www.moleculeralabs.com/moleculera-labs-pandas-and-pans-video/
www.nimh.nih.gov/labs-at-nimh/research-areas/clinics-and-labs/pdnb/web.shtml
www.latitudes.org
www.pandassucks.com
www.nepans.org/symptoms--supports.html
www.iocdf.org/pandas/
www.strepmonster.com
www.cast.org/our-work/about-udl.html#.WPz60kXytdg
Research, Articles & Case Studies
2017
A Double-Blind Randomized Placebo-Controlled Pilot Study of Azithromycin in Youth with Acute-Onset Obsessive-Compulsive Disorder.
Murphy TK1,2,3, Brennan EM1, Johnco C4, Parker-Athill EC1, Miladinovic B5, Storch EA1,2,3,6,7, Lewin AB1,2. (J Child Adolesc Psychopharmaco -2017)
Read Abstract
Vitamin D Deficiency in Obsessive-Compulsive Disorder Patients with Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections: A Case Control Study.
Çelik G1, Taş D2, Tahiroğlu A1, Avci A1, Yüksel B3, Çam P2. (Noro Psikiyatr Ars-2017)
Read Abstract
Improvement of psychiatric symptoms in youth following resolution of sinusitis
Talia Mahony, Douglas Sidell, Hayley Gans, Kayla Brown, Bahare Farhadian, Melissa Gustafson, Janell Sherr, Margo Thienemann, Jennifer Frankovich (International Journal of Pediatric Otorhinolaryngology-2017)
Read Study
2016
The neuropsychological profile of children with basal ganglia encephalitis: a case series.
Pawela C, Brunsdon RK, Williams TA, Porter M, Dale RC, Mohammad SS (Dev Med Child Neurol.-2016)
Abstract
Microglial Dysregulation in OCD, Tourette Syndrome, and PANDAS
Luciana Frick, Christopher Pittenger (Journal of Immunology Research- 2016)
Read Review Article
Randomized, Controlled Trial of Intravenous Immunoglobulin for Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcal Infections
Kyle A. Williams, MD, PhD, Susan E. Swedo, MD, Cristan A. Farmer, PhD, Heidi Grantz, LCSW, Paul J. Grant, MD, Precilla D’Souza, CRNP, Rebecca Hommer, MD, Liliya Katsovich, MA, Robert A. King, MD, James F. Leckman, MD, Phd (Journal of the American Academy of Child & Adolescent Psychiatry – 2016)
Read Article
Rapid Eye Movement Sleep Abnormalities in Children with Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS).
Gaughan T ,Buckley A, Hommer R, Grant P, Williams K, Leckman JF, Swedo SE (J Clin Sleep Med - 2016)
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PANDAS: Baseline Immunoglobulin Levels Predict Achievement of Remission at One Year Following IVIG Therapy
David S. Younger, Phyllis A. Mast, and Denis A. Bouboulis (Journal of Neurology and Neurosurgery, 2016)
Read More at Journal of Neurology and Neurosurgery
Full PDF
Pediatric Autoimmune Disorders Associated with Streptococcal Infections and Tourette's Syndrome in Preclinical Studies
Chiara Spinello, Giovanni Laviola and Simone Macrì (Frontiers in Neuroscience – 2016)
Full Article
Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections (PANDAS)
Graziella Orefici, PhD, Francesco Cardona, MD, Carol J. Cox, PhD, and Madeleine W. Cunningham, PhD. (From the Book: Streptococcus pyogenes
Basic Biology to Clinical Manifestations - University of Oklahoma Health Sciences Center; 2016)
Link to Book Chapter
N-Acetylcysteine in the Treatment of Excoriation Disorder - A Randomized Clinical Trial
Jon E.Grant,JD, MD, MPH; Samuel R.Chamberlain,MD, PhD; Sarah A.Redden,BA; Eric W.Leppink,BA; Brian L.Odlaug,PhD; Suck WonKim,MD (JAMA Psychiatry. 2016 )
Read More on Clinical Trial
2015
Therapeutic Plasma Apheresis as a Treatment for 35 Severely Ill Children and Adolescents with Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections
M. Elizabeth Latimer, Nathan L'Etoile, Jakob Seidlitz, Susan E. Swedo (JCAP-2015) (2015)
Abstract
Use of Intravenous Immunoglobulin in the Treatment of Twelve Youths with Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal infections
