addresses shown at the bottom of the form.

This form will be submitted to the AAPS eLearning Committee for review and their feedback will be sent back to you promptly.

Your AAPS Section/FG (if any):
Proposed Webinar Title:
Primary Webinar Organizer (that is probably you):
Name:
Company:
Phone:
Email:
Webinar Presenter #1:
Name:
Company:
Phone:
Email:
Webinar Presenter #2 (optional):
Name:
Company:
Phone:
Email:
Webinar Moderator:
Name:
Company:
Phone:
Email:
Program Description: (175 word minimum)
Learning Objectives: (in bullet point format, outlining the knowledge that will be gained by participants)
Who will benefit most from this webinar?
Please check the gray boxes for all relevant sections, words, and terms applicable to the proposed webinar. The items you check will be used to index your event listing on the AAPS website.
Analysis and Pharmaceutical Quality Section / Biotechnology Section
Clinical Pharmacology and Translational
Research Section / Drug Design and Discovery Section
Formulation Design and Development
Section / Manufacturing Science and Engineering
Section
Physical Pharmacy and Biopharmaceutics
Section / Pharmacokinetics, Pharmacodynamics and
Drug Metabolism Section
Regulatory Sciences Section
ADME / Forced Degradation
Analytical Method Development / Formulation
Animal Welfare / Formulation Design and Development
Bioequivalence / Freezing and Drying Technologies
Biopharmaceutics / Guidance on Drug Interactions
Biopharmaceutics Classification System / Hot Melt Extrusion
Biotechnology / HPLC
Chromatography / Human Cytochromes P450
Clinical Trials / ICH Q8- Q9- Q10
Combination Products / Immunogenicity
Compliance Trends / In Vitro Release and Dissolution Testing
Continuous Process / IND
Delivery / Inhalation and Nasal Technology
Discovery / Manufacturing
Drug Delivery / Mass Spectrometry
Drug Disposition / Modified Release
Drug Manufacturing / Nanotechnology
Drug Transport / NDA
Fluid Drying / Non-Clinical Dose Formulation Analysis
Excipients / PAT
Fluid Drying / Pharmaceutical Manufacturing

Please enter below any other terms NOT listed above that can be used as search terms. Please do NOT include terms or words used in any titles or description of your event.

Enter Keywords:

Please review this proposal with your presenter(s). It will be the basis for the webinar promotion.

Send your presenter and moderator the Webinar Guidelines

Send your presenter the Speaker Release Form

Email completed form to: Meredith Voelkel, Professional Development Manager

All approved webinars are scheduled on a first-come, first-served basis.

EXAMPLE OF AN APPROPRIATE WEBINAR SUBMISSION

Your Section or Focus Group: / Discovery Modeling and Simulation Focus Group and DDDI
Proposed Webinar Title:
In Silico Tools in Preformulation and Formulation Development
Primary Webinar Organizer (that is probably you):
Name: / Jane Smith
Company: / Concordia University Wisconsin
Phone: / 555-555-5555
Email: /
Webinar Presenter #1:
Name: / John White
Company: / Merck & Co., Inc.
Phone: / 555-555-5555
Email: /
Webinar Presenter #2 (optional):
Name: / n/a
Company:
Phone:
Email:
Webinar Moderator:
Name: / Chris Brown
Company: / Genentech, Inc.
Phone: / 555-555-5555
Email: /
Learning Objectives:
·  Understand Predicting and Optimizing Physical Properties
- Prediction of PhysChem properties
- Optimization of properties at the design stage. SPR approaches
- Correlation between physical attributes and ADME properties
·  Discuss Absorption and Formulation Modeling
- Simple absorption models and application for preclinical studies
- Leveraging commercial software packages
·  Explore BCS and BDDCS Predictions
- Predictions of solubility, permeability, and metabolism to forecast regulatory risks
Abstract: (175 word minimum)
The formulation of a drug can impact its route and frequency of administration, its ADME and safety profiles as well as its shelf-life. The preformulation development and characterization of the physicochemical properties of a drug candidate provide the basis for the selection of suitable preclinical or clinical formulations. Properties such as molecular weight, pKa, log D7, solubility and particle size can affect drug absorption and bioperformance. However, most of these properties are commonly experimentally measured to determine a formulation strategy, which requires a significant amount of time and resource investment. Accurate prediction of these properties would preclude the need for experimental assessment. Thorough understanding of the physicochemical properties can then accelerate formulation development, optimize bioperformance, and reduce timelines and risks associated with drug candidate development. In silico approaches have the promise for guiding and enabling rapid formulation selection at an early stage.
This webinar will summarize efforts made around the prediction of physicochemical properties of molecules and modeling of the absorption and bioperformance of drug candidates, and will describe how this information can be used to reduce the risks present in drug development.
Who will benefit most from this webinar?
Industry scientists seeking to gain an understanding of the utility of current in silico modeling approaches and applications towards the characterization and formulation development of new drug candidates. Academic scientists with interests in translation of drug discovery and into preclinical development.
Please check the gray boxes for all relevant sections, words, and terms applicable to the proposed webinar. The items you check will be used to index your event listing on the AAPS website.
Analysis and Pharmaceutical Quality Section / Biotechnology Section
Clinical Pharmacology and Translational
Research Section / X / Drug Design and Discovery Section
X / Formulation Design and Development
Section / Manufacturing Science and Engineering
Section
X / Physical Pharmacy and Biopharmaceutics
Section / Pharmacokinetics, Pharmacodynamics and
Drug Metabolism Section
Regulatory Sciences Section
X / ADME / Forced Degradation
Analytical Method Development / X / Formulation
Animal Welfare / X / Formulation Design and Development
Bioequivalence / Freezing and Drying Technologies
X / Biopharmaceutics / Guidance on Drug Interactions
X / Biopharmaceutics Classification System / Hot Melt Extrusion
Biotechnology / HPLC
Chromatography / Human Cytochromes P450
Clinical Trials / ICH Q8- Q9- Q10
Combination Products / In Vitro Release and Dissolution Testing
Compliance Trends / IND
Continuous Process / Inhalation and Nasal Technology
Delivery / Manufacturing
Discovery / Mass Spectrometry
X / Drug Delivery / Modified Release
Drug Disposition / Nanotechnology
Drug Manufacturing / NDA
Drug Transport / Non-Clinical Dose Formulation Analysis
Fluid Drying / PAT
Excipients / Pharmaceutical Manufacturing
Fluid Drying

Please enter below any other terms NOT listed above that can be used as search terms. Please do NOT include terms or words used in any titles or description of your event.

Enter Keywords: / Preclinical modeling, simulation, computational tools, BCS, BDDCS