Miro Kovacevic, Paul Grant, Susan E. Swedo (JCAP-2015) (2015)
Abstract
Antineuronal Antibodies in a Heterogeneous Group of Youth and Young Adults with Tics and Obsessive-Compulsive Disorder
Carol J. Cox, Amir J. Zuccolo, Erica V. Edwards, Adita Mascaro-Blanco, Kathy Alvarez, Julie Stoner, Kiki Chang, Madeleine W. Cunningham (JCAP-2015) (2015)
Abstract
Cytokine Correlations in Youth with Tic Disorders
E. Carla Parker-Athill, Jared Ehrhart, Jun Tan, Tanya K. Murphy (JCAP-2015) (2015)
Abstract
Clinical Presentation of Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal infections in Research and Community Settings
Susan E. Swedo, Jakob Seidlitz, Miro Kovacevic, M. Elizabeth Latimer, Rebecca Hommer, Lorraine Lougee, Paul Grant (JCAP-2015) (2015)
Abstract
Five Youth with Pediatric Acute-Onset Neuropsychiatric Syndrome of Differing Etiologies
Jennifer Frankovich, Margo Thienemann, Sonal Rana, Kiki Chang (JCAP-2015) (2015)
Abstract
Multidisciplinary Clinic Dedicated to Treating Youth with Pediatric Acute-Onset Neuropsychiatric Syndrome: Presenting Characteristics of the First 47 Consecutive Patients
Jennifer Frankovich, Margo Thienemann, Jennifer Pearlstein, Amber Crable, Kayla Brown, Kiki Chang (JCAP-2015) (2015)
Abstract
Group A Streptococcus intranasal infection promotes CNS infiltration by streptococcal-specific Th17 cells
Thamotharampillai Dileepan, Erica D. Smith, Daniel Knowland, Martin Hsu, Maryann Platt, Peter Bittner-Eddy, Brenda Cohen, Peter Southern, Elizabeth Latimer, Earl Harley Dritan Agalliu. and P. Patrick Cleary (Journal of Clinical Investigation-2015)
Article
Diagnosis Deconstructed: A Recipe for Encephalopathy
Morchi, Ravi MD (Emergency Medicine News-2015)
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PANS consensus conference: Full medical evaluation needed
(The Brown University Child & Adolescent Psychopharmacology Update-2015)
Abstract
Detection of anti-streptococcal, antienolase, and anti-neural antibodies in subjects with early-onset psychiatric disorders.
Nicolini H, López Y, Genis-Mendoza AD, Manrique V, Lopez-Canovas L, Niubo E, Hernández L, Bobes MA, Riverón AM, López-Casamichana M, Flores J, Lanzagorta N, De la Fuente-Sandoval C, Santana D. (Actas Esp Psiquiatr -2015)
Abstract
Waking Up to a Child With Abrupt Personality Changes
Michelle M. Papachrisanthou, DNP, CPNP-PC, Renée L. Davis, DNP, CPNP-PC (Jouranl of Nurse Practitioners-2015)
Abstract
Pediatric Autoimmune Neuropsychiatric Disorder Associated with Streptococcus Immunology: A Pilot Study
Walls A, Cubangbang M, Wang H, Raiji M, Knight J, Steehler M, Latimer E, Harley EH Jr. (Otolaryngol Head Neck Surg.-2015)
Abstract
The Role of Tonsillectomy in the Treatment of Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcal Infections (PANDAS)
DanielDemesh,MD; Jordan M.Virbalas,MD; John P.Bent,MD (JAMA Otolaryngol Head Neck Surg.-2015)
Abstract
Implications for Advanced Practice Nurses When Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcal Infections (PANDAS) Is Suspected: A Qualitative Study
Molly McClelland, PhD, RN, Mary-Margaret Crombez, MEd, Catherine Crombez, BSc, Catherine Wenz, MSN, RN, FNP-BC, Margaret Lisius, MSW, Amanda Mattia, BSN, RN, Suzana Marku, BSN, RN (JPED-2015)
Abstract
Basal ganglia inflammation in children with neuropsychiatric symptoms
Ajay Kumar, Mitchel Williams, Otto Muzik and Harry Chugani (Journal of Nuclear Medicine – 2015)
Abstract
2014
Clinical Evaluation of Youth with Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS): Recommendations from the 2013 PANS Consensus Conference
Kiki Chang, Jennifer Frankovich, Michael Cooperstock, Madeleine W. Cunningham, M. Elizabeth Latimer, Tanya K. Murphy, Mark Pasternack, Margo Thienemann, Kyle Williams, Jolan Walter, Susan E. Swedo, From the PANS Collaborative Consortium (JCAP-2015) (2014)
Abstract
PANDAS and Comorbid Kleine–Levin Syndrome
Diana M. Gerardi, Joseph Casadonte, Priyal Patel, Tanya K. Murphy (JCAP-2015) (2014)
First Page
Disordered Eating and Food Restrictions in Children with PANDAS/PANS
Megan D. Toufexis, Rebecca Hommer, Diana M. Gerardi, Paul Grant, Leah Rothschild, Precilla D'Souza, Kyle Williams, James Leckman, Susan E. Swedo, Tanya K. Murphy (JCAP-2015) (2014)
Abstract
Cefdinir for Recent-Onset Pediatric Neuropsychiatric Disorders: A Pilot Randomized Trial
Tanya K. Murphy, E. Carla Parker-Athill, Adam B. Lewin, Eric A. Storch, P. Jane Mutch (JCAP-2015) (2014)
Abstract
Characterization of the Pediatric Acute-Onset Neuropsychiatric Syndrome Phenotype
Tanya K. Murphy, Priyal D. Patel, Joseph F. McGuire, Allison Kennel, P. Jane Mutch, E. Carla Parker-Athill, Camille E. Hanks, Adam B. Lewin, Eric A. Storch, Megan D. Toufexis, Gul H. Dadlani, Carina A. Rodriguez (JCAP-2015) (2014)
Abstract
Pediatric inflammatory brain diseases: a diagnostic approach
Van Mater, Heather (Current Opinion in Rheumatology- 2014)
Abstract
Brain Imaging Differences in Tourette and PANDAS
(Medscape Medical News from the Society of Nuclear Medicine and Molecular Imaging (SNMMI) 2014 Annual Meeting – 2014)
Article
Post-infectious autoimmune disorders: Sydenham’s chorea, PANDAS and beyond
Kyle A. Williams, Susan E. Swedo (Elsevier-2014)
Abstract
Evaluation of Basal Ganglia and Thalamic Inflammation in Children With Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcal Infection and Tourette Syndrome-A Positron Emission Tomographic (PET) Study Using 11C-[R]-PK11195
Ajay Kumar, MD, PhD, DNB; Mitchel T. Williams, MD; Harry T. Chugani, MDhttp://jcn.sagepub.com/content/30/6/749 - aff-1 (Journal of Child Neurology-2014)
Abstract
Behavioral and neural effects of intra-striatal infusion of anti-streptococcal antibodies in rats
Dafna Lotan, Itai Benhar, Kathy Alvarez, Adita Mascaro-Blanco, Lior Brimberg, Dan Frenkel, Madeleine W. Cunningham, Daphna Joel (Elsevier-2014)
Abstract
The curious case of the “inseparable child”
Praveen Navkhare, Gurvinder Kalra (Indian Journal of Psychiatry-2014)
Full Text
2013
A Link Between Perianal Strep and Pediatric Autoimmune Neuropsychiatric Disorder Associated With Streptococcal Infection (PANDAS)
Megan Toufexis, D.O.; Caroline DeOleo, M.D.; Josephine Elia, M.D.; Tanya K. Murphy, M.D. (Journal of Neuropsychiatry & Clinical Neurosciences-2013)
Full PDF
Periodic Fever and Hyperimmunoglobulin D Syndrome in a Boy with Pediatric Autoimmune Neuropsychiatric Disorders Associated with Group A β-Hemolytic Streptococcus
Perihan Cam Ray, Didem Arslan Tas, Gonca Gul Celik, Ayşegul Yolga Tahiroglu, Ayşe Avci, and Eren Erken (Journal of Child and Adolescent Psychopharmacology- 2013)
First Page
From Research Subgroup to Clinical Syndrome: Modifying the PANDAS Criteria to Describe PANS (Pediatric Acute-onset Neuropsychiatric Syndrome)
Susan E. Swedo, James F. Leckman, Noel R. Rose (Pediatrics and Therapeutics-2013)
Full PDF
A Case Report of Obsessive-Compulsive Disorder Following Acute Disseminated Encephalomyelitis
Katherine E. Muir, Katherine S. McKenney, Mary B. Connolly, S. Evelyn Stewart (AAP Gateway-2013)
Read More
Full PDF
Dopamine Receptor Autoantibodies Correlate with Symptoms in Sydenham's Chorea
Hilla Ben-Pazi, Julie A. Stoner, and Madeleine W. Cunningham (PLoS One-2013)
Full Study
2012-2011
Lyme disease and pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS): an overview
Hanna Rhee, Daniel J Cameron (Int’l Journal of General Medicine-2012)
Full Paper
Behavioral, pharmacological, and immunological abnormalities after streptococcal exposure: a novel rat model of Sydenham chorea and related neuropsychiatric disorders.
Brimberg L, Benhar I, Mascaro-Blanco A, Alvarez K, Lotan D, Winter C, Klein J, Moses AE, Somnier FE, Leckman JF, Swedo SE, Cunningham MW, Joel D (Neuropsychopharmacology-2012 Aug)
Abstract
A case of PANDAS with Kleine–Levin type periodic hypersomnia
Abhijit Das, Ashalatha Radhakrishnan (Sleep Medicine-2012)
Abstract
Neurocognitive Functioning in Youth With Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcus
Adam B. Lewin, Ph.D., A.B.P.P., Eric A. Storch, Ph.D., P. Jane Mutch, Ph.D., Tanya K. Murphy, M.D. (J Neuropsychiatry Clin Neurosci - 2011)
Full PDF
Clinical Factors Associated with PANDAS
Tanya K. Murphy, MD, Eric A. Storch, PhD, Adam B. Lewin, PhD., Paula J. Edge, BS., and Wayne K. Goodman, MD (Journal of Pediatrics – 2011)
Abstract
Neurocognitive functioning in youth with pediatric autoimmune neuropsychiatric disorders associated with streptococcus
Lewin AB, Storch EA, Mutch PJ, Murphy TK (J Neuropsychiatry Clin Neurosci - 2011)
Abstract
Pediatric autoimmune neuropsychiatric disorders associated with Streptococcus in identical siblings.
Lewin AB, Storch EA, Murphy TK (J Neuropsychiatry Clin Neurosci - 2011)
Abstract
Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS): an indication for tonsillectomy
Alexander AA, Patel NJ, Southammakosane CA, Mortensen MM (Int J Pediatr Otorhinolaryngol. – 2011)
Abstract
Oral inflammatory process and general health. Part 2: How does the periapical inflammatory process compromise general health?
Somma F, Castagnola R, Bollino D, Marigo L (Eur Rev Med Pharmacol Sci. – 2011)
Abstract
Maternal History of Autoimmune Disease in Children Presenting with Tics and/or Obsessive-Compulsive Disorder
T.K. Murphy, E.A. Storch, A. Turner, J.M. Reid, J. Tan, A.B. Lewin (J Neuroimmunol – 2011)
Full Article
2009-1999
The relationship between group A beta hemolytic streptococcal infection and psychiatric symptoms: a pilot study
Cengel-Kültür SE, Cöp E, Kara A, Cengiz AB, Uludağ AK, Unal F (Turk J Pediatr- 2009)
Abstract
Cross-cutting issues and future directions for the OCD spectrum.
Hollander E, Kim S, Braun A, Simeon D, Zohar J (Psychiatry Res. – 2009)
Abstract
Executive and Attention Functioning Among Children in the Pandas Subgroup
Matthew E. Hirschtritt, Christopher J. Hammond, David Luckenbaugh, Jason Buhle, Audrey E. Thurm, B. J. Casey, and Susan E. Swedo (Child Neuropsychol. – 2009)
Full Article
Challenges in the identification and treatment of PANDAS: a case series.
Mabrouk AA, Eapen V (J Trop Pediatr - 2009)
Abstract
Neuropsychiatric Disorders Associated with Streptococcal Infection: A Case-Control Study among Privately Insured Children
Douglas L. Leslie, Ph.D., Laura Kozma, B.A., Andrés Martin, M.D., M.P.H., Angeli Landeros, M.D., Liliya Katsovich, M.B.A., Robert A. King, M.D., James F. Leckman, M.D. (J Am Acad Child Adolesc Psychiatry – 2009)
Full Article
Mycoplasma pneumoniae infection and obsessive-compulsive disease: a case report
Ercan TE, Ercan G, Severge B, Arpaozu M, Karasu G (J Child Neurol.- 2008 Mar)
Abstract
Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcus: Comparison of Diagnosis and Treatment in the Community and at a Specialty Clinic
Vilma Gabbay, MD, Barbara J. Coffey, MD, MS,a James S. Babb, PhD, Laura Meyer, MD, Carly Wachtel, MD, Seeba Anam, MD, Beth Rabinovitz, BA (Pediatrics - 2008)
Full Article
Certain Eating Disorders May Be a Neuropsychiatric Manifestation of PANDAS: Case Report
Cynthia V. Calkin, MD, Carlo G. Carandang, MD ABPN (J Can Acad Child Adolesc Psychiatry – 2007)
Full Article
Relationship of movements and behaviors to Group A Streptococcus infections in elementary school children
Murphy TK, Snider LA, Mutch PJ, Harden E, Zaytoun A, Edge PJ, Storch EA, Yang MC, Mann G, Goodman WK, Swedo SE (Biol Psychiatry – 2007)
Abstract
Selective Serotonin Reuptake Inhibitor-Induced Behavioral Activation in the PANDAS Subtype
Tanya K. Murphy, MD, Eric A. Storch, PhD, and Melissa S. Strawser, BA (Primary Psychiatry-2006)
Full PDF
Strep and Urinary Frequency: Is There a Connection?
Christina Kim, MD, Steven G. Docimo, MD, Kathleen McKay, PhD (NE Section of the American Urological Association -2006)
Article
Tourette's syndrome: a cross sectional study to examine the PANDAS hypothesis
A Church, R Dale, A Lees, G Giovannoni, and M Robertson (J Neurol Neurosurg Psychiatry -2003)
Full PDF
The PANDAS subgroup: recognition and treatment
Swedo SE, Garvey M, Snider L, Hamilton C, Leonard HL (CNS Spectr – 2001)
Abstract
PANDAS Variant and Body Dysmorphic Disorder
Sanjay Mathew (American Journal of Psychiatry-2001)
Letter to Editor
Therapeutic plasma exchange and intravenous immunoglobulin for obsessive-compulsive disorder and tic disorders in childhood
Perlmutter SJ, Leitman SF, Garvey MA, Hamburger S, Feldman E, Leonard HL, Swedo SE (Lancet -1999)
Abstract
Therapeutic plasma exchange and intravenous immunoglobulin for obsessive-compulsive disorder and tic disorders in childhood.
Perlmutter SJ, Leitman SF, Garvey MA, Hamburger S, Feldman E, Leonard HL, Swedo SE (Lancet – 1999)
Abstract
Upcoming research:
Books
Candelaria Greene
Doran Rice
Beth Maloney
Joshua;s Missing Piece
In a pickle over pandas
Videos
https://youtu.be/yIQEMcHoXlM
General Resources
Little known disorder underscores education needs
By Patricia Rice Doran (Baltimore Sun-2014)
Read More
Families’ Experiences with PANDAS and Related Disorders
by Patricia Rice Doran of Towson University presented at the Council for Exceptional Children 2015 annual convention.
Read More
Considerations Regarding Academic Accommodations/Compensatory Strategies, and Services for Students with PANDAS/PANS
Jamie Candelaria Greene PhD, BCET
Read More at PandasNetwork
Pediatric Autoimmune Neuropsychiatric Disorders: A New Frontier for Occupational Therapy Intervention
Trudy Posner & Janice Tona
Read More
PANDAS School Daze Series: Back to School Lessons
Read More at PANDAS Sucks Blog
Letters to School
Letter Requesting Notification of Strep Exposure from Classmates
Read More at PandasNetwork
Letter to School while in PANDAS Exacerbation
Read More at PandasNetwork
Letter to School while in Remission
Read More at PandasNetwork